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Androgen regulation of epithelial–mesenchymal transition in prostate tumorigenesis

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Pages 469-482 | Published online: 10 Jan 2014

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Muhammad Shahid, Min Young Lee, Honit Piplani, Allen M. Andres, Bo Zhou, Austin Yeon, Minjung Kim, Hyung L. Kim & Jayoung Kim. (2018) Centromere protein F (CENPF), a microtubule binding protein, modulates cancer metabolism by regulating pyruvate kinase M2 phosphorylation signaling. Cell Cycle 17:24, pages 2802-2818.
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Lauren N Hendrix, David A Hamilton$suffix/text()$suffix/text() & Natasha Kyprianou. (2013) Emerging therapeutics targeting castration-resistant prostate cancer: the AR-mageddon of tumor epithelial–mesenchymal transition. Expert Review of Endocrinology & Metabolism 8:4, pages 403-416.
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Gail P Risbridger. (2011) Contemporary approaches to prostate cancer research. Expert Review of Endocrinology & Metabolism 6:3, pages 299-300.
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Articles from other publishers (33)

Savitha Rajarajan, V.P Snijesh, C.E Anupama, Madhumathy G Nair, Apoorva D Mavatkar, Chandrakala M Naidu, Sharada Patil, Vidya P Nimbalkar, Annie Alexander, Maalavika Pillai, Mohit Kumar Jolly, Radhakrishnan Sabarinathan, Rakesh S Ramesh, Srinath BS & Jyothi S Prabhu. (2023) An androgen receptor regulated gene score is associated with epithelial to mesenchymal transition features in triple negative breast cancers. Translational Oncology 37, pages 101761.
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Hüseyin ABDİK, Arya Lal ERKILINÇOĞLU & Fikrettin ŞAHİN. (2022) DIFFERENTIATED PRE-ADIPOCYTES ACT AS A DRIVING FORCE FOR PROSTATE CANCER PROLIFERATION, MIGRATION AND EPITHELIAL-MESENCHYMAL TRANSITION. Trakya University Journal of Natural Sciences 23:1, pages 29-36.
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Sofia Papanikolaou, Aikaterini Vourda, Spyros Syggelos & Kostis Gyftopoulos. (2021) Cell Plasticity and Prostate Cancer: The Role of Epithelial–Mesenchymal Transition in Tumor Progression, Invasion, Metastasis and Cancer Therapy Resistance. Cancers 13:11, pages 2795.
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Yuki Otani, Osamu Ichii, Md. Abdul Masum, Takashi Namba, Teppei Nakamura & Yasuhiro Kon. (2021) Castrated autoimmune glomerulonephritis mouse model shows attenuated glomerular sclerosis with altered parietal epithelial cell phenotype. Experimental Biology and Medicine 246:11, pages 1318-1329.
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Yongyan Deng, Hongjin Li & Yujiao Tang. (2021) The Effect of Suppression Taurine on Relocation and Epithelial-Mesenchymal Transition in Mankind Lung Cancer Cells. Journal of Healthcare Engineering 2021, pages 1-11.
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Vipendra Kumar Singh, Rajesh Pal, Priyansh Srivastava, Gauri Misra, Yogeshwer Shukla & Pradeep Kumar Sharma. (2021) Exposure of androgen mimicking environmental chemicals enhances proliferation of prostate cancer (LNCaP) cells by inducing AR expression and epigenetic modifications. Environmental Pollution 272, pages 116397.
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Namrata Khurana, Partha K. Chandra, Hogyoung Kim, Asim B. Abdel-Mageed, Debasis Mondal & Suresh C. Sikka. (2020) Bardoxolone-Methyl (CDDO-Me) Suppresses Androgen Receptor and Its Splice-Variant AR-V7 and Enhances Efficacy of Enzalutamide in Prostate Cancer Cells. Antioxidants 9:1, pages 68.
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Jennifer Munkley, Ling Li, S R Gokul Krishnan, Gerald Hysenaj, Emma Scott, Caroline Dalgliesh, Htoo Zarni Oo, Teresa Mendes Maia, Kathleen Cheung, Ingrid Ehrmann, Karen E Livermore, Hanna Zielinska, Oliver Thompson, Bridget Knight, Paul McCullagh, John McGrath, Malcolm Crundwell, Lorna W Harries, Mads Daugaard, Simon Cockell, Nuno L Barbosa-Morais, Sebastian Oltean & David J Elliott. (2019) Androgen-regulated transcription of ESRP2 drives alternative splicing patterns in prostate cancer. eLife 8.
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Moon‐Sung Lee, Jaeseob Lee, Young‐Myeong Kim & Hansoo Lee. (2019) The metastasis suppressor CD82/KAI1 represses the TGF‐β 1 and Wnt signalings inducing epithelial‐to‐mesenchymal transition linked to invasiveness of prostate cancer cells . The Prostate 79:12, pages 1394-1405.
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Haley Dicken, Patrick J. Hensley & Natasha Kyprianou. (2019) Prostate tumor neuroendocrine differentiation via EMT: The road less traveled. Asian Journal of Urology 6:1, pages 82-90.
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Channing Paller, Hong Pu, Diane E. Begemann, Cameron A. Wade, Patrick J. Hensley & Natasha Kyprianou. (2018) TGF‐β receptor I inhibitor enhances response to enzalutamide in a pre‐clinical model of advanced prostate cancer. The Prostate 79:1, pages 31-43.
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Vidya P. Ramamurthy, Senthilmurugan Ramalingam, Lalji K. Gediya & Vincent C. O. Njar. (2018) The retinamide VNLG ‐152 inhibits f‐AR / AR ‐V7 and MNK – eIF 4E signaling pathways to suppress EMT and castration‐resistant prostate cancer xenograft growth . The FEBS Journal 285:6, pages 1051-1063.
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Hong Pu, Diane E. Begemann & Natasha Kyprianou. (2017) Aberrant TGF-β Signaling Drives Castration-Resistant Prostate Cancer in a Male Mouse Model of Prostate Tumorigenesis. Endocrinology 158:6, pages 1612-1622.
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Lu Miao, Lin Yang, Rui Li, Daniel N. Rodrigues, Mateus Crespo, Jer-Tsong Hsieh, Wayne D. Tilley, Johann de Bono, Luke A. Selth & Ganesh V. Raj. (2017) Disrupting Androgen Receptor Signaling Induces Snail-Mediated Epithelial–Mesenchymal Plasticity in Prostate Cancer. Cancer Research 77:11, pages 3101-3112.
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Mary Nakazawa & Natasha Kyprianou. (2017) Epithelial-mesenchymal-transition regulators in prostate cancer: Androgens and beyond. The Journal of Steroid Biochemistry and Molecular Biology 166, pages 84-90.
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Dibash K. Das, Michelle Naidoo, Adeodat Ilboudo, Jong Y. Park, Thahmina Ali, Konstantinos Krampis, Brian D. Robinson, Joseph R. Osborne & Olorunseun O. Ogunwobi. (2016) miR-1207-3p regulates the androgen receptor in prostate cancer via FNDC1/fibronectin. Experimental Cell Research 348:2, pages 190-200.
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Patrick J. Hensley, Daniel Zetter, Craig M. Horbinski, Stephen E. Strup & Natasha Kyprianou. (2016) Association of epithelial-mesenchymal transition and nuclear cofilin with advanced urothelial cancer. Human Pathology 57, pages 68-77.
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Tanvir Alam, Mahmut Uludag, Magbubah Essack, Adil Salhi, Haitham Ashoor, John B. Hanks, Craig Kapfer, Katsuhiko Mineta, Takashi Gojobori & Vladimir B. Bajic. (2016) FARNA: knowledgebase of inferred functions of non-coding RNA transcripts. Nucleic Acids Research, pages gkw973.
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Ana Emília Goulart Lemos, Luciana Bueno Ferreira, Nadia Maria Batoreu, Paula Priscilla de Freitas, Martin Hernan Bonamino & Etel Rodrigues Pereira Gimba. (2016) PCA3 long noncoding RNA modulates the expression of key cancer-related genes in LNCaP prostate cancer cells. Tumor Biology 37:8, pages 11339-11348.
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Wei-Yu Chen, Kuo-Tai Hua, Wei-Jiunn Lee, Yung-Wei Lin, Yen-Nien Liu, Chi-Long Chen, Yu-Ching Wen & Ming-Hsien Chien. (2016) Akt Activation Correlates with Snail Expression and Potentially Determines the Recurrence of Prostate Cancer in Patients at Stage T2 after a Radical Prostatectomy. International Journal of Molecular Sciences 17:8, pages 1194.
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Sujitra Detchokul, Aparna Elangovan, Edmund J. Crampin, Melissa J. Davis & Albert G. Frauman. (2015) Network analysis of an in vitro model of androgen-resistance in prostate cancer. BMC Cancer 15:1.
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Julia K. Seibert, Luca Quagliata, Cristina Quintavalle, Thomas G. Hammond, Luigi Terracciano & Alex Odermatt. (2015) A role for the dehydrogenase DHRS7 (SDR34C1) in prostate cancer. Cancer Medicine 4:11, pages 1717-1729.
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Jennifer L Bishop, Alastair Davies, Kirsi Ketola & Amina Zoubeidi. (2015) Regulation of tumor cell plasticity by the androgen receptor in prostate cancer. Endocrine-Related Cancer 22:3, pages R165-R182.
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Sarah K. Martin, Carmen A. Banuelos, Marianne D. Sadar & Natasha Kyprianou. (2015) N-terminal targeting of androgen receptor variant enhances response of castration resistant prostate cancer to taxane chemotherapy. Molecular Oncology 9:3, pages 628-639.
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Hao Liu, Jiang Yin, Hongsheng Wang, Guanmin Jiang, Min Deng, Ge Zhang, Xianzhang Bu, Shaohui Cai, Jun Du & Zhimin He. (2015) FOXO3a modulates WNT/β-catenin signaling and suppresses epithelial-to-mesenchymal transition in prostate cancer cells. Cellular Signalling 27:3, pages 510-518.
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Sarah K. Martin & Natasha Kyprianou. 2015. 123 158 .
Gail S. Prins & Mark Lindgren. 2015. Knobil and Neill's Physiology of Reproduction. Knobil and Neill's Physiology of Reproduction 773 804 .
Zong-cai Liu, Hong-sheng Wang, Ge Zhang, Hao Liu, Xiao-hui Chen, Fan Zhang, Dan-yang Chen, Shao-hui Cai & Jun Du. (2014) AKT/GSK-3β regulates stability and transcription of snail which is crucial for bFGF-induced epithelial–mesenchymal transition of prostate cancer cells. Biochimica et Biophysica Acta (BBA) - General Subjects 1840:10, pages 3096-3105.
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Lorenz C Hofbauer, Tilman D Rachner, Robert E Coleman & Franz Jakob. (2014) Endocrine aspects of bone metastases. The Lancet Diabetes & Endocrinology 2:6, pages 500-512.
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Mercedes Marín-Aguilera, Jordi Codony-Servat, Òscar Reig, Juan José Lozano, Pedro Luis Fernández, María Verónica Pereira, Natalia Jiménez, Michael Donovan, Pere Puig, Lourdes Mengual, Raquel Bermudo, Albert Font, Enrique Gallardo, María José Ribal, Antonio Alcaraz, Pere Gascón & Begoña Mellado. (2014) Epithelial-to-Mesenchymal Transition Mediates Docetaxel Resistance and High Risk of Relapse in Prostate Cancer. Molecular Cancer Therapeutics 13:5, pages 1270-1284.
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Patrick J. Hensley, Andreas Desiniotis, Chi Wang, Arnold Stromberg, Ching-Shih Chen & Natasha Kyprianou. (2014) Novel Pharmacologic Targeting of Tight Junctions and Focal Adhesions in Prostate Cancer Cells. PLoS ONE 9:1, pages e86238.
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Emily A. Matuszak & Natasha Kyprianou. (2013) Expression patterns of epithelial-mesenchymal transition markers in localized prostate cancer: significance in clinicopathological outcomes following radical prostatectomy. BJU International 111:1, pages 6-7.
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