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Expert Review of Endocrinology & Metabolism Volume 6, 2011 - Issue 3
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Review

Obesity, aromatase and breast cancer

Evan R Simpson Prince Henry’s Institute of Medical Research, and the Departments of Biochemistry and Physiology, Monash University, Clayton, Victoria 3168, Australia;[email protected]
&
Kristy A Brown Prince Henry’s Institute of Medical Research, and the Departments of Biochemistry and Physiology, Monash University, Clayton, Victoria 3168, Australia; Prince Henry’s Institute of Medical Research, and the Departments of Biochemistry and Physiology, Monash University, Clayton, Victoria 3168, Australia
Pages 383-395 | Published online: 10 Jan 2014

Citations (13)

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Read on this site (2)

Zeina Nahleh. (2011) Breast cancer, obesity and hormonal imbalance: a worrisome trend. Expert Review of Anticancer Therapy 11:6, pages 817-819.
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Lev M Berstein. (2011) Endocrinology of breast cancer: results, tasks and hopes. Expert Review of Endocrinology & Metabolism 6:3, pages 293-297.
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Articles from other publishers (11)

Saritha Vara, Manoj Kumar Karnena & Bhavya Kavitha Dwarapureddi. 2021. A Theranostic and Precision Medicine Approach for Female-Specific Cancers. A Theranostic and Precision Medicine Approach for Female-Specific Cancers 71 90 .
Derek F. Amanatullah, John S. Tamaresis, Pauline Chu, Michael H. Bachmann, Nhat M. Hoang, Deborah Collyar, Aaron T. Mayer, Robert B. West, William J. Maloney, Christopher H. Contag & Bonnie L. King. (2017) Local estrogen axis in the human bone microenvironment regulates estrogen receptor-positive breast cancer cells. Breast Cancer Research 19:1.
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Xuyi Wang, Evan R. Simpson & Kristy A. Brown. (2015) Aromatase overexpression in dysfunctional adipose tissue links obesity to postmenopausal breast cancer. The Journal of Steroid Biochemistry and Molecular Biology 153, pages 35-44.
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Xuyi Wang, Maria M. Docanto, Hironobu Sasano, Camden Lo, Evan R. Simpson & Kristy A. Brown. (2015) Prostaglandin E2 Inhibits p53 in Human Breast Adipose Stromal Cells: A Novel Mechanism for the Regulation of Aromatase in Obesity and Breast Cancer. Cancer Research 75:4, pages 645-655.
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Maria M. Docanto, Fangyuan Yang, Brid Callaghan, CheukMan C. Au, Rahini Ragavan, Xuyi Wang, John B. Furness, Zane B. Andrews & Kristy A. Brown. (2014) Ghrelin and des-acyl ghrelin inhibit aromatase expression and activity in human adipose stromal cells: suppression of cAMP as a possible mechanism. Breast Cancer Research and Treatment 147:1, pages 193-201.
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Nirukshi U. Samarajeewa, Maria M. Docanto, Evan R. Simpson & Kristy A. Brown. (2013) CREB-Regulated Transcription Co-Activator Family Stimulates Promoter II-Driven Aromatase Expression in Preadipocytes. Hormones and Cancer 4:4, pages 233-241.
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Nilesh W. Gaikwad. (2013) Metabolomic Profiling Unravels DNA Adducts in Human Breast That Are Formed from Peroxidase Mediated Activation of Estrogens to Quinone Methides. PLoS ONE 8:6, pages e65826.
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Irina A. Pikuleva & Michael R. Waterman. (2013) Cytochromes P450: Roles in Diseases. Journal of Biological Chemistry 288:24, pages 17091-17098.
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Nilesh W. Gaikwad. (2013) Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry Method for Profiling of Steroid Metabolome in Human Tissue. Analytical Chemistry 85:10, pages 4951-4960.
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Nirukshi U Samarajeewa, Fangyuan Yang, Maria M Docanto, Minako Sakurai, Keely M McNamara, Hironobu Sasano, Stephen B Fox, Evan R Simpson & Kristy A Brown. (2013) HIF-1α stimulates aromatase expression driven by prostaglandin E2 in breast adipose stroma. Breast Cancer Research 15:2.
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Kristy A. Brown, Nirukshi U. Samarajeewa & Evan R. Simpson. (2013) Endocrine-related cancers and the role of AMPK. Molecular and Cellular Endocrinology 366:2, pages 170-179.
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