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Transmembrane mucins as novel therapeutic targets

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Pages 835-848 | Published online: 10 Jan 2014

Keep up to date with the latest research on this topic with citation updates for this article.

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Carlos Urey, Bodil Andersson, Daniel Ansari, Agata Sasor, Katarzyna Said-Hilmersson, Johan Nilsson & Roland Andersson. (2017) Low MUC4 expression is associated with survival benefit in patients with resectable pancreatic cancer receiving adjuvant gemcitabine. Scandinavian Journal of Gastroenterology 52:5, pages 595-600.
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Articles from other publishers (19)

Ashleigh Hull, William Hsieh, William Tieu, Dylan Bartholomeusz, Yanrui Li & Eva Bezak. (2023) In vitro characterisation of [177Lu]Lu-DOTA-C595 as a novel radioimmunotherapy for MUC1-CE positive pancreatic cancer. EJNMMI Radiopharmacy and Chemistry 8:1.
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Ashleigh Hull, Yanrui Li, Dylan Bartholomeusz, William Hsieh, William Tieu, Tara L. Pukala, Alexander H. Staudacher & Eva Bezak. (2022) Preliminary Development and Testing of C595 Radioimmunoconjugates for Targeting MUC1 Cancer Epitopes in Pancreatic Ductal Adenocarcinoma. Cells 11:19, pages 2983.
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Luana Barbosa Corrêa, Suyene Rocha Pinto, Luciana Magalhães Rebelo Alencar, Sotiris Missailidis, Elaine Cruz Rosas, Maria das Graças Muller de Oliveira Henriques & Ralph Santos-Oliveira. (2022) Nanoparticle conjugated with aptamer anti-MUC1/Y for inflammatory arthritis. Colloids and Surfaces B: Biointerfaces 211, pages 112280.
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Shivanand Pudakalakatti, José S. Enriquez, Caitlin McCowan, Saleh Ramezani, Jennifer S. Davis, Niki M. Zacharias, Dontrey Bourgeois, Pamela E. Constantinou, Daniel A. Harrington, Daniel Carson, Mary C. Farach‐Carson & Pratip K. Bhattacharya. (2021) Hyperpolarized MRI with silicon micro and nanoparticles: Principles and applications . WIREs Nanomedicine and Nanobiotechnology 13:6.
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Elizabeth Pham, Matthias Friedrich, Famke Aeffner, Michael Lutteropp, Natalie F. Mariano, Petra Deegen, Christoph Dahlhoff, Franziska Vogel, Claudia Bluemel, John M. Harrold, Christian Brandl, Natalia Grinberg, Benno Rattel, Angela Coxon & Julie M. Bailis. (2021) Preclinical Assessment of a MUC12-Targeted BiTE (Bispecific T-cell Engager) Molecule. Molecular Cancer Therapeutics 20:10, pages 1977-1987.
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Rafael Martinez-Carrasco, Pablo Argüeso & M. Elizabeth Fini. (2021) Membrane-associated mucins of the human ocular surface in health and disease. The Ocular Surface 21, pages 313-330.
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Ashleigh Hull, Yanrui Li, Dylan Bartholomeusz, William Hsieh, Samantha Escarbe, Andrew Ruszkiewicz & Eva Bezak. (2020) The Expression Profile and Textural Characteristics of C595-Reactive MUC1 in Pancreatic Ductal Adenocarcinoma for Targeted Radionuclide Therapy. Cancers 13:1, pages 61.
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Bina Kashyap & Arja M. Kullaa. (2020) Regulation of mucin 1 expression and its relationship with oral diseases. Archives of Oral Biology 117, pages 104791.
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B.W. Huisman, J. Burggraaf, A.L. Vahrmeijer, J.W. Schoones, R.A. Rissmann, C.F.M. Sier & M.I.E. van Poelgeest. (2020) Potential targets for tumor-specific imaging of vulvar squamous cell carcinoma: A systematic review of candidate biomarkers. Gynecologic Oncology 156:3, pages 734-743.
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M. Elizabeth Fini, Shinwu Jeong, Haiyan Gong, Rafael Martinez-Carrasco, Nora M.V. Laver, Minako Hijikata, Naoto Keicho & Pablo Argüeso. (2020) Membrane-associated mucins of the ocular surface: New genes, new protein functions and new biological roles in human and mouse. Progress in Retinal and Eye Research 75, pages 100777.
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Silvia Catuogno, Carla Esposito, Paola Ungaro & Vittorio de Franciscis. (2018) Nucleic Acid Aptamers Targeting Epigenetic Regulators: An Innovative Therapeutic Option. Pharmaceuticals 11:3, pages 79.
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Pamela A. Trail, Gene M. Dubowchik & Timothy B. Lowinger. (2018) Antibody drug conjugates for treatment of breast cancer: Novel targets and diverse approaches in ADC design. Pharmacology & Therapeutics 181, pages 126-142.
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Pengpeng Xia, Agnes Hakyung Choi, Zengping Deng, Yuqian Yang, Jing Zhao, Yiting Wang, Philip R. Hardwidge & Guoqiang Zhu. (2016) Cell membrane-anchored MUC4 promotes tumorigenicity in epithelial carcinomas. Oncotarget 8:8, pages 14147-14157.
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Micaela Morgado, Margie N. Sutton, Mary Simmons, Curtis R. Warren, Zhen Lu, Pamela E. Constantinou, Jinsong Liu, Lewis LW. Francis, R. Steven Conlan, Robert C. BastJr.Jr. & Daniel D. Carson. (2016) Tumor necrosis factor-α and interferon-γ stimulate MUC16 (CA125) expression in breast, endometrial and ovarian cancers through NFκB. Oncotarget 7:12, pages 14871-14884.
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Agnieszka Gornowicz, Anna Bielawska, Robert Czarnomysy, Halina Gabryel-Porowska, Anna Muszyńska & Krzysztof Bielawski. (2015) The combined treatment with novel platinum(II) complex and anti-MUC1 increases apoptotic response in MDA-MB-231 breast cancer cells. Molecular and Cellular Biochemistry 408:1-2, pages 103-113.
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Tania Patino, Ujjwal Mahajan, Raghavendra Palankar, Nikolay Medvedev, Jakob Walowski, Markus Münzenberg, Julia Mayerle & Mihaela Delcea. (2015) Multifunctional gold nanorods for selective plasmonic photothermal therapy in pancreatic cancer cells using ultra-short pulse near-infrared laser irradiation. Nanoscale 7:12, pages 5328-5337.
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Isabella Tavernaro, Sebastian Hartmann, Laura Sommer, Heike Hausmann, Christian Rohner, Martin Ruehl, Anja Hoffmann-Roeder & Sabine Schlecht. (2015) Synthesis of tumor-associated MUC1-glycopeptides and their multivalent presentation by functionalized gold colloids. Organic & Biomolecular Chemistry 13:1, pages 81-97.
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Justin P Dassie & Paloma H Giangrande. (2013) Current progress on aptamer-targeted oligonucleotide therapeutics. Therapeutic Delivery 4:12, pages 1527-1546.
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Furong Dai, Yi Zhang, Xin Zhu, Nianchun Shan & Yuxiang Chen. (2012) Anticancer role of MUC1 aptamer–miR-29b chimera in epithelial ovarian carcinoma cells through regulation of PTEN methylation. Targeted Oncology 7:4, pages 217-225.
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