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Review

Role of nucleophosmin in acute myeloid leukemia

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Pages 1283-1294 | Published online: 10 Jan 2014

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Zhiyong Wang, Jonathan M. Gall, Ramon Bonegio, Andrea Havasi, Katarina Illanes, John H. Schwartz & Steven C. Borkan. (2013) Nucleophosmin, a Critical Bax Cofactor in Ischemia-Induced Cell Death. Molecular and Cellular Biology 33:10, pages 1916-1924.
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Georg Hopfinger, Robert Griessl, Eveline Sifft, Ninon Taylor, Lukas Kenner, Richard Greil & Olaf Merkel. (2012) Novel treatment avenues for peripheral T-cell lymphomas. Expert Opinion on Drug Discovery 7:12, pages 1149-1163.
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Christopher D Watt & Adam Bagg. (2010) Molecular diagnosis of acute myeloid leukemia. Expert Review of Molecular Diagnostics 10:8, pages 993-1012.
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Articles from other publishers (25)

Aleš Holoubek, Dita Strachotová, Petra Otevřelová, Pavla Röselová, Petr Heřman & Barbora Brodská. (2021) AML-Related NPM Mutations Drive p53 Delocalization into the Cytoplasm with Possible Impact on p53-Dependent Stress Response. Cancers 13:13, pages 3266.
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Markéta Šašinková, Petr Heřman, Aleš Holoubek, Dita Strachotová, Petra Otevřelová, Dana Grebeňová, Kateřina Kuželová & Barbora Brodská. (2021) NSC348884 cytotoxicity is not mediated by inhibition of nucleophosmin oligomerization. Scientific Reports 11:1.
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Anna Gueiderikh, Frédérique Maczkowiak-ChartoisGuillaume RouvetSylvie Souquère-Besse, Sébastien ApcherJean-Jacques Diaz & Filippo Rosselli. (2021) Fanconi anemia A protein participates in nucleolar homeostasis maintenance and ribosome biogenesis. Science Advances 7:1.
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H. Hoffmann, C. Thiede, I. Glauche, M. Bornhaeuser & I. Roeder. (2020) Differential response to cytotoxic therapy explains treatment dynamics of acute myeloid leukaemia patients: insights from a mathematical modelling approach. Journal of The Royal Society Interface 17:170, pages 20200091.
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Uday Younis Hussein Abdullah, Nordin Simbak, Marwan Saad Azzubaidi, Raudhawati Osman, Hishamshah M. Ibrahim, Haitham Muhammed Jassim, Noraini Mat Yunus, Muhammad Farid Johan, Zilfalil Bin Alwi, Lay Kek Teh, Mohd Nur Fakhruzzaman & Mohd Zaki Salleh. (2020) Hyperleucocytosis grading score and NPM1 gene mutation among patients with acute myeloid leukemia: Malaysian experience. Journal of Hematopathology 13:1, pages 33-40.
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Barbora Brodská, Markéta Šašinková & Kateřina Kuželová. (2019) Nucleophosmin in leukemia: Consequences of anchor loss. The International Journal of Biochemistry & Cell Biology 111, pages 52-62.
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Concetta Di Natale, Sara La Manna, Anna Maria Malfitano, Sarah Di Somma, Daniele Florio, Pasqualina Liana Scognamiglio, Ettore Novellino, Paolo Antonio Netti & Daniela Marasco. (2019) Structural insights into amyloid structures of the C-terminal region of nucleophosmin 1 in type A mutation of acute myeloid leukemia. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 1867:6, pages 637-644.
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Durga Attili, Shannon D. McClintock, Areeba H. Rizvi, Shailja Pandya, Humza Rehman, Daniyal M. Nadeem, Aliah Richter, Dafydd Thomas, Michael K. Dame, Danielle Kim Turgeon, James Varani & Muhammad N. Aslam. (2019) Calcium-induced differentiation in normal human colonoid cultures: Cell-cell / cell-matrix adhesion, barrier formation and tissue integrity. PLOS ONE 14:4, pages e0215122.
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Aleš Holoubek, Petr Herman, Jan Sýkora, Barbora Brodská, Jana Humpolíčková, Markéta Kráčmarová, Dana Gášková, Martin Hof & Kateřina Kuželová. (2018) Monitoring of nucleophosmin oligomerization in live cells. Methods and Applications in Fluorescence 6:3, pages 035016.
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Preethi Kunchala, Sudhakiranmayi Kuravi, Roy Jensen, Joseph McGuirk & Ramesh Balusu. (2018) When the good go bad: Mutant NPM1 in acute myeloid leukemia. Blood Reviews 32:3, pages 167-183.
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Siwei Wang, Chunxiao Sun, Jianhua Li, Erbao Zhang, Zhifei Ma, Weizhang Xu, Hong Li, Mantang Qiu, Youtao Xu, Wenjia Xia, Lin Xu & Rong Yin. (2017) Roles of RNA methylation by means of N6-methyladenosine (m6A) in human cancers. Cancer Letters 408, pages 112-120.
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C M Cabrera, E Fernández-Grande & J M Urra. (2016) Serological profile and clinical features of nucleolar antinuclear pattern in patients with systemic lupus erythematosus from southwestern Spain. Lupus 25:9, pages 980-987.
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Adele Di Matteo, Mimma Franceschini, Sara Chiarella, Serena Rocchio, Carlo Travaglini-Allocatelli & Luca Federici. (2016) Molecules that target nucleophosmin for cancer treatment: an update. Oncotarget 7:28, pages 44821-44840.
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Jo Ishizawa, Kensuke Kojima, Numsen HailJr.Jr., Yoko Tabe & Michael Andreeff. (2015) Expression, function, and targeting of the nuclear exporter chromosome region maintenance 1 (CRM1) protein. Pharmacology & Therapeutics 153, pages 25-35.
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Mei Liu, Armando Ramirez, Jitian Li, Liping Dai, Renato Aguilera & Jian-Ying Zhang. (2015) Humoral autoimmune response to nucleophosmin in the immunodiagnosis of hepatocellular carcinoma. Oncology Reports.
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Ramesh Balusu, Warren Fiskus & Kapil N. Bhalla. 2015. Targeted Therapy of Acute Myeloid Leukemia. Targeted Therapy of Acute Myeloid Leukemia 251 273 .
William T. Senapedis, Erkan Baloglu & Yosef Landesman. (2014) Clinical translation of nuclear export inhibitors in cancer. Seminars in Cancer Biology 27, pages 74-86.
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Minhui Lin, Jianda Hu, Tingbo Liu, Jing Li, Buyuan Chen & Xinji Chen. (2013) Knockdown of nucleophosmin by RNA interference reverses multidrug resistance in resistant leukemic HL-60 cells. Immunobiology 218:9, pages 1147-1154.
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K.M. Hannan, E. Sanij, L.I. Rothblum, R.D. Hannan & R.B. Pearson. (2013) Dysregulation of RNA polymerase I transcription during disease. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1829:3-4, pages 342-360.
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Gerald B. W. Wertheim, Elizabeth Hexner & Adam Bagg. (2012) Molecular-Based Classification of Acute Myeloid Leukemia and Its Role in Directing Rational Therapy. Molecular Diagnosis & Therapy 16:6, pages 357-369.
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Parvathi Ranganathan, Xueyan Yu, Caroline Na, Ramasamy Santhanam, Sharon Shacham, Michael Kauffman, Alison Walker, Rebecca Klisovic, William Blum, Michael Caligiuri, Carlo M. Croce, Guido Marcucci & Ramiro Garzon. (2012) Preclinical activity of a novel CRM1 inhibitor in acute myeloid leukemia. Blood 120:9, pages 1765-1773.
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Fumihiko Sagawa, Hend Ibrahim, Angela L Morrison, Carol J Wilusz & Jeffrey Wilusz. (2011) Nucleophosmin deposition during mRNA 3′ end processing influences poly(A) tail length. The EMBO Journal 30:19, pages 3994-4005.
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Vikram Narayan, Petr Halada, Lenka Hernychová, Yuh Ping Chong, Jitka Žáková, Ted R. Hupp, Borivoj Vojtesek & Kathryn L. Ball. (2011) A Multiprotein Binding Interface in an Intrinsically Disordered Region of the Tumor Suppressor Protein Interferon Regulatory Factor-1. Journal of Biological Chemistry 286:16, pages 14291-14303.
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Hui-Yuan Shao, Zong-Yu Miao, Hui-Chen, Feng-Xian Qin, Xian-Chun Chen, Shi Tan, Hui-Juan Zhang, Li Wang, Yu-Jie Gao, Zai-Lin Yang & Ling Zhang. (2011) Nucleophosmin gene mutations promote NIH3T3 cell migration and invasion through CXCR4 and MMPs. Experimental and Molecular Pathology 90:1, pages 38-44.
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Wei Du, Jie Li, Jared Sipple, Jianjun Chen & Qishen Pang. (2010) Cytoplasmic FANCA-FANCC Complex Interacts and Stabilizes the Cytoplasm-dislocalized Leukemic Nucleophosmin Protein (NPMc). Journal of Biological Chemistry 285:48, pages 37436-37444.
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