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Expert Review of Anticancer Therapy Volume 10, 2010 - Issue 11
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Theme: Skin Cancer - Key Paper Evaluation

Ipilimumab: attenuation of an inhibitory immune checkpoint improves survival in metastatic melanoma

Karl S Peggs Department of Haematology, UCL Cancer Institute, Paul O’Gorman Building, University College London, 72 Huntley Street, London, WC1E 6BT, UK. [email protected]; Department of Haematology, UCL Cancer Institute, Paul O’Gorman Building, University College London, 72 Huntley Street, London, WC1E 6BT, UK. [email protected]
&
Sergio A Quezada Ludwig Center for Cancer Immunotherapy, Howard Hughes Medical Institute, 1275 York Avenue, New York, NY 10021, USA; Department of Immunology, Memorial Sloan–Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA; Ludwig Center for Cancer Immunotherapy, Howard Hughes Medical Institute, 1275 York Avenue, New York, NY 10021, USA; Department of Immunology, Memorial Sloan–Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
Pages 1697-1701 | Published online: 10 Jan 2014

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Guang-Tao Yu, Lin-Lin Bu, Yu-Yue Zhao, Liang Mao, Wei-Wei Deng, Tian-Fu Wu, Wen-Feng Zhang & Zhi-Jun Sun. (2016) CTLA4 blockade reduces immature myeloid cells in head and neck squamous cell carcinoma. OncoImmunology 5:6.
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Karl S Peggs & Sergio A Quezada. (2012) PD-1 blockade: promoting endogenous anti-tumor immunity. Expert Review of Anticancer Therapy 12:10, pages 1279-1282.
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Xiang-Yang Wang, Daming Zuo, Devanand Sarkar & Paul B Fisher. (2011) Blockade of cytotoxic T-lymphocyte antigen-4 as a new therapeutic approach for advanced melanoma. Expert Opinion on Pharmacotherapy 12:17, pages 2695-2706.
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Dong He, Zhen Qin, Zihao Liu, Xiaoshuai Ji, Jiajia Gao, Hua Guo, Fan Yang, Haitao Fan, Yanbang Wei, Zixiao Wang, Qian Liu & Qi Pang. (2022) Comprehensive Analysis of the Prognostic Value and Immune Infiltration of Butyrophilin Subfamily 2/3 (BTN2/3) Members in Pan-Glioma. Frontiers in Oncology 12.
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Inge Kortekaas Krohn, Joeri L. Aerts, Karine Breckpot, Cleo Goyvaerts, Edward Knol, Femke Van Wijk & Jan Gutermuth. (2021) T‐cell subsets in the skin and their role in inflammatory skin disorders. Allergy 77:3, pages 827-842.
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Bei Wang, Dandan Chen & Haiying Hua. (2021) TBC1D3 family is a prognostic biomarker and correlates with immune infiltration in kidney renal clear cell carcinoma. Molecular Therapy - Oncolytics 22, pages 528-538.
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Olamide T. Olaoba, Funmilayo C. Ligali, Zaccheaus O. Alabi, Amos O. Akinyemi & Kehinde S. Ayinde. (2021) Of immune checkpoint maladies and remedies: The throwing of jabs in the oncogenic ring of PDAC. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1875:1, pages 188483.
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Nune Markosyan, Jinyang Li, Yu H. Sun, Lee P. Richman, Jeffrey H. Lin, Fangxue Yan, Liz Quinones, Yogev Sela, Taiji Yamazoe, Naomi Gordon, John W. Tobias, Katelyn T. Byrne, Andrew J. Rech, Garret A. FitzGerald, Ben Z. Stanger & Robert H. Vonderheide. (2019) Tumor cell–intrinsic EPHA2 suppresses antitumor immunity by regulating PTGS2 (COX-2). Journal of Clinical Investigation 129:9, pages 3594-3609.
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Xing-yu Feng, Lin Lu, Ke-feng Wang, Bao-yan Zhu, Xi-zhi Wen, Rui-qing Peng, Ya Ding, Dan-dan Li, Jing-jing Li, Yong Li & Xiao-shi Zhang. (2019) Low expression of CD80 predicts for poor prognosis in patients with gastric adenocarcinoma. Future Oncology 15:5, pages 473-483.
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Tyler J. Alban, Alvaro G. Alvarado, Mia D. Sorensen, Defne Bayik, Josephine Volovetz, Emily Serbinowski, Erin E. Mulkearns-Hubert, Maksim Sinyuk, James S. Hale, Giovana R. Onzi, Mary McGraw, Pengjing Huang, Matthew M. Grabowski, Connor A. Wathen, Manmeet S. Ahluwalia, Tomas Radivoyevitch, Harley I. Kornblum, Bjarne W. Kristensen, Michael A. Vogelbaum & Justin D. Lathia. (2018) Global immune fingerprinting in glioblastoma patient peripheral blood reveals immune-suppression signatures associated with prognosis. JCI Insight 3:21.
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Patrick Ho & Yvonne Y. Chen. 2018. Synthetic Biology. Synthetic Biology 349 372 .
Edith BorcomanAmara NandikollaGeorgina LongSanjay GoelChristophe Le Tourneau. (2018) Patterns of Response and Progression to Immunotherapy. American Society of Clinical Oncology Educational Book:38, pages 169-178.
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David R. Soto-Pantoja, Adam S. Wilson, Kenysha YJ. Clear, Brian Westwood, Pierre L. Triozzi & Katherine L. Cook. (2017) Unfolded protein response signaling impacts macrophage polarity to modulate breast cancer cell clearance and melanoma immune checkpoint therapy responsiveness. Oncotarget 8:46, pages 80545-80559.
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B. Bonavida & S. Chouaib. (2017) Resistance to anticancer immunity in cancer patients: potential strategies to reverse resistance. Annals of Oncology 28:3, pages 457-467.
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Omar Abdel-Rahman. (2016) Combination or single-agent ipilimumab as immunotherapy of advanced melanoma: a critical review. Melanoma Management 3:3, pages 231-243.
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Jayoung Kim. (2016) Immune checkpoint blockade therapy for bladder cancer treatment. Investigative and Clinical Urology 57:Suppl 1, pages S98.
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Rafael A. Ponce. 2014. Molecular Immunotoxicology. Molecular Immunotoxicology 159 188 .
D. Nikitovic, M. Mytilinaiou, Ai. Berdiaki, N.K. Karamanos & G.N. Tzanakakis. (2014) Heparan sulfate proteoglycans and heparin regulate melanoma cell functions. Biochimica et Biophysica Acta (BBA) - General Subjects 1840:8, pages 2471-2481.
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Isabelle Le Mercier, Wenna Chen, Janet L. Lines, Maria Day, Jiannan Li, Petra Sergent, Randolph J. Noelle & Li Wang. (2014) VISTA Regulates the Development of Protective Antitumor Immunity. Cancer Research 74:7, pages 1933-1944.
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Therese Liechtenstein, Noemi Perez-Janices, Christopher Bricogne, Alessio Lanna, Inès Dufait, Cleo Goyvaerts, Roberta Laranga, Antonella Padella, Frederick Arce, Mehdi Baratchian, Natalia Ramirez, Natalia Lopez, Grazyna Kochan, Idoia Blanco-Luquin, David Guerrero-Setas, Karine Breckpot & David Escors. (2013) Immune modulation by genetic modification of dendritic cells with lentiviral vectors. Virus Research 176:1-2, pages 1-15.
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Ahmad Tarhini. (2013) Immune-Mediated Adverse Events Associated with Ipilimumab CTLA-4 Blockade Therapy: The Underlying Mechanisms and Clinical Management. Scientifica 2013, pages 1-19.
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Pablo A. González, Leandro J. Carreño, Pablo F. Céspedes, Susan M. Bueno, Claudia A. Riedel & Alexis M. Kalergis. (2013) Modulation of Tumor Immunity by Soluble and Membrane-Bound Molecules at the Immunological Synapse. Clinical and Developmental Immunology 2013, pages 1-19.
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J. Stebbing, A. Dalgleish, A. Gifford-Moore, A. Martin, C. Gleeson, G. Wilson, L.R. Brunet, J. Grange & S. Mudan. (2012) An intra-patient placebo-controlled phase I trial to evaluate the safety and tolerability of intradermal IMM-101 in melanoma. Annals of Oncology 23:5, pages 1314-1319.
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Konstantinos LinosAndrzej Slominski, Jeffrey S RossJ Andrew Carlson. (2011) Melanoma update: diagnostic and prognostic factors that can effectively shape and personalize management. Biomarkers in Medicine 5:3, pages 333-360.
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Agustin Lage & Tania Crombet. (2011) Control of Advanced Cancer: The Road to Chronicity. International Journal of Environmental Research and Public Health 8:3, pages 683-697.
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