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Cetuximab in the treatment of squamous cell carcinoma of the head and neck

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Pages 511-524 | Published online: 10 Jan 2014

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Gilmar Hanck-Silva, Lucas Noboru Fatori Trevizan, Raquel Petrilli, Felipe Tita de Lima, Josimar O. Eloy & Marlus Chorilli. (2020) A Critical Review of Properties and Analytical/Bioanalytical Methods for Characterization of Cetuximab. Critical Reviews in Analytical Chemistry 50:2, pages 125-135.
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Pol Specenier & Jan B Vermorken. (2013) Cetuximab: its unique place in head and neck cancer treatment. Biologics: Targets and Therapy 7, pages 77-90.
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Articles from other publishers (29)

Mark Chang, Wolfram Samlowski & Raul Meoz. (2023) Effectiveness and toxicity of cetuximab with concurrent RT in locally advanced cutaneous squamous cell skin cancer: a case series. Oncotarget 14:1, pages 709-718.
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Harshil Shah, Vivek Chavda & Moinuddin M. Soniwala. 2023. Bioinformatics Tools for Pharmaceutical Drug Product Development. Bioinformatics Tools for Pharmaceutical Drug Product Development 95 116 .
Avinash Khadela, Yesha Shah, Priya Mistry, Kunjan Bodiwala & Avinash CB. (2023) Immunomodulatory Therapy in Head and Neck Squamous Cell Carcinoma: Recent Advances and Clinical Prospects. Technology in Cancer Research & Treatment 22, pages 153303382211505.
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Avinash Khadela, Yesha Shah, Priya Mistry, Mustakim Mansuri, Dipen Sureja & Kunjan Bodiwala. (2022) A review of efficacy and safety of cetuximab and bevacizumab-based monoclonal antibodies in head and neck cancer. Medical Oncology 40:1.
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Lev Manevich, Yukari Okita, Yasuhito Okano, Takehito Sugasawa, Kunio Kawanishi, Thanasis Poullikkas, Linda T. L. Dang Cao, Ling Zheng, Masahiro Nakayama, Shin Matsumoto, Keiji Tabuchi & Mitsuyasu Kato. (2022) Glycoprotein NMB promotes tumor formation and malignant progression of laryngeal squamous cell carcinoma. Cancer Science 113:9, pages 3244-3254.
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Corinna Haist, Zoe Poschinski, Arthur Bister, Michèle J. Hoffmann, Camilla M. Grunewald, Alexandra Hamacher, Matthias Kassack, Constanze Wiek, Kathrin Scheckenbach & Helmut Hanenberg. (2022) Engineering a single-chain variable fragment of cetuximab for CAR T-cell therapy against head and neck squamous cell carcinomas. Oral Oncology 129, pages 105867.
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Mehdi Ebrahimi. 2021. Early Detection and Treatment of Head & Neck Cancers. Early Detection and Treatment of Head & Neck Cancers 63 120 .
Eun Kyung Kim, Yoon Ah Cho, Yoon Woo Koh, Hyang Ae Shin, Byoung Chul Cho & Sun Och Yoon. (2020) Prognostic implications of Fibroblast growth factor receptor 1 (FGFR1) gene amplification and protein overexpression in hypopharyngeal and laryngeal squamous cell carcinoma. BMC Cancer 20:1.
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Shilpa Bhatia & Sana D. Karam. 2020. Improving the Therapeutic Ratio in Head and Neck Cancer. Improving the Therapeutic Ratio in Head and Neck Cancer 193 220 .
Francesca del Bufalo & Franco Locatelli. 2020. Neuroblastoma. Neuroblastoma 237 269 .
Fanny Chambon, Sophie Osdoit, Kelly Bagny, Anne Moro, Jacqueline Nguyen & Yves Réguerre. (2018) Dramatic response to nivolumab in xeroderma pigmentosum skin tumor. Pediatric Blood & Cancer 65:2, pages e26837.
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Mei Jiang, Hui Zhang, He Xiao, Zhimin Zhang, Dan Que, Jia Luo, Jian Li, Bijing Mao, Yuanyuan Chen, Meilin Lan, Ge Wang & Hualiang Xiao. (2017) High expression of c‑Met and EGFR is associated with poor survival of patients with glottic laryngeal squamous cell carcinoma. Oncology Letters.
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Shellese A. Cannonier, Cara B. Gonzales, Kim Ely, Scott A. Guelcher & Julie A. Sterling. (2016) Hedgehog and TGFβ signaling converge on Gli2 to control bony invasion and bone destruction in oral squamous cell carcinoma. Oncotarget 7:46, pages 76062-76075.
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XIN LI, LING XU, HEMING LI, LEI ZHAO, YING LUO, ZHITU ZHU, YUNPENG LIU & XIUJUAN QU. (2015) Cetuximab-induced insulin-like growth factor receptor I activation mediates cetuximab resistance in gastric cancer cells. Molecular Medicine Reports 11:6, pages 4547-4554.
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Pol Specenier. 2015. Targeted Therapies for Solid Tumors. Targeted Therapies for Solid Tumors 81 87 .
Sami Salihu, Orhan Güven, Enis Gllareva, Mergime Prekazi & Leminot Salihu. (2014) A clinical study on survival rate of patients with squamous cell carcinoma of the lower lip in Kosovo. Journal of Cranio-Maxillofacial Surgery 42:8, pages 1773-1777.
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Anja Pickhard, Guido Piontek, Christof Seidl, Samuel Kopping, Birgit Blechert, Martin Mißlbeck, Gero Brockhoff, Frank Bruchertseifer, Alfred Morgenstern & Markus Essler. (2014) 213Bi-anti-EGFR radioimmunoconjugates and X-ray irradiation trigger different cell death pathways in squamous cell carcinoma cells. Nuclear Medicine and Biology 41:1, pages 68-76.
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Julia Vent, Bastian Haidle, Inga Wedemeyer, Christian Huebbers, Oliver Siefer, Robert Semrau, Simon F. Preuss & Jens Klussmann. (2013) p16 Expression in carcinoma of unknown primary: Diagnostic indicator and prognostic marker. Head & Neck 35:11, pages 1521-1526.
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C. Matuschek, E. Bölke, C. Belka, U. Ganswindt, M. Henke, P. Stegmaier, M. Bamberg, S. Welz, J. Debus, A. Gioules, A. Voigt, G. Volk, C. Ohmann, T. Wiegel, V. Budach, M. Stuschke, J. Schipper, P.A. Gerber & W. Budach. (2013) Feasibility of 6-month maintenance cetuximab after adjuvant concurrent chemoradiation plus cetuximab in squamous cell carcinoma of the head and neckDurchführbarkeit einer 6-monatigen Cetuximab-Erhaltungstherapie nach adjuvanter gleichzeitiger Chemoradiotherapie plus Cetuximab bei Plattenepithelkarzinomen des Kopf-Hals-Bereichs. Strahlentherapie und Onkologie 189:8, pages 625-631.
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Martin H. Cohen, Huanyu Chen, Stacy Shord, Chana Fuchs, Kun He, Hong Zhao, Sharon Sickafuse, Patricia Keegan & Richard Pazdur. (2013) Approval Summary: Cetuximab in Combination With Cisplatin or Carboplatin and 5-Fluorouracil for the First-Line Treatment of Patients With Recurrent Locoregional or Metastatic Squamous Cell Head and Neck Cancer. The Oncologist 18:4, pages 460-466.
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Katherine R. Singleton, Jihye Kim, Trista K. Hinz, Lindsay A. Marek, Matias Casás-Selves, Clark Hatheway, Aik Choon Tan, James DeGregori & Lynn E. Heasley. (2013) A Receptor Tyrosine Kinase Network Composed of Fibroblast Growth Factor Receptors, Epidermal Growth Factor Receptor, v-erb-b2 Erythroblastic Leukemia Viral Oncogene Homolog 2, and Hepatocyte Growth Factor Receptor Drives Growth and Survival of Head and Neck Squamous Carcinoma Cell Lines. Molecular Pharmacology 83:4, pages 882-893.
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Amy Grimsley, Katherine S. Shah & Trevor McKibbin. 2013. Pharmaceutical Biotechnology. Pharmaceutical Biotechnology 337 359 .
Kathleen N. Moore, Michael W. Sill, David S. Miller, Carolyn McCourt, Koen De Geest, Peter G. Rose, Higinia R. Cardenes, Robert S. Mannel, John H. Farley, Russell J. Schilder & Paula M. Fracasso. (2012) A phase I trial of tailored radiation therapy with concomitant cetuximab and cisplatin in the treatment of patients with cervical cancer: A gynecologic oncology group study. Gynecologic Oncology 127:3, pages 456-461.
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Ingvild J. Brusevold, Monica Aasrum, Magne Bryne & Thoralf Christoffersen. (2012) Migration induced by epidermal and hepatocyte growth factors in oral squamous carcinoma cells in vitro : role of MEK/ERK, p38 and PI‐3 kinase/Akt . Journal of Oral Pathology & Medicine 41:7, pages 547-558.
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Theresa L. Whiteside, Lisa H. Butterfield, Paul H. Naylor, James E. Egan, John W. Hadden, Lorraine Baltzer, Gregory T. Wolf & Neil L. Berinstein. (2011) A short course of neoadjuvant IRX-2 induces changes in peripheral blood lymphocyte subsets of patients with head and neck squamous cell carcinoma. Cancer Immunology, Immunotherapy 61:6, pages 783-788.
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GUANG-HUI LI, BO ZHU, FAN YANG, CHUAN-KUN MA & DING-QIANG YANG. (2012) Use of cetuximab in combination with pulsed reduced dose-rate radiotherapy in a patient with recurrence of nasopharyngeal carcinoma in the neck. Experimental and Therapeutic Medicine 3:5, pages 869-872.
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MARTIN LEINUNG, DANIEL HIRTH, AYKUT TAHTALI, MARC DIENSTHUBER, TIMO STÖVER & JENS WAGENBLAST. (2012) Fighting cancer from different signalling pathways: Effects of the proteasome inhibitor Bortezomib in combination with the polo-like-kinase-1-inhibitor BI2536 in SCCHN. Oncology Letters 4:6, pages 1305-1308.
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D.I. Pryor, E. Burmeister, B.H. Burmeister, M.G. Poulsen & S.V. Porceddu. (2011) Distinct patterns of stomatitis with concurrent cetuximab and radiotherapy for head and neck squamous cell carcinoma. Oral Oncology 47:10, pages 984-987.
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Marianne E. Marshall, Trista K. Hinz, Scott A. Kono, Katherine R. Singleton, Brady Bichon, Kathryn E. Ware, Lindsay Marek, Barbara A. Frederick, David Raben & Lynn E. Heasley. (2011) Fibroblast Growth Factor Receptors Are Components of Autocrine Signaling Networks in Head and Neck Squamous Cell Carcinoma Cells. Clinical Cancer Research 17:15, pages 5016-5025.
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