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Expert Review of Anticancer Therapy Volume 12, 2012 - Issue 12
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Theme: Kidney Cancer - Review

Sequential therapy in metastatic clear cell renal carcinoma: TKI–TKI vs TKI–mTOR

Alessandra Felici Division of Medical Oncology A, Regina Elena National Cancer Institute,Via Elio Chianesi 53, 00144, Rome, Italy; Division of Medical Oncology A, Regina Elena National Cancer Institute,Via Elio Chianesi 53, 00144, Rome, Italy
,
Emilio Bria Medical Oncology dU, Azienda Ospedaliera Universitaria Integrata, University of Verona, Policlinico ‘G.B. Rossi’, Verona, Italy; Medical Oncology dU, Azienda Ospedaliera Universitaria Integrata, University of Verona, Policlinico ‘G.B. Rossi’, Verona, Italy
,
Giampaolo Tortora Medical Oncology dU, Azienda Ospedaliera Universitaria Integrata, University of Verona, Policlinico ‘G.B. Rossi’, Verona, Italy; Medical Oncology dU, Azienda Ospedaliera Universitaria Integrata, University of Verona, Policlinico ‘G.B. Rossi’, Verona, Italy
,
Francesco Cognetti Division of Medical Oncology A, Regina Elena National Cancer Institute,Via Elio Chianesi 53, 00144, Rome, Italy; Division of Medical Oncology A, Regina Elena National Cancer Institute,Via Elio Chianesi 53, 00144, Rome, Italy
&
Michele Milella Division of Medical Oncology A, Regina Elena National Cancer Institute,Via Elio Chianesi 53, 00144, Rome, Italy; Division of Medical Oncology A, Regina Elena National Cancer Institute,Via Elio Chianesi 53, 00144, Rome, Italy. [email protected]
Pages 1545-1557 | Published online: 10 Jan 2014

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Sumanta K. Pal, Eric Jonasch, James E. Signorovitch, William M. Reichmann, Nanxin Li, Zhimei Liu, Jose Ricardo Perez & Nicholas J. Vogelzang. (2016) Real-world dosing and drug costs with everolimus or axitinib as second targeted therapies for advanced renal cell carcinoma: a retrospective chart review in the US. Journal of Medical Economics 19:5, pages 462-468.
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James E. Signorovitch, Nicholas J. Vogelzang, Sumanta K. Pal, Peggy L. Lin, Daniel J. George, Michael K. Wong, Zhimei Liu, Xufang Wang, Ken Culver, Jeffrey A. Scott & Eric Jonasch. (2014) Comparative effectiveness of second-line targeted therapies for metastatic renal cell carcinoma: synthesis of findings from two multi-practice chart reviews in the United States. Current Medical Research and Opinion 30:11, pages 2343-2353.
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Matteo Santoni, Michele De Tursi, Alessandra Felici, Giovanni Lo Re, Riccardo Ricotta, Enzo Maria Ruggeri, Roberto Sabbatini, Daniele Santini, Vanja Vaccaro & Michele Milella. (2013) Management of metastatic renal cell carcinoma patients with poor-risk features: current status and future perspectives. Expert Review of Anticancer Therapy 13:6, pages 697-709.
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Articles from other publishers (10)

Wasiu Opeyemi Oduola, Xiangfang L. Li, Chang Duan, Lijun Qian & Edward R. Dougherty. (2018) Sequential Therapeutic Response Modeling for Tumor Treatment Using Computational Hybrid Control Systems Approach. IEEE Transactions on Biomedical Engineering 65:4, pages 866-874.
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Wasiu Opeyemi Oduola, Xiangfang Li, Chang Duan, Lijun Qian, Fen Wu & Edward R Dougherty. (2017) Time-Based Switching Control of Genetic Regulatory Networks: Toward Sequential Drug Intake for Cancer Therapy. Cancer Informatics 16, pages 117693511770688.
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Victor C. Kok & Jung-Tsung Kuo. (2016) Pazopanib as a second-line treatment for non-cytokine-treated metastatic renal cell carcinoma: a meta-analysis of the effect of treatment. BMC Urology 16:1.
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Julio Lambea, Urbano Anido, Olatz Etxániz, Luis Flores, Álvaro Montesa, Juan Manuel Sepúlveda & Emilio Esteban. (2016) The Wide Experience of the Sequential Therapy for Patients with Metastatic Renal Cell Carcinoma. Current Oncology Reports 18:11.
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Michele Milella. (2016) Optimizing clinical benefit with targeted treatment in mRCC: “Tumor growth rate” as an alternative clinical endpoint. Critical Reviews in Oncology/Hematology 102, pages 73-81.
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R. Elaidi, A. Harbaoui, B. Beuselinck, J.-C. Eymard, A. Bamias, E. De Guillebon, C. Porta, Y. Vano, C. Linassier, P.R. Debruyne, M. Gross-Goupil, A. Ravaud, M. Aitelhaj, G. Marret & S. Oudard. (2015) Outcomes from second-line therapy in long-term responders to first-line tyrosine kinase inhibitor in clear-cell metastatic renal cell carcinoma. Annals of Oncology 26:2, pages 378-385.
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Aaron B. Cohen & Marcia S. Brose. (2014) Second-Line Treatment for Advanced Thyroid Cancer: An Indication in Need of Randomized Clinical Trials. The Journal of Clinical Endocrinology & Metabolism 99:6, pages 1995-1997.
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Manuela Schmidinger. (2014) Improving Outcomes in Metastatic Clear Cell Renal Cell Carcinoma by Sequencing Therapy. American Society of Clinical Oncology Educational Book:34, pages e228-e238.
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Giuseppe Di Lorenzo & Sabino De Placido. (2014) Using cumulative toxicity to identify the optimal second-line targeted therapy in patients with metastatic renal cell carcinoma: what’s new?. Future Oncology 10:5, pages 845-850.
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R Rosa, V Damiano, L Nappi, L Formisano, F Massari, A Scarpa, G Martignoni, R Bianco & G Tortora. (2013) Angiogenic and signalling proteins correlate with sensitivity to sequential treatment in renal cell cancer. British Journal of Cancer 109:3, pages 686-693.
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