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Theme: Brain/Neurologic - Review

Molecular mechanisms of temozolomide resistance in glioblastoma multiforme

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Pages 635-642 | Published online: 10 Jan 2014

Keep up to date with the latest research on this topic with citation updates for this article.

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Jianglong Xu, Jia Song, Menglin Xiao, Changsheng Wang, Qisong Zhang, Xiaoye Yuan & Shaohui Tian. (2021) RUNX1 (RUNX family transcription factor 1), a target of microRNA miR-128-3p, promotes temozolomide resistance in glioblastoma multiform by upregulating multidrug resistance-associated protein 1 (MRP1). Bioengineered 12:2, pages 11768-11781.
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Ming Ji, Liyuan Wang, Ju Chen, Nina Xue, Chunyang Wang, Fangfang Lai, Rubing Wang, Shishan Yu, Jing Jin & Xiaoguang Chen. (2018) CAT3, a prodrug of 13a(S)-3-hydroxyl-6,7-dimethoxyphenanthro[9,10-b]-indolizidine, circumvents temozolomide-resistant glioblastoma via the Hedgehog signaling pathway, independently of O6-methylguanine DNA methyltransferase expression. OncoTargets and Therapy 11, pages 3671-3684.
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R. J. Head, M. F. Fay, L. Cosgrove, K. Y. C. Fung, D. Rundle-Thiele & J. H. Martin. (2017) Persistence of DNA adducts, hypermutation and acquisition of cellular resistance to alkylating agents in glioblastoma. Cancer Biology & Therapy 18:12, pages 917-926.
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Tao Song, Hui Li, Zhiliang Tian, Chaojiu Xu, Jingfang Liu & Yong Guo. (2015) Disruption of NF-κB signaling by fluoxetine attenuates MGMT expression in glioma cells. OncoTargets and Therapy 8, pages 2199-2208.
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Barbara Banelli, Elisa Carra, Federica Barbieri, Roberto Würth, Federica Parodi, Alessandra Pattarozzi, Roberta Carosio, Alessandra Forlani, Giorgio Allemanni, Daniela Marubbi, Tullio Florio, Antonio Daga & Massimo Romani. (2015) The histone demethylase KDM5A is a key factor for the resistance to temozolomide in glioblastoma. Cell Cycle 14:21, pages 3418-3429.
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