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Clinical Trial Report

Safety of inhibition of cholesteryl ester transfer protein with anacetrapib: the DEFINE study

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Pages 955-963 | Published online: 10 Jan 2014

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Jing Pang, Dick C Chan & Gerald F Watts. (2014) Critical review of non-statin treatments for dyslipoproteinemia. Expert Review of Cardiovascular Therapy 12:3, pages 359-371.
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Venkat R. Chirasani & Sanjib Senapati. (2017) How cholesteryl ester transfer protein can also be a potential triglyceride transporter. Scientific Reports 7:1.
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Venkat R. Chirasani, Prasanna D. Revanasiddappa & Sanjib Senapati. (2016) Structural Plasticity of Cholesteryl Ester Transfer Protein Assists the Lipid Transfer Activity. Journal of Biological Chemistry 291:37, pages 19462-19473.
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Dongsheng Lei, Matthew Rames, Xing Zhang, Lei Zhang, Shengli Zhang & Gang Ren. (2016) Insights into the Tunnel Mechanism of Cholesteryl Ester Transfer Protein through All-atom Molecular Dynamics Simulations. Journal of Biological Chemistry 291:27, pages 14034-14044.
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Mostafa Jamalan, Majid Zeinali & Mohammad Ali Ghaffari. (2015) A molecular dynamics investigation on the inhibition mechanism of cholesteryl ester transfer protein by Anacetrapib. Medicinal Chemistry Research 25:1, pages 62-69.
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J Lu, Y Cleary, C Maugeais, CI Kiu Weber & NA Mazer. (2015) Analysis of “On/Off” Kinetics of a CETP Inhibitor Using a Mechanistic Model of Lipoprotein Metabolism and Kinetics. CPT: Pharmacometrics & Systems Pharmacology 4:8, pages 465-473.
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Mohammed Al-Hijji, Seth S. Martin, Parag H. Joshi & Steven R. Jones. (2013) Effect of Equivalent On-Treatment Apolipoprotein Levels on Outcomes (from the AIM-HIGH and HPS2-THRIVE). The American Journal of Cardiology 112:10, pages 1697-1700.
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