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Review

Newer antifungal agents

Pages 325-338 | Published online: 10 Jan 2014

Keep up to date with the latest research on this topic with citation updates for this article.

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Ioannis Kyriakidis, Athanasios Tragiannidis, Silke Munchen & Andreas H. Groll. (2017) Clinical hepatotoxicity associated with antifungal agents. Expert Opinion on Drug Safety 16:2, pages 149-165.
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Maria N Chitasombat & Dimitrios P Kontoyiannis. (2015) The ‘cephalosporin era’ of triazole therapy: isavuconazole, a welcomed newcomer for the treatment of invasive fungal infections. Expert Opinion on Pharmacotherapy 16:10, pages 1543-1558.
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Seyedmojtaba Seyedmousavi, Paul E Verweij & Johan W Mouton. (2015) Isavuconazole, a broad-spectrum triazole for the treatment of systemic fungal diseases. Expert Review of Anti-infective Therapy 13:1, pages 9-27.
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Athanasios Tragiannidis, Christos Tsoulas, Kornelius Kerl & Andreas H Groll. (2013) Invasive candidiasis: update on current pharmacotherapy options and future perspectives. Expert Opinion on Pharmacotherapy 14:11, pages 1515-1528.
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Ener Cagri Dinleyici. (2011) Pediatric invasive fungal infections: realities, challenges, concerns, myths and hopes. Expert Review of Anti-infective Therapy 9:3, pages 273-274.
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Soukaina Bouamrane, Ayoub Khaldan, Halima Hajji, Reda El-mernissi, Marwa Alaqarbeh, Nada Alsakhen, Hamid Maghat, Mohammed Aziz Ajana, Abdelouahid Sbai, Mohammed Bouachrine & Tahar Lakhlifi. (2022) In silico identification of 1,2,4-triazoles as potential Candida Albicans inhibitors using 3D-QSAR, molecular docking, molecular dynamics simulations, and ADMET profiling. Molecular Diversity.
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Dovilė Malūkaitė, Birutė Grybaitė, Rita Vaickelionienė, Giedrius Vaickelionis, Birutė Sapijanskaitė-Banevič, Povilas Kavaliauskas & Vytautas Mickevičius. (2021) Synthesis of Novel Thiazole Derivatives Bearing β-Amino Acid and Aromatic Moieties as Promising Scaffolds for the Development of New Antibacterial and Antifungal Candidates Targeting Multidrug-Resistant Pathogens. Molecules 27:1, pages 74.
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Saraswathi Nagaraj, Sivakami Manivannan & Shoba Narayan. (2021) Potent antifungal agents and use of nanocarriers to improve delivery to the infected site: A systematic review. Journal of Basic Microbiology 61:10, pages 849-873.
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Donald J. AbrahamSeyedmojtaba Seyedmousavi. 2003. Burger's Medicinal Chemistry and Drug Discovery. Burger's Medicinal Chemistry and Drug Discovery 1 62 .
Rocio Garcia-Rubio, Maria C. Monteiro & Emilia Mellado. 2021. Encyclopedia of Mycology. Encyclopedia of Mycology 427 437 .
Zichao Ding, Tingjunhong Ni, Fei Xie, Yumeng Hao, Shichong Yu, Xiaoyun Chai, Yongsheng Jin, Ting Wang, Yuanying Jiang & Dazhi Zhang. (2020) Design, synthesis, and structure-activity relationship studies of novel triazole agents with strong antifungal activity against Aspergillus fumigatus. Bioorganic & Medicinal Chemistry Letters 30:4, pages 126951.
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M. A. Pfaller, M. D. Huband, R. K. Flamm, P. A. Bien & M. Castanheira. (2019) In Vitro Activity of APX001A (Manogepix) and Comparator Agents against 1,706 Fungal Isolates Collected during an International Surveillance Program in 2017 . Antimicrobial Agents and Chemotherapy 63:8.
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Matthew W. McCarthy, Brad Moriyama, Ruta Petraitiene, Thomas J. Walsh & Vidmantas Petraitis. (2018) Clinical Pharmacokinetics and Pharmacodynamics of Isavuconazole. Clinical Pharmacokinetics 57:12, pages 1483-1491.
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Bin Sun, Hong Zhang, Min Liu, Zhuang Hou & Xinyong Liu. (2018) Structure-based virtual screening and ADME/T-based prediction analysis for the discovery of novel antifungal CYP51 inhibitors. MedChemComm 9:7, pages 1178-1187.
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Maria Cristina Ghezzi, Grazia Brunetti, Valeria Visconti, Alessandra Giordano & Giammarco Raponi. (2017) Candidaemia in a tertiary care academic hospital in Italy. The impact of C. parapsilosis complex on the species distribution and antifungal susceptibility. Journal of Medical Microbiology 66:7, pages 990-998.
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Bin Sun, Wanxu Huang & Min Liu. (2017) Evaluation of the combination mode of azoles antifungal inhibitors with CACYP51 and the influence of Site-directed mutation. Journal of Molecular Graphics and Modelling 73, pages 157-165.
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Hai-Jiang Chen, Yan-Juan Jiang, Yong-Qiang Zhang, Qi-Wei Jing, Na Liu, Yan Wang, Wan-Nian Zhang & Chun-Quan Sheng. (2017) New triazole derivatives containing substituted 1,2,3-triazole side chains: Design, synthesis and antifungal activity. Chinese Chemical Letters 28:4, pages 913-918.
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Seyedmojtaba Seyedmousavi, Haleh Rafati, Macit Ilkit, Ali Tolooe, Mohammad T. Hedayati & Paul Verweij. 2017. Human Fungal Pathogen Identification. Human Fungal Pathogen Identification 107 139 .
Sukhbir K Shahid. (2016) Newer patents in antimycotic therapy. Pharmaceutical Patent Analyst 5:2, pages 115-134.
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Martin Pouliot & Stephane Jeanmart. (2015) Pan Assay Interference Compounds (PAINS) and Other Promiscuous Compounds in Antifungal Research. Journal of Medicinal Chemistry 59:2, pages 497-503.
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Hideyo Yamaguchi. (2016) Potential of Ravuconazole and its Prodrugs as the New OralTherapeutics for Onychomycosis. Medical Mycology Journal 57:4, pages E93-E110.
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Ruben Vardanyan & Victor Hruby. 2016. Synthesis of Best-Seller Drugs. Synthesis of Best-Seller Drugs 677 686 .
Xufeng Cao, Yuanyuan Xu, Yongbing Cao, Ruilian Wang, Ran Zhou, Wenjing Chu & Yushe Yang. (2015) Design, synthesis, and structure–activity relationship studies of novel thienopyrrolidone derivatives with strong antifungal activity against Aspergillus fumigates. European Journal of Medicinal Chemistry 102, pages 471-476.
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Brunella Posteraro, Teresa Spanu, Barbara Fiori, Flavio De Maio, Elena De Carolis, Alessia Giaquinto, Valentina Prete, Giulia De Angelis, Riccardo Torelli, Tiziana D'Inzeo, Antonietta Vella, Alessio De Luca, Mario Tumbarello, Walter Ricciardi & Maurizio Sanguinetti. (2015) Antifungal Susceptibility Profiles of Bloodstream Yeast Isolates by Sensititre YeastOne over Nine Years at a Large Italian Teaching Hospital. Antimicrobial Agents and Chemotherapy 59:7, pages 3944-3955.
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Ebidor U Lawani, Tolulope Alade & Godbless Pelessai. (2015) The mycological content of ready to eat garri in Amassoma, Bayelsa State. African Journal of Food Science 9:2, pages 51-58.
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Xiaomeng He, Yan Jiang, Yongqiang Zhang, Shanchao Wu, Guoqiang Dong, Na Liu, Yang Liu, Jianzhong Yao, Zhenyuan Miao, Yan Wang, Wannian Zhang & Chunquan Sheng. (2015) Discovery of highly potent triazoleantifungal agents with piperidine-oxadiazole side chains. MedChemComm 6:4, pages 653-664.
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Shanchao Wu, Yongqiang Zhang, Xiaomeng He, Xiaoying Che, Shengzheng Wang, Yang Liu, Yan Jiang, Na Liu, Guoqiang Dong, Jianzhong Yao, Zhenyuan Miao, Yan Wang, Wannian Zhang & Chunquan Sheng. (2014) From Antidiabetic to Antifungal: Discovery of Highly Potent Triazole–Thiazolidinedione Hybrids as Novel Antifungal Agents. ChemMedChem 9:12, pages 2639-2646.
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Brunella Posteraro & Maurizio Sanguinetti. (2014) The future of fungal susceptibility testing. Future Microbiology 9:8, pages 947-967.
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Zhigan Jiang, Julin Gu, Chen Wang, Shengzheng Wang, Na Liu, Yan Jiang, Guoqiang Dong, Yan Wang, Yang Liu, Jianzhong Yao, Zhenyuan Miao, Wannian Zhang & Chunquan Sheng. (2014) Design, synthesis and antifungal activity of novel triazole derivatives containing substituted 1,2,3-triazole-piperdine side chains. European Journal of Medicinal Chemistry 82, pages 490-497.
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Xufeng Cao, Zhaoshuan Sun, Yongbing Cao, Ruilian Wang, Tongkai Cai, Wenjing Chu, Wenhao Hu & Yushe Yang. (2014) Design, Synthesis, and Structure–Activity Relationship Studies of Novel Fused Heterocycles-Linked Triazoles with Good Activity and Water Solubility. Journal of Medicinal Chemistry 57:9, pages 3687-3706.
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Adrine Innocente, Bruna B. Casanova, Fernanda Klein, Aline D. Lana, Dariane Pereira, Mauro N. Muniz, Pascal Sonnet, Grace Gosmann, Alexandre M. Fuentefria & Simone C. B. Gnoatto. (2014) Synthesis of Isosteric Triterpenoid Derivatives and Antifungal Activity. Chemical Biology & Drug Design 83:3, pages 344-349.
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Josiane Helou, Grace Obeid, Roy Moutran & Ismael Maatouk. (2014) Pityriasis versicolor: a case of resistance to treatment. International Journal of Dermatology 53:2, pages e114-e116.
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Maria Fernanda Reis Gavazzoni Dias, Fred Bernardes-Filho, Maria Victória Pinto Quaresma-Santos, Adriana Gutstein da Fonseca Amorim, Regina Casz SchechtmanDavid Rubem Azulay. (2013) Treatment of superficial mycoses: review - part II. Anais Brasileiros de Dermatologia 88:6, pages 937-944.
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Camila Di Giovane Costanzo, Vanessa Colnaghi Fernandes, Sônia Zingaretti, Rene Oliveira Beleboni, Ana Maria Soares Pereira, Mozart Marins, Sílvia Helena Taleb-Contini, Paulo Sérgio Pereira & Ana Lúcia Fachin. (2013) Isolation of flavonoids from Anemopaegma arvense (Vell) Stellf. ex de Souza and their antifungal activity against Trichophyton rubrum. Brazilian Journal of Pharmaceutical Sciences 49:3, pages 559-565.
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Brunella Posteraro, Patrizia Posteraro & Maurizio Sanguinetti. (2013) Update on Antifungal Resistance and its Clinical Impact. Current Fungal Infection Reports 7:3, pages 224-234.
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Rémi Guillon, Fabrice Pagniez, Carine Picot, Damien Hédou, Alain Tonnerre, Elizabeth Chosson, Muriel Duflos, Thierry Besson, Cédric Logé & Patrice Le Pape. (2013) Discovery of a Novel Broad-Spectrum Antifungal Agent Derived from Albaconazole. ACS Medicinal Chemistry Letters 4:2, pages 288-292.
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Beatriz Larru & Theoklis E. Zaoutis. (2013) Newer antifungal agents. Current Opinion in Pediatrics 25:1, pages 110-115.
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Alejandro Díaz & Carlos Garcés. (2012) Uso actual de los antifúngicos triazoles en niños. Infectio 16, pages 82-93.
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Rémi Guillon, Fabrice Pagniez, Charlotte Rambaud, Carine Picot, Muriel Duflos, Cédric Logé & Patrice Le Pape. (2011) Design, Synthesis, and Biological Evaluation of 1-[(Biarylmethyl)methylamino]-2-(2,4-difluorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ols as Potent Antifungal Agents: New Insights into Structure-Activity Relationships. ChemMedChem 6:10, pages 1806-1815.
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