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Review

Antibacterial oxazolidinones: emerging structure–toxicity relationships

Pages 565-574 | Published online: 10 Jan 2014

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Yewon Choi, Sang Won Lee, Anhye Kim, Kyungho Jang, Heesook Nam, Young Lag Cho, Kyung-Sang Yu, In-Jin Jang & Jae-Yong Chung. (2018) Safety, tolerability and pharmacokinetics of 21 day multiple oral administration of a new oxazolidinone antibiotic, LCB01-0371, in healthy male subjects. Journal of Antimicrobial Chemotherapy 73:1, pages 183-190.
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Khuloud Takrouri, Harold D. Cooper, Andrew Spaulding, Paola Zucchi, Bilyana Koleva, Dillon C. Cleary, Westley Tear, Penny J. Beuning, Elizabeth B. Hirsch & James B. Aggen. (2016) Progress against Escherichia coli with the Oxazolidinone Class of Antibacterials: Test Case for a General Approach To Improving Whole-Cell Gram-Negative Activity . ACS Infectious Diseases 2:6, pages 405-426.
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Tao Yang, Gong Chen, Zitai Sang, Yuanyuan Liu, Xiaoyan Yang, Ying Chang, Haiyue Long, Wei Ang, Jianying Tang, Zhenling Wang, Guobo Li, Shengyong Yang, Jingren Zhang, Yuquan Wei & Youfu Luo. (2015) Discovery of a Teraryl Oxazolidinone Compound ( S )- N -((3-(3-Fluoro-4-(4-(pyridin-2-yl)-1 H -pyrazol-1-yl)phenyl)-2-oxooxazolidin-5-yl)methyl)acetamide Phosphate as a Novel Antimicrobial Agent with Enhanced Safety Profile and Efficacies . Journal of Medicinal Chemistry 58:16, pages 6389-6409.
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Xiaoyan Yang, Zicheng Li, Zhenling Wang, Zitai Sang, Haiyue Long, Jianying Tang, Tao Yang, Yuanyuan Liu & Youfu Luo. (2015) Synthesis and antibacterial activity evaluation of C-5 side chain modified analogues of FYL-66, a potential agent against methicillin-resistant Staphylococcus aureus. MedChemComm 6:6, pages 1156-1172.
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