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Drug Profile

Elvitegravir: a once-daily, boosted, HIV-1 integrase inhibitor

Pages 13-20 | Published online: 10 Jan 2014

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Stefano Bonora, Andrea Calcagno, Alice Trentalange & Giovanni Di Perri. (2016) Elvitegravir, cobicistat, emtricitabine and tenofovir alafenamide for the treatment of HIV in adults. Expert Opinion on Pharmacotherapy 17:3, pages 409-419.
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Andrea R. Thurman, Louise A. Ouattara, Nazita Yousefieh, Peter L. Anderson, Lane R. Bushman, Xi Fang, Homaira Hanif, Meredith Clark, Onkar Singh & Gustavo F. Doncel. (2023) A phase I study to assess safety, pharmacokinetics, and pharmacodynamics of a vaginal insert containing tenofovir alafenamide and elvitegravir. Frontiers in Cellular and Infection Microbiology 13.
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Hao-Wei Chu, Bidyadhar Sethy, Pei-Wen Hsieh & Jim-Tong Horng. (2021) Identification of Potential Drug Targets of Broad-Spectrum Inhibitors with a Michael Acceptor Moiety Using Shotgun Proteomics. Viruses 13:9, pages 1756.
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Rajaiah Alexpandi, Joelma Freire De Mesquita, Shunmugiah Karutha Pandian & Arumugam Veera Ravi. (2020) Quinolines-Based SARS-CoV-2 3CLpro and RdRp Inhibitors and Spike-RBD-ACE2 Inhibitor for Drug-Repurposing Against COVID-19: An in silico Analysis. Frontiers in Microbiology 11.
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Minal R. Ghante, Akash C. Masale, Supriya G. Jagtap, Sanjay D. Sawant & Vandana S. Nikam. (2020) SIMPLE, COST EFFECTIVE UV-VIS METHOD FOR ESTIMATION OF ELVITEGRAVIR (EVG) IN PURE AND DOSAGE FORM BY QBD APPROACH AND IN PRESENCE OF MAMMALIAN PLASMA. INDIAN DRUGS 57:01, pages 51-58.
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Bum Sik Chin, Jin-Hee Lee & Gayeon Kim. (2020) Similar Durability of Two Single Tablet Regimens, Dolutegravir/Abacavir/Lamivudine and Elvitegravir/Cobicistat/Tenofovir/Emtricitabine: Single Center Experience. Journal of Korean Medical Science 35:29.
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Umesh Panwar, Ishwar Chandra, Chandrabose Selvaraj & Sanjeev K. Singh. (2019) Current Computational Approaches for the Development of Anti-HIV Inhibitors: An Overview. Current Pharmaceutical Design 25:31, pages 3390-3405.
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Derek E. Murrell, David B. Cluck, Jonathan P. Moorman, Stacy D. Brown, Ke-Sheng Wang, Michelle M. Duffourc & Sam Harirforoosh. (2019) HIV Integrase Inhibitor Pharmacogenetics: An Exploratory Study. Clinical Drug Investigation 39:3, pages 285-299.
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Muneeb Mohideen, Elias Quijano, Eric Song, Yang Deng, Gauri Panse, Wei Zhang, Meredith R. Clark & W. Mark Saltzman. (2017) Degradable bioadhesive nanoparticles for prolonged intravaginal delivery and retention of elvitegravir. Biomaterials 144, pages 144-154.
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Mark G.J. de Boer, Guido E.L. van den Berk, Natasja van Holten, Josephine E. Oryszcyn, Willemien Dorama, Daoud ait Moha & Kees Brinkman. (2016) Intolerance of dolutegravir-containing combination antiretroviral therapy regimens in real-life clinical practice. AIDS 30:18, pages 2831-2834.
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Nicole L. De La Mata, David A. Cooper, Darren Russell, Don Smith, Ian Woolley, Maree O. Sullivan, Stephen Wright & Matthew Law. (2016) Treatment durability and virological response in treatment-experienced HIV-positive patients on an integrase inhibitor-based regimen: an Australian cohort study. Sexual Health 13:4, pages 335.
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Tomas Doyle, David T. Dunn, Francesca Ceccherini-Silberstein, Carmen De Mendoza, Frederico Garcia, Erasmus Smit, Esther Fearnhill, Anne-Genevieve Marcelin, Javier Martinez-Picado, Rolf Kaiser & Anna Maria Geretti. (2015) Integrase inhibitor (INI) genotypic resistance in treatment-naive and raltegravir-experienced patients infected with diverse HIV-1 clades. Journal of Antimicrobial Chemotherapy 70:11, pages 3080-3086.
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Mitalee Tamhane, Manoj Maniar, Chen Ren, Kenza E. Benzeroual & David R. Taft. (2013) Disposition of ON 01210.Na (Ex-RAD(R)), a Novel Radioprotectant, in the Isolated Perfused Rat Liver: Probing Metabolic Inhibition to Increase Systemic Exposure. Journal of Pharmaceutical Sciences 102:2, pages 732-740.
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Miłosz Parczewski, Dorota Bander, Anna Urbańska & Anna Boroń-Kaczmarska. (2012) HIV-1 integrase resistance among antiretroviral treatment naive and experienced patients from Northwestern Poland. BMC Infectious Diseases 12:1.
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Anna Maria Geretti, Daniele Armenia & Francesca Ceccherini-Silberstein. (2012) Emerging patterns and implications of HIV-1 integrase inhibitor resistance. Current Opinion in Infectious Diseases 25:6, pages 677-686.
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Erik M. van MaarseveenChristin C. RogersJennifer Trofe-ClarkArjan D. van ZuilenTania Mudrikova. (2012) Drug–Drug Interactions Between Antiretroviral and Immunosuppressive Agents in HIV-Infected Patients After Solid Organ Transplantation: A Review. AIDS Patient Care and STDs 26:10, pages 568-581.
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Liming Hu, Song Yan, Zaigang Luo, Xiao Han, Yujie Wang, Zhanyang Wang & Chengchu Zeng. (2012) Design, Practical Synthesis, and Biological Evaluation of Novel 6-(Pyrazolylmethyl)-4-quinoline-3-carboxylic Acid Derivatives as HIV-1 Integrase Inhibitors. Molecules 17:9, pages 10652-10666.
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