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Tarig B Higazi, Timothy G Geary & Charles D Mackenzie. (2014) Chemotherapy in the treatment, control, and elimination of human onchocerciasis. Research and Reports in Tropical Medicine 5, pages 77-93.
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Charles D Mackenzie & Timothy G Geary. (2013) Addressing the current challenges to finding new anthelminthic drugs. Expert Review of Anti-infective Therapy 11:6, pages 539-541.
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Francesca Fata, Radosveta Gencheva, Qing Cheng, Rachel Lullo, Matteo Ardini, Ilaria Silvestri, Federica Gabriele, Rodolfo Ippoliti, Christina A. Bulman, Judy A. Sakanari, David L. Williams, Elias S.J. Arnér & Francesco Angelucci. (2022) Biochemical and structural characterizations of thioredoxin reductase selenoproteins of the parasitic filarial nematodes Brugia malayi and Onchocerca volvulus. Redox Biology 51, pages 102278.
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Ole Lagatie, Emmanuel Njumbe Ediage, Dirk Van Roosbroeck, Stijn Van Asten, Ann Verheyen, Linda Batsa Debrah, Alex Debrah, Maurice R. Odiere, Ruben T’Kindt, Emmie Dumont, Koen Sandra, Lieve Dillen, Tom Verhaeghe, Rob Vreeken, Filip Cuyckens & Lieven J. Stuyver. (2021) Multimodal biomarker discovery for active Onchocerca volvulus infection. PLOS Neglected Tropical Diseases 15:11, pages e0009999.
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Germanus S. Bah, Sebastian Schneckener, Steffen R. Hahnel, Nicolas H. Bayang, Helena Fieseler, Gabriele M. Schmuck, Ralph Krebber, Anouk Sarr, Carsten Terjung, Henrietta F. Ngangyung, David D. Ekale, Youssouf M. Mfopit, Lucien Rufener, John Graham-Brown, Vincent N. Tanya, Martin Glenschek-Sieberth, Daniel Kulke & Benjamin L. Makepeace. (2021) Emodepside targets SLO-1 channels of Onchocerca ochengi and induces broad anthelmintic effects in a bovine model of onchocerciasis. PLOS Pathogens 17:6, pages e1009601.
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Marc P. Hübner, Coralie Martin, Sabine Specht, Marianne Koschel, Bettina Dubben, Stefan J. Frohberger, Alexandra Ehrens, Martina Fendler, Dominique Struever, Edward Mitre, Nathaly Vallarino-Lhermitte, Suzanne Gokool, Sara Lustigman, Manfred Schneider, Simon Townson, Achim Hoerauf & Ivan Scandale. (2020) Oxfendazole mediates macrofilaricidal efficacy against the filarial nematode Litomosoides sigmodontis in vivo and inhibits Onchocerca spec. motility in vitro. PLOS Neglected Tropical Diseases 14:7, pages e0008427.
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Fanny Fri Fombad, Abdel Jelil Njouendou, Patrick Chounna Ndongmo, Manuel Ritter, Valerine C. Chunda, Haelly M. Metuge, Narcisse Victor T. Gandjui, Peter Enyong, Flobert Njiokou, Achim Hoerauf, Charles D. Mackenzie & Samuel Wanji. (2019) Effect of flubendazole on developing stages of Loa loa in vitro and in vivo: a new approach for screening filaricidal agents. Parasites & Vectors 12:1.
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Nicolas P. Pionnier, Hanna Sjoberg, Valerine C. Chunda, Fanny F. Fombad, Patrick W. Chounna, Abdel J. Njouendou, Haelly M. Metuge, Bertrand L. Ndzeshang, Narcisse V. Gandjui, Desmond N. Akumtoh, Dizzle B. Tayong, Mark J. Taylor, Samuel Wanji & Joseph D. Turner. (2019) Mouse models of Loa loa. Nature Communications 10:1.
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Denis Voronin, Nancy Tricoche, Shabnam Jawahar, Michael Shlossman, Christina A. Bulman, Chelsea Fischer, Michael T. Suderman, Judy A. Sakanari & Sara Lustigman. (2019) Development of a preliminary in vitro drug screening assay based on a newly established culturing system for pre-adult fifth-stage Onchocerca volvulus worms. PLOS Neglected Tropical Diseases 13:1, pages e0007108.
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Timothy G. Geary, Charles D. Mackenzie & Steven A. Silber. (2019) Flubendazole as a macrofilaricide: History and background. PLOS Neglected Tropical Diseases 13:1, pages e0006436.
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Hanna T. Sjoberg, Nicolas Pionnier, Ghaith Aljayyoussi, Haelly M. Metuge, Abdel J. Njouendou, Valerine C. Chunda, Fanny F. Fombad, Dizzle B. Tayong, Narcisse V. T. Gandjui, Desmond N. Akumtoh, Patrick W. N. Chounna, Bertrand L. Ndzeshang, Sophie Lachaud, Fetene Tekle, Ludo Quirynen, Marc Engelen, Benny Baeten, Andrew Steven, Stephen A. Ward, Mark J. Taylor, Samuel Wanji & Joseph D. Turner. (2019) Short-course, oral flubendazole does not mediate significant efficacy against Onchocerca adult male worms or Brugia microfilariae in murine infection models. PLOS Neglected Tropical Diseases 13:1, pages e0006356.
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Marc P. Hübner, Alexandra Ehrens, Marianne Koschel, Bettina Dubben, Franziska Lenz, Stefan J. Frohberger, Sabine Specht, Ludo Quirynen, Sophie Lachau-Durand, Fetene Tekle, Benny Baeten, Marc Engelen, Charles D. Mackenzie & Achim Hoerauf. (2019) Macrofilaricidal efficacy of single and repeated oral and subcutaneous doses of flubendazole in Litomosoides sigmodontis infected jirds. PLOS Neglected Tropical Diseases 13:1, pages e0006320.
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Mamta Gangwar, Ruchi Jha, Manish Goyal & Mrigank Srivastava. (2019) Immunogenicity and protective efficacy of Recombinase A from Wolbachia endosymbiont of filarial nematode Brugia malayi (wBmRecA). Vaccine 37:4, pages 571-580.
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Lukyn M. Gedge, Alison A. Bettis, Mark H. Bradley, T. Déirdre Hollingsworth & Hugo C. Turner. (2018) Economic evaluations of lymphatic filariasis interventions: a systematic review and research needs. Parasites & Vectors 11:1.
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Belinda M. Jackson-Thompson, So Young Kim, Shalini Jaiswal, Jessica R. Scott, Scott R. Jones, C. Paul Morris, J. Judd Fite, Karen Laurie, Andrew R. Hoy, Bernard J. Dardzinski & Edward Mitre. (2018) Brugia malayi infection in ferrets – A small mammal model of lymphatic filariasis. PLOS Neglected Tropical Diseases 12:3, pages e0006334.
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Vito Colella, Carla Maia, André Pereira, Nuno Gonçalves, Marta Caruso, Coralie Martin, Luís Cardoso, Lenea Campino, Ivan Scandale & Domenico Otranto. (2018) Evaluation of oxfendazole in the treatment of zoonotic Onchocerca lupi infection in dogs. PLOS Neglected Tropical Diseases 12:1, pages e0006218.
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Lisa J Reimer, Emily R Adams, Mark JI Paine, Hilary Ranson, Marlize Coleman, Edward K Thomsen, Eleanor E MacPherson, T Deirdre Hollingsworth, Louise A Kelly-Hope, Moses J Bockarie, Louise Ford, Robert A Harrison, J Russell Stothard, Mark J Taylor, Nicholas Hamon & Stephen J Torr. (2015) Fit for purpose: do we have the right tools to sustain NTD elimination?. BMC Proceedings 9:S10.
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Dwight D. Bowman, Samuel D. Charles, Robert G. Arther & Terry Settje. (2015) Laboratory Evaluation of the Efficacy of 10 % Imidacloprid + 2.5 % Moxidectin Topical Solution (Advantage® Multi, Advocate®) for the Treatment of Dirofilaria immitis Circulating Microfilariae in Dogs. Parasitology Research 114:S1, pages 165-174.
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Timothy G. Geary, Judy A. Sakanari & Conor R. Caffrey. (2015) Anthelmintic Drug Discovery: Into the Future. Journal of Parasitology 101:2, pages 125-133.
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Peter J. Hotez, Maria Elena Bottazzi, Bin Zhan, Benjamin L. Makepeace, Thomas R. Klei, David Abraham, David W. Taylor & Sara Lustigman. (2015) The Onchocerciasis Vaccine for Africa—TOVA—Initiative. PLOS Neglected Tropical Diseases 9:1, pages e0003422.
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Monica Longo, Sara Zanoncelli, Monica Messina, Ivan Scandale, Charles Mackenzie, Timothy Geary, Kennan Marsh, David Lindley & Guy Mazué. (2014) In vivo preliminary investigations of the effects of the benzimidazole anthelmintic drug flubendazole on rat embryos and fetuses. Reproductive Toxicology 49, pages 33-42.
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Kwablah Awadzi, Nicholas O. Opoku, Simon K. Attah, Janis Lazdins-Helds & Annette C. Kuesel. (2014) A Randomized, Single-Ascending-Dose, Ivermectin-Controlled, Double-Blind Study of Moxidectin in Onchocerca volvulus Infection. PLoS Neglected Tropical Diseases 8:6, pages e2953.
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Monica Longo, Sara Zanoncelli, Paolo Angelo Colombo, Michael Oscar Harhay, Ivan Scandale, Charles Mackenzie, Timothy Geary, Nicole Madrill & Guy Mazué. (2013) Effects of the benzimidazole anthelmintic drug flubendazole on rat embryos in vitro. Reproductive Toxicology 36, pages 78-87.
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Christian S. Lentz, Victoria Halls, Jeffrey S. Hannam, Björn Niebel, Uta Strübing, Günter Mayer, Achim Hoerauf, Michael Famulok & Kenneth M. Pfarr. (2013) A Selective Inhibitor of Heme Biosynthesis in Endosymbiotic Bacteria Elicits Antifilarial Activity In Vitro. Chemistry & Biology 20:2, pages 177-187.
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Daniel Kulke, Jürgen Krücken, Janina Demeler, Achim Harder, Heinz Mehlhorn & Georg von Samson-Himmelstjerna. (2012) In vitro efficacy of cyclooctadepsipepdtides and aminophenylamidines alone and in combination against third-stage larvae and adult worms of Nippostrongylus brasiliensis and first-stage larvae of Trichinella spiralis. Parasitology Research 112:1, pages 335-345.
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Timothy G. Geary. (2012) Are new anthelmintics needed to eliminate human helminthiases?. Current Opinion in Infectious Diseases 25:6, pages 709-717.
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Jürgen Krücken, Achim Harder, Peter Jeschke, Lindy Holden-Dye, Vincent O’Connor, Claudia Welz & Georg von Samson-Himmelstjerna. (2012) Anthelmintic cyclooctadepsipeptides: complex in structure and mode of action. Trends in Parasitology 28:9, pages 385-394.
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Timothy G. Geary, Kelly Chibale, Berhanu Abegaz, Kerstin Andrae-Marobela & Eliane Ubalijoro. (2012) A new approach for anthelmintic discovery for humans. Trends in Parasitology 28:5, pages 176-181.
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Chris Marcellino, Jiri Gut, K. C. Lim, Rahul Singh, James McKerrow & Judy Sakanari. (2012) WormAssay: A Novel Computer Application for Whole-Plate Motion-based Screening of Macroscopic Parasites. PLoS Neglected Tropical Diseases 6:1, pages e1494.
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