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Expert Review of Anti-infective Therapy Volume 10, 2012 - Issue 10
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Review

Toxoplasma histone acetylation remodelers as novel drug targets

Laura Vanagas Laboratorio de Parasitología Molecular, IIB-INTECH, CONICET-UNSAM, Av. Intendente Marino Km. 8.2, C.C 164, (B7130IIWA), Chascomús, Prov. Buenos Aires, Argentina. [email protected]; Laboratorio de Parasitología Molecular, IIB-INTECH, CONICET-UNSAM, Av. Intendente Marino Km. 8.2, C.C 164, (B7130IIWA), Chascomús, Prov. Buenos Aires, Argentina
,
Victoria Jeffers Pharmacology & Toxicology, Indiana University School of Medicine, Indianapolis, IN 46202, USA;; Pharmacology & Toxicology, Indiana University School of Medicine, Indianapolis, IN 46202, USA;
,
Silvina S Bogado Laboratorio de Parasitología Molecular, IIB-INTECH, CONICET-UNSAM, Av. Intendente Marino Km. 8.2, C.C 164, (B7130IIWA), Chascomús, Prov. Buenos Aires, Argentina; Laboratorio de Parasitología Molecular, IIB-INTECH, CONICET-UNSAM, Av. Intendente Marino Km. 8.2, C.C 164, (B7130IIWA), Chascomús, Prov. Buenos Aires, Argentina
,
Maria C Dalmasso Laboratorio de Parasitología Molecular, IIB-INTECH, CONICET-UNSAM, Av. Intendente Marino Km. 8.2, C.C 164, (B7130IIWA), Chascomús, Prov. Buenos Aires, Argentina; Laboratorio de Parasitología Molecular, IIB-INTECH, CONICET-UNSAM, Av. Intendente Marino Km. 8.2, C.C 164, (B7130IIWA), Chascomús, Prov. Buenos Aires, Argentina
,
William J Sullivan Jr Pharmacology & Toxicology, Indiana University School of Medicine, Indianapolis, IN 46202, USA;; Microbiology & Immunology, Indiana University School of Medicine, Indianapolis, IN 46202, USA; Pharmacology & Toxicology, Indiana University School of Medicine, Indianapolis, IN 46202, USA;; Microbiology & Immunology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
&
Sergio O Angel Laboratorio de Parasitología Molecular, IIB-INTECH, CONICET-UNSAM, Av. Intendente Marino Km. 8.2, C.C 164, (B7130IIWA), Chascomús, Prov. Buenos Aires, Argentina; Laboratorio de Parasitología Molecular, IIB-INTECH, CONICET-UNSAM, Av. Intendente Marino Km. 8.2, C.C 164, (B7130IIWA), Chascomús, Prov. Buenos Aires, Argentina
Pages 1189-1201 | Published online: 10 Jan 2014

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Joachim Müller & Andrew Hemphill. (2023) Toxoplasma gondii infection: novel emerging therapeutic targets. Expert Opinion on Therapeutic Targets 27:4-5, pages 293-304.
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Manasi Sawant, Sadia Benamrouz-Vanneste, Dionigia Meloni, Nausicaa Gantois, Gaël Even, Karine Guyot, Colette Creusy, Erika Duval, René Wintjens, Jonathan B. Weitzman, Magali Chabe, Eric Viscogliosi & Gabriela Certad. (2022) Putative SET-domain methyltransferases in Cryptosporidium parvum and histone methylation during infection. Virulence 13:1, pages 1632-1650.
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P Holland Alday & Joseph Stone Doggett. (2017) Drugs in development for toxoplasmosis: advances, challenges, and current status. Drug Design, Development and Therapy 11, pages 273-293.
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Suzanne Wahab, Alejandro Saettone, Syed Nabeel-Shah, Nora Dannah & Jeffrey Fillingham. (2020) Exploring the Histone Acetylation Cycle in the Protozoan Model Tetrahymena thermophila. Frontiers in Cell and Developmental Biology 8.
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Genevieve Syn, Jenefer M Blackwell, Sarra E Jamieson & Richard W Francis. (2018) An in silico pipeline to filter the Toxoplasma gondii proteome for proteins that could traffic to the host cell nucleus and influence host cell epigenetic regulation. Memórias do Instituto Oswaldo Cruz 113:6.
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Mahbobeh Montazeri, Mehdi Sharif, Shahabeddin Sarvi, Saeed Mehrzadi, Ehsan Ahmadpour & Ahmad Daryani. (2017) A Systematic Review of In vitro and In vivo Activities of Anti-Toxoplasma Drugs and Compounds (2006–2016). Frontiers in Microbiology 8.
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Madalyn M. McFarland, Sydney J. Zach, Xiaofang Wang, Lakshmi-Prasad Potluri, Andrew J. Neville, Jonathan L. Vennerstrom & Paul H. Davis. (2016) Review of Experimental Compounds Demonstrating Anti-Toxoplasma Activity. Antimicrobial Agents and Chemotherapy 60:12, pages 7017-7034.
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A. Ropolo & M.C. Touz. 2016. Chromatin Signaling and Diseases. Chromatin Signaling and Diseases 347 363 .
Rasha F. Mady, Wessam El-Hadidy & Samar Elachy. (2015) Effect of Nigella sativa oil on experimental toxoplasmosis. Parasitology Research 115:1, pages 379-390.
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SERGIO O. ANGEL, MARIA J. FIGUERAS, MARIA L. ALOMAR, PABLO C. ECHEVERRIA & BIN DENG. (2014) Toxoplasma gondii Hsp90: potential roles in essential cellular processes of the parasite . Parasitology 141:9, pages 1138-1147.
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Maria L Alomar, Federico AO Rasse-Suriani, Agustina Ganuza, Verónica M Cóceres, Franco M Cabrerizo & Sergio O Angel. (2013) In vitro evaluation of β-carboline alkaloids as potential anti-Toxoplasma agents. BMC Research Notes 6:1.
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Krista L. Stilger & William J. SullivanJr.Jr.. (2013) Elongator Protein 3 (Elp3) Lysine Acetyltransferase Is a Tail-anchored Mitochondrial Protein in Toxoplasma gondii. Journal of Biological Chemistry 288:35, pages 25318-25329.
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