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Expert Review of Molecular Diagnostics Volume 12, 2012 - Issue 6
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Review

Multiplexed nucleic acid-based assays for molecular diagnostics of human disease

Alina Deshpande Decision Applications Division, Mail Stop C936, Los Alamos National Laboratory, Los Alamos, NM 87545, USA. [email protected]
&
Paul Scott White Bioscience Division, Mail Stop M888, Los Alamos National Laboratory, Los Alamos, NM 87545, USA
Pages 645-659 | Published online: 09 Jan 2014

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Roberto Gambari. (2014) Peptide nucleic acids: a review on recent patents and technology transfer. Expert Opinion on Therapeutic Patents 24:3, pages 267-294.
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Yuliang Kang, Jiali Wang, Wensi Zhang, Yuhang Xu, Bohui Xu, Guangbo Qu, Yanyan Yu, Bing Yan & Gaoxing Su. (2023) RNA extraction-free workflow integrated with a single-tube CRISPR-Cas-based colorimetric assay for rapid SARS-CoV-2 detection in different environmental matrices. Journal of Hazardous Materials 454, pages 131487.
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Yoon Ho Roh, Chang Yeol Lee, Sujin Lee, Hyunho Kim, Amy Ly, Cesar M. Castro, Jinwoo Cheon, Jae‐Hyun Lee & Hakho Lee. (2023) CRISPR‐Enhanced Hydrogel Microparticles for Multiplexed Detection of Nucleic Acids. Advanced Science 10:10.
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Anindya Dutta, Nilanjan Banerjee, Madhurima Chaudhuri & Subhrangsu Chatterjee. 2023. Nucleic Acid Biology and its Application in Human Diseases. Nucleic Acid Biology and its Application in Human Diseases 213 269 .
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Semyung Jung, Ki Wan Bong & Wonhwi Na. (2022) Multiplex Assay for Rapid Detection and Analysis of Nucleic Acid Using Barcode Receptor Encoded Particle (BREP). Biomedicines 10:12, pages 3246.
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Zhejia Gu, Tong Sun, Qingsheng Guo, Yao Wang, Yunfei Ge, Hongchen Gu, Gaolian Xu & Hong Xu. (2022) Bead-Based Multiplexed Droplet Digital Polymerase Chain Reaction in a Single Tube Using Universal Sequences: An Ultrasensitive, Cross-Reaction-Free, and High-Throughput Strategy. ACS Sensors 7:9, pages 2759-2766.
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Min Li, Fangfei Yin, Lu Song, Xiuhai Mao, Fan Li, Chunhai Fan, Xiaolei Zuo & Qiang Xia. (2021) Nucleic Acid Tests for Clinical Translation. Chemical Reviews 121:17, pages 10469-10558.
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Mohamed A. Abdou Mohamed, Hannah N. Kozlowski, Jisung Kim, Kyryl Zagorovsky, Melinda Kantor, Jordan J. Feld, Samira Mubareka, Tony Mazzulli & Warren C. W. Chan. (2021) Diagnosing Antibiotic Resistance Using Nucleic Acid Enzymes and Gold Nanoparticles. ACS Nano 15:6, pages 9379-9390.
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Nireshni Mitchev, Ravesh Singh, Nigel Garrett, Veron Ramsuran, Abraham J. Niehaus & Koleka P. Mlisana. (2021) Performance of TaqMan probes for the detection of sexually transmitted infections in South African women. African Journal of Laboratory Medicine 10:1.
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Mi Yeon Kim, Seungwon Jung, Junsun Kim, Heon Jeong Lee, Seunghwa Jeong, Sang Jun Sim & Sang Kyung Kim. (2021) Highly sensitive and multiplexed one-step RT-qPCR for profiling genes involved in the circadian rhythm using microparticles. Scientific Reports 11:1.
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Fengge Song, Yuanyuan Shen, Yangdao Wei, Chunrong Yang, Xiaolin Ge, Aimin Wang, Chaoyang Li, Yi Wan & Jinghong Li. (2021) Botulinum toxin as an ultrasensitive reporter for bacterial and SARS-CoV-2 nucleic acid diagnostics. Biosensors and Bioelectronics 176, pages 112953.
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Yong‐Tae Kim, Junhye Moon & In Seok Hong. (2020) Simultaneous Detection of Multiple Pathogenic Targets with Stem‐Tagged Primer Sets. ChemBioChem 21:8, pages 1116-1120.
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Kinza Hasham, Naveed Ahmed & Basit Zeshan. (2020) Circulating microRNAs in oncogenic viral infections: potential diagnostic biomarkers. SN Applied Sciences 2:3.
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Yueshuang Xu, Huan Wang, Baoan Chen, Hong Liu & Yuanjin Zhao. (2018) Emerging barcode particles for multiplex bioassays基于新兴编码微载体的多元生物检测. Science China Materials 62:3, pages 289-324.
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Chao Wang, Shengzhou Wang, Hongyan Chen & Daru Lu. (2018) Establishment of a Gene Detection System for Hotspot Mutations of Hearing Loss. BioMed Research International 2018, pages 1-8.
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Hadi Ravan, Mojdeh Amandadi & Saeed Esmaeili-Mahani. (2017) DNA Domino-Based Nanoscale Logic Circuit: A Versatile Strategy for Ultrasensitive Multiplexed Analysis of Nucleic Acids. Analytical Chemistry 89:11, pages 6021-6028.
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Jinzhao Song, Changchun Liu, Michael G Mauk, Shelley C Rankin, James B Lok, Robert M Greenberg & Haim H Bau. (2017) Two-Stage Isothermal Enzymatic Amplification for Concurrent Multiplex Molecular Detection. Clinical Chemistry 63:3, pages 714-722.
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Weiwei Xu, Chao Chen, Xiaodong Ma, Lihua Yuan, Shenquan Liu, Kexiao Zheng & Jiong Li. (2017) Digitally encoded silica microparticles for multiplexed nucleic acid detection. Chemical Communications 53:43, pages 5866-5869.
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Y. Ma, X. Dai, T. Hong, G. B. Munk & M. Libera. (2017) A NASBA on microgel-tethered molecular-beacon microarray for real-time microbial molecular diagnostics. The Analyst 142:1, pages 147-155.
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A. Deshpande & P.S. White. 2017. Molecular Diagnostics. Molecular Diagnostics 327 337 .
Travis A. Woods, Heather M. Mendez, Sandy Ortega, Xiaorong Shi, David Marx, Jianfa Bai, Rodney A. Moxley, T. G. Nagaraja, Steven W. Graves & Alina Deshpande. (2016) Development of 11-Plex MOL-PCR Assay for the Rapid Screening of Samples for Shiga Toxin-Producing Escherichia coli. Frontiers in Cellular and Infection Microbiology 6.
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Alina Deshpande, Benjamin McMahon, Ashlynn R. Daughton, Esteban L. Abeyta, David Hodge, Kevin Anderson & Segaran Pillai. (2016) Surveillance for Emerging Diseases with Multiplexed Point-of-Care Diagnostics. Health Security 14:3, pages 111-121.
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Seungwon Jung, Junsun Kim, Dong Jin Lee, Eun Hae Oh, Hwasup Lim, Kwang Pyo Kim, Nakwon Choi, Tae Song Kim & Sang Kyung Kim. (2016) Extensible Multiplex Real-time PCR of MicroRNA Using Microparticles. Scientific Reports 6:1.
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Friedrich Schuler, Martin Trotter, Roland Zengerle & Felix von Stetten. (2016) Monochrome Multiplexing in Polymerase Chain Reaction by Photobleaching of Fluorogenic Hydrolysis Probes. Analytical Chemistry 88:5, pages 2590-2595.
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A. Lehmusvuori, M. Soikkeli, E. Tuunainen, T. Seppä, A. Spangar, K. Rantakokko-Jalava, P. von Lode, U. Karhunen, T. Soukka & S. Wittfooth. (2015) Ready to use dry-reagent PCR assays for the four common bacterial pathogens using switchable lanthanide luminescence probe system. Journal of Microbiological Methods 118, pages 64-69.
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Soledad Carinelli, Mercè Martí, Salvador Alegret & María Isabel Pividori. (2015) Biomarker detection of global infectious diseases based on magnetic particles. New Biotechnology 32:5, pages 521-532.
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Yi‐Chen Yang, Der‐Yuan Wang, Hwei‐Fang Cheng, Eric Y. Chuang & Mong‐Hsun Tsai. (2014) A reliable multiplex genotyping assay for HCV using a suspension bead array . Microbial Biotechnology 8:1, pages 93-102.
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Julia Engstrom-Melnyk, Pedro L. Rodriguez, Olivier Peraud & Raymond C. Hein. 2015. Current and Emerging Technologies for the Diagnosis of Microbial Infections. Current and Emerging Technologies for the Diagnosis of Microbial Infections 161 197 .
John‐Stephen Taylor. 2014. Nanotechnology for Biomedical Imaging and Diagnostics. Nanotechnology for Biomedical Imaging and Diagnostics 373 400 .
Maria Mallén, María Díaz-González, Diana Bonilla, Juan P. Salvador, María P. Marco, Antoni Baldi & César Fernández-Sánchez. (2014) Reusable conductimetric array of interdigitated microelectrodes for the readout of low-density microarrays. Analytica Chimica Acta 832, pages 44-50.
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María Díaz-González, Xavier Muñoz-Berbel, Cecilia Jiménez-Jorquera, Antoni Baldi & César Fernández-Sánchez. (2014) Diagnostics Using Multiplexed Electrochemical Readout Devices. Electroanalysis 26:6, pages 1154-1170.
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Xiaoguang Dai & Matthew Libera. (2014) Dip-pen microarraying of molecular beacon probes on microgel thin-film substrates. The Analyst 139:21, pages 5568-5575.
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Yiqun Liao, Xiaobo Wang, Chao Sha, Zhongmin Xia, Qiuying Huang & Qingge Li. (2013) Combination of fluorescence color and melting temperature as a two-dimensional label for homogeneous multiplex PCR detection. Nucleic Acids Research 41:7, pages e76-e76.
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