Advanced search
Publication Cover
Expert Review of Neurotherapeutics Volume 9, 2009 - Issue 6
Submit an article Journal homepage
61
Views
30
CrossRef citations to date
0
Altmetric
Review

Development of the calcium plateau following status epilepticus: role of calcium in epileptogenesis

Nisha Nagarkatti Departments of Neurology and Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, VA 23298, USA. [email protected]
,
Laxmikant S Deshpande Department of Neurology, Virginia Commonwealth University, Richmond, VA 23298, USA. [email protected]
&
Robert J DeLorenzo Departments of Neurology, Pharmacology and Toxicology, and Molecular Biophysics and Biochemistry, Virginia Commonwealth University, School of Medicine, PO Box 980599, Richmond, VA 23298, USA. [email protected]
Pages 813-824 | Published online: 09 Jan 2014

Citations (30)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Hua Yu, Xuelian Yang, Xu Tang & Renkuan Tang. (2018) Effects of spontaneous recurrent seizures on cognitive function via modulation of SNAREs expression. International Journal of Neuroscience 128:4, pages 376-383.
Read now

Articles from other publishers (29)

Evgeny S. Nikitin, Tatiana Y. Postnikova, Elena Y. Proskurina, Anastasia A. Borodinova, Violetta Ivanova, Matvey V. Roshchin, Maria P. Smirnova, Ilya Kelmanson, Vsevolod V. Belousov, Pavel M. Balaban & Aleksey V. Zaitsev. (2023) Overexpression of KCNN4 channels in principal neurons produces an anti-seizure effect without reducing their coding ability. Gene Therapy.
Crossref
Yuan Li, Bingxing Shuai, Jia Liu & Lan Wu. (2023) Propofol inducedseizure-like phenomena: A case report and literature review. Asian Journal of Surgery.
Crossref
Thaarvena Retinasamy & Mohd. Farooq Shaikh. 2023. Handbook of Neurodegenerative Disorders. Handbook of Neurodegenerative Disorders 1 15 .
Marios Charalambous, Sofie F.M. Bhatti, Holger A. Volk & Simon Platt. (2022) Defining and overcoming the therapeutic obstacles in canine refractory status epilepticus. The Veterinary Journal 283-284, pages 105828.
Crossref
Dmitry V. Amakhin, Elena B. Soboleva, Anton V. Chizhov & Aleksey V. Zaitsev. (2021) Insertion of Calcium-Permeable AMPA Receptors during Epileptiform Activity In Vitro Modulates Excitability of Principal Neurons in the Rat Entorhinal Cortex. International Journal of Molecular Sciences 22:22, pages 12174.
Crossref
Rodrigo Ribeiro dos Santos, Túlio C. Bernardino, Maria Carolina Machado da Silva, Antônio C.P. de Oliveira, Luciana E. Drumond, Daniela V. Rosa, André R. Massensini, Márcio F.D. Moraes, Maria C. Doretto, Marco A. Romano-Silva & Helton J. Reis. (2021) Neurochemical abnormalities in the hippocampus of male rats displaying audiogenic seizures, a genetic model of epilepsy. Neuroscience Letters 761, pages 136123.
Crossref
Shima Khodaverdian, Elahe Dashtban-Moghadam, Bahareh Dabirmanesh, Javad Mirnajafi-Zadeh, Mohammad Taleb, Khosro Khajeh & Yaghoub Fathollahi. (2021) CD38 and MGluR1 as possible signaling molecules involved in epileptogenesis: A potential role for NAD+ homeostasis. Brain Research 1765, pages 147509.
Crossref
Miranda Mele, Ricardo Vieira, Bárbara Correia, Pasqualino De Luca, Filipe V. Duarte, Paulo S. Pinheiro & Carlos B. Duarte. (2021) Transient incubation of cultured hippocampal neurons in the absence of magnesium induces rhythmic and synchronized epileptiform-like activity. Scientific Reports 11:1.
Crossref
Pablo M. Casillas‐Espinosa, Idrish Ali & Terence J. O'Brien. (2020) Neurodegenerative pathways as targets for acquired epilepsy therapy development. Epilepsia Open 5:2, pages 138-154.
Crossref
Kristin F Phillips & Laxmikant S Deshpande. (2020) Calcium Hypothesis of Gulf War Illness: Role of Calcium Ions in Neurological Morbidities in a DFP-Based Rat Model for Gulf War Illness. Neuroscience Insights 15, pages 263310552097984.
Crossref
Laxmikant S. Deshpande & Robert J. DeLorenzo. (2020) Novel therapeutics for treating organophosphate-induced status epilepticus co-morbidities, based on changes in calcium homeostasis. Neurobiology of Disease 133, pages 104418.
Crossref
Pablo M. Casillas-Espinosa, Sandy R. Shultz, Emma L. Braine, Nigel C. Jones, Terrance P. Snutch, Kim L. Powell & Terence J. O’Brien. (2019) Disease-modifying effects of a novel T-type calcium channel antagonist, Z944, in a model of temporal lobe epilepsy. Progress in Neurobiology 182, pages 101677.
Crossref
Kristin F Phillips, Edna Santos, Robert E Blair & Laxmikant S Deshpande. (2019) Targeting Intracellular Calcium Stores Alleviates Neurological Morbidities in a DFP-Based Rat Model of Gulf War Illness. Toxicological Sciences 169:2, pages 567-578.
Crossref
Patricia G. Saletti, Idrish Ali, Pablo M. Casillas-Espinosa, Bridgette D. Semple, Christos Panagiotis Lisgaras, Solomon L. Moshé & Aristea S. Galanopoulou. (2019) In search of antiepileptogenic treatments for post-traumatic epilepsy. Neurobiology of Disease 123, pages 86-99.
Crossref
Kristin F. Phillips, Laxmikant S. Deshpande & Robert J. DeLorenzo. (2018) Hypothermia Reduces Mortality, Prevents the Calcium Plateau, and Is Neuroprotective Following Status Epilepticus in Rats. Frontiers in Neurology 9.
Crossref
Suchitra Joshi, Karthik Rajasekaran, John Williamson & Jaideep Kapur. (2017) Neurosteroid‐sensitive δ‐GABA A receptors: A role in epileptogenesis? . Epilepsia 58:3, pages 494-504.
Crossref
Laxmikant S. Deshpande, Robert E. Blair, Kristin F. Phillips & Robert J. DeLorenzo. (2016) Role of the calcium plateau in neuronal injury and behavioral morbidities following organophosphate intoxication. Annals of the New York Academy of Sciences 1374:1, pages 176-183.
Crossref
Tamara K. Berdyyeva, E. Paxon Frady, Jonathan J. Nassi, Leah Aluisio, Yauheniya Cherkas, Stephani Otte, Ryan M. Wyatt, Christine Dugovic, Kunal K. Ghosh, Mark J. Schnitzer, Timothy Lovenberg & Pascal Bonaventure. (2016) Direct Imaging of Hippocampal Epileptiform Calcium Motifs Following Kainic Acid Administration in Freely Behaving Mice. Frontiers in Neuroscience 10.
Crossref
Zeynep Selen Karalok, Ebru Petek Arhan, Kadri Murat Erdogan & Esra Gurkas. (2015) Excellent response to levetiracetam in epilepsy with Wolf-Hirschhorn syndrome. Child's Nervous System 32:1, pages 9-11.
Crossref
Frederic Dorandeu, Franck Dhote, Laure Barbier, Benjamin Baccus & Guy Testylier. (2013) Treatment of Status Epilepticus with Ketamine, Are we There yet?. CNS Neuroscience & Therapeutics 19:6, pages 411-427.
Crossref
Roberto Di Maio, Pier G. Mastroberardino, Xiaoping Hu, Laura M. Montero & J. Timothy Greenamyre. (2013) Thiol oxidation and altered NR2B/NMDA receptor functions in in vitro and in vivo pilocarpine models: Implications for epileptogenesis. Neurobiology of Disease 49, pages 87-98.
Crossref
Dongman Chao & Ying Xia. 2013. Current Research in Acupuncture. Current Research in Acupuncture 129 214 .
Karthik Rajasekaran, Marko Todorovic & Jaideep Kapur. (2012) Calcium‐permeable AMPA receptors are expressed in a rodent model of status epilepticus. Annals of Neurology 72:1, pages 91-102.
Crossref
Carlotta Giorgi, Chiara Agnoletto, Angela Bononi, Massimo Bonora, Elena De Marchi, Saverio Marchi, Sonia Missiroli, Simone Patergnani, Federica Poletti, Alessandro Rimessi, Jan M. Suski, Mariusz R. Wieckowski & Paolo Pinton. (2012) Mitochondrial calcium homeostasis as potential target for mitochondrial medicine. Mitochondrion 12:1, pages 77-85.
Crossref
Roberto Di Maio, Pier G. Mastroberardino, Xiaoping Hu, Laura Montero & J. Timothy Greenamyre. (2011) Pilocapine alters NMDA receptor expression and function in hippocampal neurons: NADPH oxidase and ERK1/2 mechanisms. Neurobiology of Disease 42:3, pages 482-495.
Crossref
Gregor ZündorfGeorg Reiser. (2011) Calcium Dysregulation and Homeostasis of Neural Calcium in the Molecular Mechanisms of Neurodegenerative Diseases Provide Multiple Targets for Neuroprotection. Antioxidants & Redox Signaling 14:7, pages 1275-1288.
Crossref
Laxmikant S. Deshpande, Dawn S. Carter, Robert E. Blair & Robert J. DeLorenzo. (2010) Development of a Prolonged Calcium Plateau in Hippocampal Neurons in Rats Surviving Status Epilepticus Induced by the Organophosphate Diisopropylfluorophosphate. Toxicological Sciences 116:2, pages 623-631.
Crossref
Nisha Nagarkatti, Laxmikant S. Deshpande, Dawn S. Carter & Robert J. DeLorenzo. (2010) Dantrolene inhibits the calcium plateau and prevents the development of spontaneous recurrent epileptiform discharges following in vitro status epilepticus . European Journal of Neuroscience 32:1, pages 80-88.
Crossref
Dwayne W GodwinJohn D Graef. (2009) A rising tide of calcium channels in acquired epilepsy. Future Neurology 4:6, pages 679-682.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.