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Editorial

Is there a rationale for cortisol-based treatments for PTSD?

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Pages 1113-1115 | Published online: 09 Jan 2014

Keep up to date with the latest research on this topic with citation updates for this article.

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Annie M. Whitaker, Muhammad A. Farooq, Scott Edwards & Nicholas W. Gilpin. (2016) Post-traumatic stress avoidance is attenuated by corticosterone and associated with brain levels of steroid receptor co-activator-1 in rats. Stress 19:1, pages 69-77.
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Atle Dyregrov & Stephen Regel. (2012) Early Interventions Following Exposure to Traumatic Events: Implications for Practice From Recent Research. Journal of Loss and Trauma 17:3, pages 271-291.
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Articles from other publishers (21)

Mesud Sarmanlu, Kim P.C. Kuypers, Patrick Vizeli & Timo L. Kvamme. (2024) MDMA-assisted psychotherapy for PTSD: Growing evidence for memory effects mediating treatment efficacy. Progress in Neuro-Psychopharmacology and Biological Psychiatry 128, pages 110843.
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Qian Yu, Ka-Kit Wong, On-Kei Lei, Jinlei Nie, Qingde Shi, Liye Zou & Zhaowei Kong. (2022) Comparative Effectiveness of Multiple Exercise Interventions in the Treatment of Mental Health Disorders: A Systematic Review and Network Meta-Analysis. Sports Medicine - Open 8:1.
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Sabra S. Inslicht, Andrea N. Niles, Thomas J. Metzler, Sa’ar L. Lipshitz, Christian Otte, Mohammed R. Milad, Scott P. Orr, Charles R. Marmar & Thomas C. Neylan. (2021) Randomized controlled experimental study of hydrocortisone and D-cycloserine effects on fear extinction in PTSD. Neuropsychopharmacology 47:11, pages 1945-1952.
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Tongli Zhang & John J. Tyson. (2022) Understanding virtual patients efficiently and rigorously by combining machine learning with dynamical modelling. Journal of Pharmacokinetics and Pharmacodynamics 49:1, pages 117-131.
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Lin Zhu, Long Li, Xiao-zhi Li & Lin Wang. (2022) Mind–Body Exercises for PTSD Symptoms, Depression, and Anxiety in Patients With PTSD: A Systematic Review and Meta-Analysis. Frontiers in Psychology 12.
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Reza Yakhkeshi, Fatemeh Roshani, Kobra Akhoundzadeh & Sakineh Shafia. (2022) Effect of treadmill exercise on serum corticosterone, serum and hippocampal BDNF, hippocampal apoptosis and anxiety behavior in an ovariectomized rat model of post-traumatic stress disorder (PTSD). Physiology & Behavior 243, pages 113629.
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Lin Zhu, Long Li, Xiao-zhi Li & Lin Wang. (2021) Effects of mind-body exercise on PTSD symptoms, depression and anxiety in PTSD patients. Medicine 100:4, pages e24447.
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Marieke J. van Gelderen, Mirjam J. Nijdam, Friso de Vries, Onno C. Meijer & Eric Vermetten. (2020) Exposure-related cortisol predicts outcome of psychotherapy in veterans with treatment-resistant posttraumatic stress disorder. Journal of Psychiatric Research 130, pages 387-393.
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Jonathan DePierro, Lauren Lepow, Adriana Feder & Rachel Yehuda. (2019) Translating Molecular and Neuroendocrine Findings in Posttraumatic Stress Disorder and Resilience to Novel Therapies. Biological Psychiatry 86:6, pages 454-463.
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Jessica L. Maples-Keller, Tanja Jovanovic, Boadie W. Dunlop, Sheila Rauch, Carly Yasinski, Vasiliki Michopoulos, Callan Coghlan, Seth Norrholm, Albert Skip Rizzo, Kerry Ressler & Barbara O. Rothbaum. (2019) When translational neuroscience fails in the clinic: Dexamethasone prior to virtual reality exposure therapy increases drop-out rates. Journal of Anxiety Disorders 61, pages 89-97.
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Konstantinos Papazoglou. (2017) Examining the Psychophysiological Efficacy of CBT Treatment for First Responders Diagnosed With PTSD: An Understudied Topic. SAGE Open 7:3, pages 215824401772940.
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Christine F. Schubert, Ulrike Schmidt & Rita Rosner. (2016) Posttraumatic Growth in Populations with Posttraumatic Stress Disorder-A Systematic Review on Growth-Related Psychological Constructs and Biological Variables. Clinical Psychology & Psychotherapy 23:6, pages 469-486.
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Wilfrid Noel Raby, Lisa SanFilippo, Martina Pavlicova, Kenneth M. Carpenter, Andrew Glass, Chukwudi Onyemekwu, Eric Roginek & Edward V. Nunes. (2014) Dysregulation of Diurnal Cortisol Secretion Affects Abstinence Induction during a Lead-in Period of a Clinical Trial for Depressed Cocaine-Dependent Patients. The American Journal on Addictions 23:1, pages 1-6.
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Sang Hwan KimSuzanne M. Schneider, Margaret BevansLen Kravitz, Christine Mermier, Clifford Qualls & Mark R. Burge. (2013) PTSD Symptom Reduction With Mindfulness-Based Stretching and Deep Breathing Exercise: Randomized Controlled Clinical Trial of Efficacy. The Journal of Clinical Endocrinology & Metabolism 98:7, pages 2984-2992.
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Nicole R. Nugent, Michelle A. Lally, Larry Brown, Valerie S. Knopik & John E. McGeary. (2011) OPRM1 and Diagnosis-Related Posttraumatic Stress Disorder in Binge-Drinking Patients Living with HIV. AIDS and Behavior 16:8, pages 2171-2180.
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Rachel Yehuda & Jonathan Seckl. (2011) Minireview: Stress-Related Psychiatric Disorders with Low Cortisol Levels: A Metabolic Hypothesis. Endocrinology 152:12, pages 4496-4503.
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Katja Wingenfeld & Oliver T. Wolf. (2011) HPA Axis Alterations in Mental Disorders: Impact on Memory and its Relevance for Therapeutic Interventions. CNS Neuroscience & Therapeutics 17:6, pages 714-722.
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Akaysha C. Tang, Huan Jiang, Zhen Yang, Ying Zhang, Russell D. Romeo & Bruce S. McEwen. (2011) Converging influence of neonatal novelty experience and maternal self-stress regulation on the plasticity of offspring acoustic startle response latency. Behavioural Brain Research 221:1, pages 253-260.
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Rhonda Board & Jianyu Dai. (2011) Effects of five parent-and-child risk factors on salivary cortisol levels and symptoms of posttraumatic stress disorder in school-age, critically ill children: Pilot study. Heart & Lung 40:3, pages 236-246.
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Nicolas Rohleder, Jutta M. Wolf & Oliver T. Wolf. (2010) Glucocorticoid sensitivity of cognitive and inflammatory processes in depression and posttraumatic stress disorder. Neuroscience & Biobehavioral Reviews 35:1, pages 104-114.
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Michael R. Trimble & Mark S. George. 2010. Biological Psychiatry. Biological Psychiatry 335 393 .

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