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Expert Review of Neurotherapeutics Volume 11, 2011 - Issue 11
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Theme: Pain - Review

Optimizing the early phase development of new analgesics by human pain biomarkers

Lars Arendt-Nielsen Center for Sensory–Motor Interaction, Department of Health Sciences and Technology, Laboratory for Experimental Pain Research, Aalborg University, Fredrik Bajers Vej 7 D3, DK-9220, Aalborg, Denmark. [email protected]; Center for Sensory–Motor Interaction, Department of Health Sciences and Technology, Laboratory for Experimental Pain Research, Aalborg University, Fredrik Bajers Vej 7 D3, DK-9220, Aalborg, Denmark. [email protected]
&
Hans Christian Hoeck C4Pain and CCBR, Hobrovej 42, DK-9000 Aalborg, Denmark; C4Pain and CCBR, Hobrovej 42, DK-9000 Aalborg, Denmark
Pages 1631-1651 | Published online: 09 Jan 2014

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Morten Sejer Hansen, Jørn Wetterslev, Christian Bressen Pipper, Mohammad Sohail Asghar & Jørgen Berg Dahl. (2017) Heat pain detection threshold is associated with the area of secondary hyperalgesia following brief thermal sensitization: a study of healthy male volunteers. Journal of Pain Research 10, pages 265-274.
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Lars Arendt-Nielsen, Thomas Arendt Nielsen & Parisa Gazerani. (2014) Translational pain biomarkers in the early development of new neurotherapeutics for pain management. Expert Review of Neurotherapeutics 14:3, pages 241-254.
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Articles from other publishers (11)

Xiaohan Xu & Yuguang Huang. (2020) Objective Pain Assessment: a Key for the Management of Chronic Pain. F1000Research 9, pages 35.
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Trevor Thompson, Devin B. Terhune, Charlotte Oram, Joseph Sharangparni, Rommana Rouf, Marco Solmi, Nicola Veronese & Brendon Stubbs. (2019) The effectiveness of hypnosis for pain relief: A systematic review and meta-analysis of 85 controlled experimental trials. Neuroscience & Biobehavioral Reviews 99, pages 298-310.
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A. Taneja, O. Della Pasqua & M. Danhof. (2017) Challenges in translational drug research in neuropathic and inflammatory pain: the prerequisites for a new paradigm. European Journal of Clinical Pharmacology 73:10, pages 1219-1236.
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Lars Arendt-Nielsen, Steve Harris, Garth T. Whiteside, Michele Hummel, Terri Knappenberger, Sarah O'Keefe, Ram Kapil & Don Kyle. (2016) A randomized, double-blind, positive-controlled, 3-way cross-over human experimental pain study of a TRPV1 antagonist (V116517) in healthy volunteers and comparison with preclinical profile. Pain 157:9, pages 2057-2067.
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Siro Luvisetto, Parisa Gazerani, Carlo Cianchetti & Flaminia Pavone. (2015) Botulinum Toxin Type A as a Therapeutic Agent against Headache and Related Disorders. Toxins 7:9, pages 3818-3844.
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Lars Arendt-Nielsen. 2015. Pain Control. Pain Control 79 102 .
Ann G Hayes, Lars Arendt-Nielsen & Simon Tate. (2014) Multiple mechanisms have been tested in pain—how can we improve the chances of success?. Current Opinion in Pharmacology 14, pages 11-17.
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Lars Arendt-Nielsen & Michele Curatolo. (2013) Mechanistic, translational, quantitative pain assessment tools in profiling of pain patients and for development of new analgesic compounds. Scandinavian Journal of Pain 4:4, pages 226-230.
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K. Grosen, I.W.D. Fischer, A.E. Olesen & A.M. Drewes. (2013) Can quantitative sensory testing predict responses to analgesic treatment?. European Journal of Pain 17:9, pages 1267-1280.
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Mellar P. Davis & Geoffrey Mitchell. (2012) Reconstructing analgesic trials. Current Opinion in Supportive & Palliative Care 6:4, pages 490-493.
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. (2012) Current World Literature. Current Opinion in Anaesthesiology 25:5, pages 629-638.
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