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Editorial

Glutamate hypothesis of depression and its consequences for antidepressant treatments

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Pages 1169-1172 | Published online: 09 Jan 2014

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Dhaval Patel, Prashant S. Kharkar & Mukesh Nandave. (2015) Emerging roles of system antiporter and its inhibition in CNS disorders. Molecular Membrane Biology 32:4, pages 89-116.
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Agnieszka Pałucha-Poniewiera, Bartosz Bobula & Anna Rafało-Ulińska. (2023) The Antidepressant-like Activity and Cognitive Enhancing Effects of the Combined Administration of (R)-Ketamine and LY341495 in the CUMS Model of Depression in Mice Are Related to the Modulation of Excitatory Synaptic Transmission and LTP in the PFC. Pharmaceuticals 16:2, pages 288.
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Scott A. Kinlein, Naomi K. Wallace, Marina I. Savenkova & Ilia N. Karatsoreos. (2022) Chronic hypothalamic-pituitary-adrenal axis disruption alters glutamate homeostasis and neural responses to stress in male C57Bl6/N mice. Neurobiology of Stress 19, pages 100466.
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Ilya Demchenko, Vanessa K. Tassone, Sidney H. Kennedy, Katharine Dunlop & Venkat Bhat. (2022) Intrinsic Connectivity Networks of Glutamate-Mediated Antidepressant Response: A Neuroimaging Review. Frontiers in Psychiatry 13.
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Benjamin Fredrick Gruenbaum, Alexander Zlotnik, Amit Frenkel, Ilya Fleidervish & Matthew Boyko. (2022) Glutamate Efflux across the Blood–Brain Barrier: New Perspectives on the Relationship between Depression and the Glutamatergic System. Metabolites 12:5, pages 459.
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Xenia Gonda, Peter Dome, Joanna C. Neill & Frank I. Tarazi. (2021) Novel antidepressant drugs: Beyond monoamine targets. CNS Spectrums, pages 1-10.
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Deborah Chiabrando, Veronica Fiorito, Sara Petrillo, Francesca Bertino & Emanuela Tolosano. (2021) HEME: a neglected player in nociception?. Neuroscience & Biobehavioral Reviews 124, pages 124-136.
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Samuel J. Millard, Katrina Weston-Green & Kelly A. Newell. (2020) The Wistar-Kyoto rat model of endogenous depression: A tool for exploring treatment resistance with an urgent need to focus on sex differences. Progress in Neuro-Psychopharmacology and Biological Psychiatry 101, pages 109908.
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Omar K. Sial, Eric M. Parise, Lyonna F. Parise, Tamara Gnecco & Carlos A. Bolaños-Guzmán. (2020) Ketamine: The final frontier or another depressing end?. Behavioural Brain Research 383, pages 112508.
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Maryam Ardalan, Betina Elfving, Ali H. Rafati, Monireh Mansouri, Carlos A. ZarateJrJr, Aleksander A. Mathe & Gregers Wegener. (2020) Rapid effects of S-ketamine on the morphology of hippocampal astrocytes and BDNF serum levels in a sex-dependent manner. European Neuropsychopharmacology 32, pages 94-103.
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Scott A. Kinlein & Ilia N. Karatsoreos. (2020) The hypothalamic-pituitary-adrenal axis as a substrate for stress resilience: Interactions with the circadian clock. Frontiers in Neuroendocrinology 56, pages 100819.
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Bernhard Luscher, Mengyang Feng & Sarah J. Jefferson. 2020. Rapid Acting Antidepressants. Rapid Acting Antidepressants 43 78 .
Ariandra G. Sartim, Bianca M. Brito, Pedro H. Gobira & Sâmia R.L. Joca. (2019) Attenuation of glutamatergic and nitrergic system contributes to the antidepressant-like effect induced by capsazepine in the forced swimming test. Behavioural Pharmacology 30:1, pages 59-66.
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Boldizsár Czéh, Irina Vardya, Zsófia Varga, Fabia Febbraro, Dávid Csabai, Lena-Sophie Martis, Kristoffer Højgaard, Kim Henningsen, Elena V. Bouzinova, Attila Miseta, Kimmo Jensen & Ove Wiborg. (2018) Long-Term Stress Disrupts the Structural and Functional Integrity of GABAergic Neuronal Networks in the Medial Prefrontal Cortex of Rats. Frontiers in Cellular Neuroscience 12.
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Min Zhou, Maohua Wang, Xiaobin Wang, Kezhi Liu, YunQiang Wan, Mao Li, Li Liu & Chunxiang Zhang. (2017) Abnormal Expression of MicroRNAs Induced by Chronic Unpredictable Mild Stress in Rat Hippocampal Tissues. Molecular Neurobiology 55:2, pages 917-935.
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Lei-Yu Geng, Fang-Yuan Qian, Jun-Feng Qian & Zhi-Jun Zhang. (2017) The combination of plasma glutamate and physical impairment after acute stroke as a potential indicator for the early-onset post-stroke depression. Journal of Psychosomatic Research 96, pages 35-41.
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Xiaoliu Zhang, Yingying Tang, Mirjana Maletic-Savatic, Jianhua Sheng, Xuanhong Zhang, Yajing Zhu, Tianhong Zhang, Junjie Wang, Shanbao Tong, Jijun Wang & Yao Li. (2016) Altered neuronal spontaneous activity correlates with glutamate concentration in medial prefrontal cortex of major depressed females: An fMRI-MRS study. Journal of Affective Disorders 201, pages 153-161.
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Cassiano R.A.F. Diniz, Plínio C. Casarotto & Sâmia R.L. Joca. (2016) NMDA-NO signaling in the dorsal and ventral hippocampus time-dependently modulates the behavioral responses to forced swimming stress. Behavioural Brain Research 307, pages 126-136.
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