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Drug Profile

Roflumilast for the treatment of chronic obstructive pulmonary disease

Pages 543-555 | Published online: 09 Jan 2014

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Henrik Watz, Nitin Bagul, Klaus F Rabe, Stephen Rennard, Vijay KT Alagappan, Jonas Román, Axel Facius & Peter MA Calverley. (2018) Use of a 4-week up-titration regimen of roflumilast in patients with severe COPD. International Journal of Chronic Obstructive Pulmonary Disease 13, pages 813-822.
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Wim Vos, Bita Hajian, Jan De Backer, Cedric Van Holsbeke, Samir Vinchurkar, Rita Claes, Annemie Hufkens, Paul M Parizel, Lieven Bedert & Wilfried De Backer. (2016) Functional respiratory imaging to assess the interaction between systemic roflumilast and inhaled ICS/LABA/LAMA. International Journal of Chronic Obstructive Pulmonary Disease 11, pages 263-271.
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Articles from other publishers (16)

Jae-Hong Min, Min-Gu Kim, Seong-Man Kim, Ji-Won Park, Wanjoo Chun, Hee Jae Lee, Sei-Ryang Oh, Kyung-Seop Ahn & Jae-Won Lee. (2020) 3,4,5-Trihydroxycinnamic acid exerts a protective effect on pulmonary inflammation in an experimental animal model of COPD. International Immunopharmacology 85, pages 106656.
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Stefan Hadzic, Cheng-Yu Wu, Sergey Avdeev, Norbert Weissmann, Ralph Theo Schermuly & Djuro Kosanovic. (2020) Lung epithelium damage in COPD – An unstoppable pathological event?. Cellular Signalling 68, pages 109540.
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Roy Pleasants. 2020. Cardiac Considerations in Chronic Lung Disease. Cardiac Considerations in Chronic Lung Disease 161 212 .
Екатерина Кулик, Ekaterina Kulik, Валентина Павленко, Valentina Pavlenko, Светлана Нарышкина & Svetlana Naryshkina. (2019) PREDICTING THE EFFECTIVENESS OF TREATMENT WITH ROFLUMILAST IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE. Bulletin physiology and pathology of respiration 1:71, pages 51-56.
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P. KOSUTOVA, P. MIKOLKA, M. KOLOMAZNIK, S. REZAKOVA, A. CALKOVSKA & D. MOKRA. (2017) Effects of Roflumilast, a Phosphodiesterase-4 Inhibitor, on the Lung Functions in a Saline Lavage-Induced Model of Acute Lung Injury. Physiological Research, pages S237-S245.
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Ezigbobiara N. Umejiego, Yanhua Wang, Mark A. Knepper & Chung-Lin Chou. (2017) Roflumilast and aquaporin-2 regulation in rat renal inner medullary collecting duct. Physiological Reports 5:2, pages e13121.
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Prescott G Woodruff, Alvar Agusti, Nicolas Roche, Dave Singh & Fernando J Martinez. (2015) Current concepts in targeting chronic obstructive pulmonary disease pharmacotherapy: making progress towards personalised management. The Lancet 385:9979, pages 1789-1798.
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Katharine H. Abbott-Banner & Clive P. Page. (2014) Dual PDE3/4 and PDE4 Inhibitors: Novel Treatments For COPD and Other Inflammatory Airway Diseases. Basic & Clinical Pharmacology & Toxicology 114:5, pages 365-376.
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Clive P. Page. (2014) Phosphodiesterase Inhibitors for the Treatment of Asthma and Chronic Obstructive Pulmonary Disease. International Archives of Allergy and Immunology 165:3, pages 152-164.
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Vladimir Koblizek, Jan Chlumsky, Vladimir Zindr, Katerina Neumannova, Jakub Zatloukal, Jaroslav Zak, Vratislav Sedlak, Jana Kocianova, Jaromir Zatloukal, Karel Hejduk & Sarka Pracharova. (2013) Chronic Obstructive Pulmonary Disease: Official diagnosis and treatment guidelines of the Czech Pneumological and Phthisiological Society; a novel phenotypic approach to COPD with patient-oriented care. Biomedical Papers 157:2, pages 189-201.
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A. Arnedillo Muñoz. (2012) Consenso sobre atención integral de las agudizaciones de la enfermedad pulmonar obstructiva crónica (ATINA-EPOC). Parte II. SEMERGEN - Medicina de Familia 38:6, pages 394-399.
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Maisha L. Kelly Freeman. (2012) Clinical Considerations for Roflumilast: A New Treatment for COPD. The Consultant Pharmacist 27:3, pages 189-193.
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Kevin K.-C. Liu, Subas M. Sakya, Christopher J. O’Donnell, Andrew C. Flick & Hong X. Ding. (2012) Synthetic approaches to the 2010 new drugs. Bioorganic & Medicinal Chemistry 20:3, pages 1155-1174.
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Klaus F. Rabe. 2012. Clinical Respiratory Medicine. Clinical Respiratory Medicine 213 220 .
Andrew Churg, Don D. Sin & Joanne L. Wright. (2011) Everything Prevents Emphysema. American Journal of Respiratory Cell and Molecular Biology 45:6, pages 1111-1115.
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P. Devillier, G. Jebrak, H. Morel, T. Chinet, A. Didier & N. Roche. (2011) Prise en charge thérapeutique de l’atteinte des voies aériennes distales dans la BPCO. Revue des Maladies Respiratoires 28:10, pages 1340-1356.
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