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Review

An update on vaccine therapy and other immunotherapeutic approaches for glioblastoma

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Pages 597-615 | Published online: 09 Jan 2014

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (5)

S. Harrison Farber, Aladine A. Elsamadicy, Ahmet Fatih Atik, Carter M. Suryadevara, Pakawat Chongsathidkiet, Peter E. Fecci & John H. Sampson. (2017) The Safety of available immunotherapy for the treatment of glioblastoma. Expert Opinion on Drug Safety 16:3, pages 277-287.
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Yi Lin & Hideho Okada. (2016) Cellular immunotherapy for malignant gliomas. Expert Opinion on Biological Therapy 16:10, pages 1265-1275.
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Neha Kamran, Alexandra Calinescu, Marianela Candolfi, Mayuri Chandran, Yohei Mineharu, Antonela S. Asad, Carl Koschmann, Felipe J. Nunez, Pedro R. Lowenstein & Maria G. Castro. (2016) Recent advances and future of immunotherapy for glioblastoma. Expert Opinion on Biological Therapy 16:10, pages 1245-1264.
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Pedro R Lowenstein, Gregory J Baker & Maria G Castro. (2014) Cracking the glioma-NK inhibitory code: toward successful innate immunotherapy. OncoImmunology 3:11.
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Articles from other publishers (44)

Kelly M Hotchkiss, Kristen A Batich, Aditya Mohan, Rifaquat Rahman, Steven Piantadosi & Mustafa Khasraw. (2023) Dendritic cell vaccine trials in gliomas: Untangling the lines. Neuro-Oncology.
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Wenhua He, Qingxuan Li, Yan Lu, Dingyue Ju, Yu Gu, Kai Zhao & Chuanming Dong. (2022) Cancer Treatment Evolution from Traditional Methods to Stem Cells and Gene Therapy. Current Gene Therapy 22:5, pages 368-385.
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Landon J. Hansen, Rui Yang, Kristen Roso, Wenzhe Wang, Lee Chen, Qing Yang, Christopher J. Pirozzi & Yiping He. (2022) MTAP loss correlates with an immunosuppressive profile in GBM and its substrate MTA stimulates alternative macrophage polarization. Scientific Reports 12:1.
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Michael Kilian, Theresa Bunse, Wolfgang Wick, Michael Platten & Lukas Bunse. (2021) Genetically Modified Cellular Therapies for Malignant Gliomas. International Journal of Molecular Sciences 22:23, pages 12810.
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Stanley S. Stylli. (2020) Novel Treatment Strategies for Glioblastoma. Cancers 12:10, pages 2883.
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Elizabeth A. Maher & Robert M. Bachoo. 2020. Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease. Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease 173 182 .
Mahsa Keshavarz-Fathi & Nima Rezaei. 2019. Vaccines for Cancer Immunotherapy. Vaccines for Cancer Immunotherapy 45 59 .
Christina Karavasili, Emmanuel Panteris, Ioannis S. Vizirianakis, Sotirios Koutsopoulos & Dimitrios G. Fatouros. (2018) Chemotherapeutic Delivery from a Self-Assembling Peptide Nanofiber Hydrogel for the Management of Glioblastoma. Pharmaceutical Research 35:8.
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Pedro R. Lowenstein & Maria G. Castro. (2018) Evolutionary basis of a new gene- and immune-therapeutic approach for the treatment of malignant brain tumors: from mice to clinical trials for glioma patients. Clinical Immunology 189, pages 43-51.
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Neha Kamran, Mahmoud S Alghamri, Felipe J Nunez, Diana Shah, Antonela S Asad, Marianela Candolfi, David Altshuler, Pedro R Lowenstein & Maria G Castro. (2018) Current state and future prospects of immunotherapy for glioma. Immunotherapy 10:4, pages 317-339.
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Zinal S. Chheda, Gary Kohanbash, Kaori Okada, Naznin Jahan, John Sidney, Matteo Pecoraro, Xinbo Yang, Diego A. Carrera, Kira M. Downey, Shruti Shrivastav, Shuming Liu, Yi Lin, Chetana Lagisetti, Pavlina Chuntova, Payal B. Watchmaker, Sabine Mueller, Ian F. Pollack, Raja Rajalingam, Angel M. Carcaboso, Matthias Mann, Alessandro Sette, K. Christopher Garcia, Yafei Hou & Hideho Okada. (2018) Novel and shared neoantigen derived from histone 3 variant H3.3K27M mutation for glioma T cell therapy. Journal of Experimental Medicine 215:1, pages 141-157.
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Shabierjiang JIAPAER, Takuya FURUTA, Shingo TANAKA, Tomohiro KITABAYASHI & Mitsutoshi NAKADA. (2018) Potential Strategies Overcoming the Temozolomide Resistance for Glioblastoma. Neurologia medico-chirurgica 58:10, pages 405-421.
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Alain L Fymat. (2017) Cancer Therapy with Chimeric Antigen Receptors - A Landmark Moment for Cancer Immunotherapy. Journal of Cancer Prevention & Current Research 8:6.
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Emily K. Bongiorno, Samantha A. Garcia, Sami Sauma & D. Craig Hooper. (2017) Type 1 Immune Mechanisms Driven by the Response to Infection with Attenuated Rabies Virus Result in Changes in the Immune Bias of the Tumor Microenvironment and Necrosis of Mouse GL261 Brain Tumors. The Journal of Immunology 198:11, pages 4513-4523.
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David A. Reardon, Patrick Y. Wen, Kai W. Wucherpfennig & John H. Sampson. (2017) Immunomodulation for glioblastoma. Current Opinion in Neurology 30:3, pages 361-369.
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Gary Kohanbash, Diego A. Carrera, Shruti Shrivastav, Brian J. Ahn, Naznin Jahan, Tali Mazor, Zinal S. Chheda, Kira M. Downey, Payal B. Watchmaker, Casey Beppler, Rolf Warta, Nduka A. Amankulor, Christel Herold-Mende, Joseph F. Costello & Hideho Okada. (2017) Isocitrate dehydrogenase mutations suppress STAT1 and CD8+ T cell accumulation in gliomas. Journal of Clinical Investigation 127:4, pages 1425-1437.
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Wan-Lun Yan, Kuan-Yin Shen, Chun-Yuan Tien, Yu-An Chen & Shih-Jen Liu. (2017) Recent progress in GM-CSF-based cancer immunotherapy. Immunotherapy 9:4, pages 347-360.
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Tanner M. Johanns & Gavin P. Dunn. (2017) Applied Cancer Immunogenomics. The Cancer Journal 23:2, pages 125-130.
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Soumen Saha, Yakati Venu, Dwaipayan Bhattacharya, Shobha Deepthi Kompella, Kuncha Madhusudana, Sumana Chakravarty, Sistla Ramakrishna & Arabinda Chaudhuri. (2017) Combating Established Mouse Glioblastoma through Nicotinylated-Liposomes-Mediated Targeted Chemotherapy in Combination with Dendritic-Cell-Based Genetic Immunization. Advanced Biosystems 1:1-2, pages 1600009.
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Eiichi ISHIKAWA, Tetsuya YAMAMOTO & Akira MATSUMURA. (2017) Prospect of Immunotherapy for Glioblastoma: Tumor Vaccine, Immune Checkpoint Inhibitors and Combination Therapy. Neurologia medico-chirurgica 57:7, pages 321-330.
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L. Sanchez-Perez, C.M. Suryadevara, B.D. Choi & L.A. Johnson. 2017. Translational Immunotherapy of Brain Tumors. Translational Immunotherapy of Brain Tumors 337 365 .
Anning LiYue WuFeng TangWei LiXiaoyuan FengZhenwei Yao. (2016) In Vivo Magnetic Resonance Imaging of CD8+ T Lymphocytes Recruiting to Glioblastoma in Mice . Cancer Biotherapy and Radiopharmaceuticals 31:9, pages 317-323.
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SHIJIE HU, BING LI, XUEFENG SHEN, RUI ZHANG, DAKUAN GAO, QINGDONG GUO, YAN JIN & ZHOU FEI. (2016) Induction of antigen-specific cytotoxic T-cell response by dendritic cells generated from ecto-mesenchymal stem cells infected with an adenovirus containing the MAGE-D4a gene. Oncology Letters 11:4, pages 2886-2892.
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Jeffrey Wojton, Walter Hans Meisen & Balveen Kaur. (2015) How to train glioma cells to die: molecular challenges in cell death. Journal of Neuro-Oncology 126:3, pages 377-384.
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Patrick Roth, Matthias Preusser & Michael Weller. (2016) Immunotherapy of Brain Cancer. Oncology Research and Treatment 39:6, pages 326-334.
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P.R. Lowenstein & M.G. Castro. 2016. Neuropsychopharmacology: A Tribute to Joseph T. Coyle. Neuropsychopharmacology: A Tribute to Joseph T. Coyle 147 173 .
Giovanna Lollo, Marie Vincent, Gabriela Ullio-Gamboa, Laurent Lemaire, Florence Franconi, Dominique Couez & Jean-Pierre Benoit. (2015) Development of multifunctional lipid nanocapsules for the co-delivery of paclitaxel and CpG-ODN in the treatment of glioblastoma.. International Journal of Pharmaceutics 495:2, pages 972-980.
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Martha R. Neagu & David A. Reardon. (2015) An Update on the Role of Immunotherapy and Vaccine Strategies for Primary Brain Tumors. Current Treatment Options in Oncology 16:11.
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Anda-Alexandra Calinescu, Neha Kamran, Gregory Baker, Yohei Mineharu, Pedro Ricardo Lowenstein & Maria Graciela Castro. (2015) Overview of current immunotherapeutic strategies for glioma. Immunotherapy 7:10, pages 1073-1104.
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Cornelis J.M. Melief, Thorbald van Hall, Ramon Arens, Ferry Ossendorp & Sjoerd H. van der Burg. (2015) Therapeutic cancer vaccines. Journal of Clinical Investigation 125:9, pages 3401-3412.
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Madiha Derouazi, Wilma Di Berardino-Besson, Elodie Belnoue, Sabine Hoepner, Romy Walther, Mahdia Benkhoucha, Patrick Teta, Yannick Dufour, Céline Yacoub Maroun, Andres M. Salazar, Denis Martinvalet, Pierre-Yves Dietrich & Paul R. Walker. (2015) Novel Cell-Penetrating Peptide-Based Vaccine Induces Robust CD4+ and CD8+ T Cell–Mediated Antitumor Immunity. Cancer Research 75:15, pages 3020-3031.
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David A. Reardon & Hideho Okada. (2015) Re-defining response and treatment effects for neuro-oncology immunotherapy clinical trials. Journal of Neuro-Oncology 123:3, pages 339-346.
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Howard A. Fine. (2015) New Strategies in Glioblastoma: Exploiting the New Biology. Clinical Cancer Research 21:9, pages 1984-1988.
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Susanne Grube, Tatjana Göttig, Diana Freitag, Christian Ewald, Rolf Kalff & Jan Walter. (2015) Selection of suitable reference genes for expression analysis in human glioma using RT-qPCR. Journal of Neuro-Oncology 123:1, pages 35-42.
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Liu Yang, Geng Guo, Xiao-yuan Niu & Jing Liu. (2015) Dendritic Cell-Based Immunotherapy Treatment for Glioblastoma Multiforme. BioMed Research International 2015, pages 1-12.
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Elizabeth A. Maher & Robert M. Bachoo. 2015. Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease. Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease 909 917 .
Derek A. Wainwright, Alan L. Chang, Mahua Dey, Irina V. Balyasnikova, Chung Kwon Kim, Alex Tobias, Yu Cheng, Julius W. Kim, Jian Qiao, Lingjiao Zhang, Yu Han & Maciej S. Lesniak. (2014) Durable Therapeutic Efficacy Utilizing Combinatorial Blockade against IDO, CTLA-4, and PD-L1 in Mice with Brain Tumors. Clinical Cancer Research 20:20, pages 5290-5301.
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Andrea Schuessler, David G. Walker & Rajiv Khanna. (2014) Cytomegalovirus as a Novel Target for Immunotherapy of Glioblastoma Multiforme. Frontiers in Oncology 4.
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M. Candolfi & Marianela Candolfi. (2014) Terapia génica citotóxica para el tratamiento del cáncer cerebral. Neurología Argentina 6:4, pages 217-224.
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Andrea Schuessler, Corey Smith, Leone Beagley, Glen M. Boyle, Sweera Rehan, Katherine Matthews, Linda Jones, Tania Crough, Vijayendra Dasari, Kerenaftali Klein, Amy Smalley, Hamish Alexander, David G. Walker & Rajiv Khanna. (2014) Autologous T-cell Therapy for Cytomegalovirus as a Consolidative Treatment for Recurrent Glioblastoma. Cancer Research 74:13, pages 3466-3476.
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Pierre-Yves DietrichValérie DutoitPaul R. Walker. (2014) Immunotherapy for Glioma: From Illusion to Realistic Prospects?. American Society of Clinical Oncology Educational Book:34, pages 51-59.
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