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Jong Hwan Sung. (2021) Multi-organ-on-a-chip for pharmacokinetics and toxicokinetic study of drugs. Expert Opinion on Drug Metabolism & Toxicology 17:8, pages 969-986.
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Articles from other publishers (71)
Luming Wang, Danping Hu, Jinming Xu, Jian Hu & Yifei Wang. (2024) Complex in vitro model: A transformative model in drug development and precision medicine. Clinical and Translational Science 17:2.
Crossref
Crossref
Thomas Däullary, Fabian Imdahl, Oliver Dietrich, Laura Hepp, Tobias Krammer, Christina Fey, Winfried Neuhaus, Marco Metzger, Jörg Vogel, Alexander J. Westermann, Antoine-Emmanuel Saliba & Daniela Zdzieblo. (2023) A primary cell-based in vitro model of the human small intestine reveals host olfactomedin 4 induction in response to Salmonella Typhimurium infection. Gut Microbes 15:1.
Crossref
Crossref
Burak Ozgür, Elena Puris, Andreas Brachner, Antje Appelt-Menzel, Sabrina Oerter, Viktor Balzer, Mikkel Roland Holst, Rasmus Folmann Christiansen, Kathrine Hyldig, Stephen T. Buckley, Mie Kristensen, Seppo Auriola, Allan Jensen, Gert Fricker, Morten Schallburg Nielsen, Winfried Neuhaus & Birger Brodin. (2023) Characterization of an iPSC-based barrier model for blood-brain barrier investigations using the SBAD0201 stem cell line. Fluids and Barriers of the CNS 20:1.
Crossref
Crossref
Gabriele Addario, Daphne Eussen, Sonja Djudjaj, Peter Boor, Lorenzo Moroni & Carlos Mota. (2023) 3D Printed Tubulointerstitium Chip as an In Vitro Testing Platform. Macromolecular Bioscience.
Crossref
Crossref
Lingyu Sun, Feika Bian, Dongyu Xu, Yuan Luo, Yongan Wang & Yuanjin Zhao. (2023) Tailoring biomaterials for biomimetic organs-on-chips. Materials Horizons 10:11, pages 4724-4745.
Crossref
Crossref
Yeongseok Jang, Jinmu Jung & Jonghyun Oh. (2023) Bio–Microfabrication of 2D and 3D Biomimetic Gut-on-a-Chip. Micromachines 14:9, pages 1736.
Crossref
Crossref
B. Atac Wagegg, L. Koenig, A. Ramme, U. Marx & E. Dehne. (2023) P16-23: Blood-Brain Barrier Permeation in the Autologous Stem Cell-Derived Four-Organ-Chip. Toxicology Letters 384, pages S194.
Crossref
Crossref
Nikita Narayan Naik, Bharadwaja Vadloori, Suresh Poosala, Pratima Srivastava, Sandra Coecke, Adrian Smith, Aysha Akhtar, Clive Roper, Sridhar Radhakrishnan, Balaji Bhyravbhatla, Madhujit Damle, Venkat Koushik Pulla, Johannes Hackethal, Reyk Horland, Albert P. Li, Falguni Pati, Manu Smriti Singh, Paola Occhetta, Rohit Bisht, Prajakta Dandekar, Krishna Bhagavatula, Dasja Pajkrt, Michael Johnson, Tilo Weber, John Huang, Lisiena Hysenaj, Banerjee Mallar, Bhat Ramray, Santosh Dixit, Shreekanth Joshi & Mandar Kulkarni. (2023) Advances in Animal Models and Cutting-Edge Research in Alternatives: Proceedings of the Third International Conference on 3Rs Research and Progress, Vishakhapatnam, 2022. Alternatives to Laboratory Animals 51:4, pages 263-288.
Crossref
Crossref
Allard W. J. van Renterghem, Joris van de Haar & Emile E. Voest. (2023) Functional precision oncology using patient-derived assays: bridging genotype and phenotype. Nature Reviews Clinical Oncology 20:5, pages 305-317.
Crossref
Crossref
Amin Valiei, Javad Aminian-Dehkordi & Mohammad R. K. Mofrad. (2023) Gut-on-a-chip models for dissecting the gut microbiology and physiology. APL Bioengineering 7:1.
Crossref
Crossref
Lei Wu, Yongjian Ai, Ruoxiao Xie, Jialiang Xiong, Yu Wang & Qionglin Liang. (2023) Organoids/organs-on-a-chip: new frontiers of intestinal pathophysiological models. Lab on a Chip 23:5, pages 1192-1212.
Crossref
Crossref
Kirsten Pondman, Séverine Le Gac & Uday Kishore. (2023) Nanoparticle-induced immune response: Health risk versus treatment opportunity?. Immunobiology 228:2, pages 152317.
Crossref
Crossref
Adriana Oliveira Manfiolli, Robson Amaral & Carolina Caliari-Oliveira. 2023. Nanotechnology and Regenerative Medicine. Nanotechnology and Regenerative Medicine
233
263
.
Duygu Uçkan-Çetinkaya & Khawaja Husnain Haider. 2023. Stammzellen. Stammzellen
225
240
.
Joachim Wiest. (2022) Systems engineering of microphysiometry. Organs-on-a-Chip 4, pages 100016.
Crossref
Crossref
Lisa Buvall, Robert I. Menzies, Julie Williams, Kevin J. Woollard, Chanchal Kumar, Anna B. Granqvist, Maria Fritsch, Denis Feliers, Anna Reznichenko, Davide Gianni, Slavé Petrovski, Claus Bendtsen, Mohammad Bohlooly-Y, Carolina Haefliger, Regina Fritsche Danielson & Pernille B. L. Hansen. (2022) Selecting the right therapeutic target for kidney disease. Frontiers in Pharmacology 13.
Crossref
Crossref
Sheeza Mughal, Gerardo A. López‐Muñoz, Juan M. Fernández‐Costa, Armando Cortés‐Reséndiz, Francesco De Chiara & Javier Ramón‐Azcón. (2022) Organs‐on‐Chips: Trends and Challenges in Advanced Systems Integration. Advanced Materials Interfaces 9:33.
Crossref
Crossref
Leopold Koenig, Anja Patricia Ramme, Daniel Faust, Manuela Mayer, Tobias Flötke, Anna Gerhartl, Andreas Brachner, Winfried Neuhaus, Antje Appelt-Menzel, Marco Metzger, Uwe Marx & Eva-Maria Dehne. (2022) A Human Stem Cell-Derived Brain-Liver Chip for Assessing Blood-Brain-Barrier Permeation of Pharmaceutical Drugs. Cells 11:20, pages 3295.
Crossref
Crossref
David Caballero, Rui L. Reis & Subhas C. Kundu. (2022) Boosting the Clinical Translation of Organ-on-a-Chip Technology. Bioengineering 9:10, pages 549.
Crossref
Crossref
Claire Duff & Julien Baruteau. (2022) Modelling urea cycle disorders using iPSCs. npj Regenerative Medicine 7:1.
Crossref
Crossref
Gülşah TORKAY & Ayça BAL ÖZTÜRK. (2022) A Stem Cell and Tissue Engineering Perspective on Microfluidic Chips. Journal of Polytechnic.
Crossref
Crossref
Donald E. Ingber. (2022) Human organs-on-chips for disease modelling, drug development and personalized medicine. Nature Reviews Genetics 23:8, pages 467-491.
Crossref
Crossref
Benoit Cox, Patrick Barton, Reiner Class, Hannah Coxhead, Claude Delatour, Eric Gillent, Jamie Henshall, Emre M. Isin, Lloyd King & Jean-Pierre Valentin. (2022) Setup of human liver-chips integrating 3D models, microwells and a standardized microfluidic platform as proof-of-concept study to support drug evaluation. Biomaterials and Biosystems 7, pages 100054.
Crossref
Crossref
Blanca Molins, Marina Mesquida & Alfredo Adan. (2022) WITHDRAWN: Bioengineering approaches for modelling retinal pathologies of the outer blood-retinal barrier. Progress in Retinal and Eye Research, pages 101097.
Crossref
Crossref
Pedro Caetano-Pinto & Janosch Schoon. (2022) The Applications of Microphysiological Systems in Biomedicine: Impact on Urologic and Orthopaedic Research. Encyclopedia 2:2, pages 1128-1137.
Crossref
Crossref
Sylvia E. Escher, Falko Partosch, Sebastian Konzok, Paul Jennings, Mirjam Luijten, Anne Kienhuis, Victoria de Leeuw, Rosmarie Reuss, Katrina‐Magdalena Lindemann & Susanne Hougaard Bennekou. (2022) Development of a Roadmap for Action on New Approach Methodologies in Risk Assessment. EFSA Supporting Publications 19:6.
Crossref
Crossref
Cleo Tebby, Wang Gao, Johannes Delp, Giada Carta, Wanda van der Stel, Marcel Leist, Paul Jennings, Bob van de Water & Frederic Y. Bois. (2022) A quantitative AOP of mitochondrial toxicity based on data from three cell lines. Toxicology in Vitro 81, pages 105345.
Crossref
Crossref
Leyla Amirifar, Amir Shamloo, Rohollah Nasiri, Natan Roberto de Barros, Ze Zhong Wang, Bige Deniz Unluturk, Alberto Libanori, Oleksandr Ievglevskyi, Sibel Emir Diltemiz, Samuel Sances, Ilangko Balasingham, Stephanie K. Seidlits & Nureddin Ashammakhi. (2022) Brain-on-a-chip: Recent advances in design and techniques for microfluidic models of the brain in health and disease. Biomaterials 285, pages 121531.
Crossref
Crossref
Jaeseo Lee, Seon Ju Mun, Yongbo Shin, Seonbhin Lee & Myung Jin Son. (2022) Advances in liver organoids: model systems for liver disease. Archives of Pharmacal Research 45:6, pages 390-400.
Crossref
Crossref
Chak Ming Leung, Pim de Haan, Kacey Ronaldson-Bouchard, Ge-Ah Kim, Jihoon Ko, Hoon Suk Rho, Zhu Chen, Pamela Habibovic, Noo Li Jeon, Shuichi Takayama, Michael L. Shuler, Gordana Vunjak-Novakovic, Olivier Frey, Elisabeth Verpoorte & Yi-Chin Toh. (2022) A guide to the organ-on-a-chip. Nature Reviews Methods Primers 2:1.
Crossref
Crossref
Mengyuan Wu, Tingting Hu, Ping Zhu, Moussa Ide Nasser, Jie Shen, Fang Sun, Qingnan He & Mingyi Zhao. (2022) Kidney organoids as a promising tool in nephrology. Genes & Diseases 9:3, pages 585-597.
Crossref
Crossref
Mathieu Danoy, Stéphane Poulain, Benedikt Scheidecker, Rachid Jellali, Yannick Tauran, Marjorie Leduc, Johanna Bruce, Francoise Gilard, Bertrand Gakiere, Hiroshi Arakawa, Yukio Kato, Soo Hyeon Kim, Taketomo Kido, Atsushi Miyajima, Yasuyuki Sakai & Eric Leclerc. (2022) Influence of CPM-dependent sorting on the multi-omics profile of hepatocyte-like cells matured in microscale biochips. Biochemical Engineering Journal 181, pages 108408.
Crossref
Crossref
Jennifer H. Hammel, Jonathan M. Zatorski, Sophie R. Cook, Rebecca R. Pompano & Jennifer M. Munson. (2022) Engineering in vitro immune-competent tissue models for testing and evaluation of therapeutics. Advanced Drug Delivery Reviews 182, pages 114111.
Crossref
Crossref
Katharina S. Nitsche, Iris Müller, Sophie Malcomber, Paul L. Carmichael & Hans Bouwmeester. (2022) Implementing organ-on-chip in a next-generation risk assessment of chemicals: a review. Archives of Toxicology 96:3, pages 711-741.
Crossref
Crossref
Martin Trapecar. (2021) Multiorgan microphysiological systems as tools to interrogate interorgan crosstalk and complex diseases. FEBS Letters 596:5, pages 681-695.
Crossref
Crossref
Francesca Fanizza, Marzia Campanile, Gianluigi Forloni, Carmen Giordano & Diego Albani. (2022) Induced pluripotent stem cell-based organ-on-a-chip as personalized drug screening tools: A focus on neurodegenerative disorders. Journal of Tissue Engineering 13, pages 204173142210953.
Crossref
Crossref
Kirk P. Van Ness, Francine Cesar, Catherine K. Yeung, Jonathan Himmelfarb & Edward J. Kelly. (2021) Microphysiological systems in absorption, distribution, metabolism, and elimination sciences. Clinical and Translational Science 15:1, pages 9-42.
Crossref
Crossref
Naheem Yaqub, Gareth Wayne, Martin Birchall & Wenhui Song. (2022) Recent advances in human respiratory epithelium models for drug discovery. Biotechnology Advances 54, pages 107832.
Crossref
Crossref
Nathan James Cunningham, Rahulkumar Bhoi & Huaxiao Yang. 2022. Current Topics in iPSCs Technology. Current Topics in iPSCs Technology
63
93
.
Viktoria Hentschel, Thomas Seufferlein & Milena Armacki. (2021) Intestinal organoids in coculture: redefining the boundaries of gut mucosa ex vivo modeling. American Journal of Physiology-Gastrointestinal and Liver Physiology 321:6, pages G693-G704.
Crossref
Crossref
Connor O'Farrell, Konstantinos Stamatopoulos, Mark Simmons & Hannah Batchelor. (2021) In vitro models to evaluate ingestible devices: Present status and current trends. Advanced Drug Delivery Reviews 178, pages 113924.
Crossref
Crossref
Letícia E. Charelli, João P. D. Ferreira, Carolina P. Naveira‐Cotta & Tiago A. Balbino. (2021) Engineering mechanobiology through organoids‐on‐chip: A strategy to boost therapeutics. Journal of Tissue Engineering and Regenerative Medicine 15:11, pages 883-899.
Crossref
Crossref
Rajkumar Singh Kalra, Jaspreet Kaur Dhanjal, Mriganko Das, Birbal Singh & Rajesh Naithani. (2021) Cell Transdifferentiation and Reprogramming in Disease Modeling: Insights into the Neuronal and Cardiac Disease Models and Current Translational Strategies. Cells 10:10, pages 2558.
Crossref
Crossref
Adrian Roth. (2021) Human microphysiological systems for drug development. Science 373:6561, pages 1304-1306.
Crossref
Crossref
Uwe Marx, Enrico Accastelli, Rhiannon David, Hendrik Erfurth, Leopold Koenig, Roland Lauster, Anja Patricia Ramme, Petra Reinke, Hans-Dieter Volk, Annika Winter & Eva-Maria Dehne. (2021) An Individual Patient's “Body” on Chips—How Organismoid Theory Can Translate Into Your Personal Precision Therapy Approach. Frontiers in Medicine 8.
Crossref
Crossref
Antonia Last, Michelle Maurer, Alexander S. Mosig, Mark S. Gresnigt & Bernhard Hube. (2021)
In vitro
infection models to study fungal–host interactions
. FEMS Microbiology Reviews 45:5.
Crossref
Crossref
Naomi ClappAugustin Amour, Wendy C. RowanPelin L. Candarlioglu. (2021) Organ-on-chip applications in drug discovery: an end user perspective. Biochemical Society Transactions 49:4, pages 1881-1890.
Crossref
Crossref
Laura Giordano, Silvia Maria Mihaila, Hossein Eslami Amirabadi & Rosalinde Masereeuw. (2021) Microphysiological Systems to Recapitulate the Gut–Kidney Axis. Trends in Biotechnology 39:8, pages 811-823.
Crossref
Crossref
Nathalie Picollet-D’hahan, Agnieszka Zuchowska, Iris Lemeunier & Séverine Le Gac. (2021) Multiorgan-on-a-Chip: A Systemic Approach To Model and Decipher Inter-Organ Communication. Trends in Biotechnology 39:8, pages 788-810.
Crossref
Crossref
Cristina Elena Staicu, Florin Jipa, Emanuel Axente, Mihai Radu, Beatrice Mihaela Radu & Felix Sima. (2021) Lab-on-a-Chip Platforms as Tools for Drug Screening in Neuropathologies Associated with Blood–Brain Barrier Alterations. Biomolecules 11:6, pages 916.
Crossref
Crossref
Amanda M Clark, Nancy L Allbritton & Alan Wells. (2021) Integrative microphysiological tissue systems of cancer metastasis to the liver. Seminars in Cancer Biology 71, pages 157-169.
Crossref
Crossref
Rachel E. Young & Dan Dongeun Huh. (2021) Organ-on-a-chip technology for the study of the female reproductive system. Advanced Drug Delivery Reviews 173, pages 461-478.
Crossref
Crossref
Fuyin Zheng, Yuminghao Xiao, Hui Liu, Yubo Fan & Ming Dao. (2021) Patient‐Specific Organoid and Organ‐on‐a‐Chip: 3D Cell‐Culture Meets 3D Printing and Numerical Simulation. Advanced Biology 5:6.
Crossref
Crossref
Anja Patricia Ramme, Daniel Faust, Leopold Koenig, Nhutuyen Nguyen & Uwe Marx. (2021) Generation of two additional integration-free iPSC lines from related human donors. Stem Cell Research 53, pages 102327.
Crossref
Crossref
Amy McTague, Giada Rossignoli, Arianna Ferrini, Serena Barral & Manju A. Kurian. (2021) Genome Editing in iPSC-Based Neural Systems: From Disease Models to Future Therapeutic Strategies. Frontiers in Genome Editing 3.
Crossref
Crossref
Wittaya Pimtong, Pawitrabhorn Samutrtai, Ratjika Wongwanakul & Sasitorn Aueviriyavit. 2021. Handbook of Nanotechnology Applications. Handbook of Nanotechnology Applications
683
710
.
Horst Spielmann & Helena Kandarova. 2020. Regulatory Toxicology. Regulatory Toxicology
1
14
.
Duygu Uçkan-Çetinkaya & Khawaja Husnain Haider. 2021. Stem Cells. Stem Cells
203
216
.
Horst Spielmann & Helena Kandarova. 2021. Regulatory Toxicology. Regulatory Toxicology
149
161
.
Clare L. Thompson, Su Fu, Hannah K. Heywood, Martin M. Knight & Stephen D. Thorpe. (2020) Mechanical Stimulation: A Crucial Element of Organ-on-Chip Models. Frontiers in Bioengineering and Biotechnology 8.
Crossref
Crossref
Anna Gerhartl, Nadja Pracser, Alexandra Vladetic, Sabrina Hendrikx, Heinz-Peter Friedl & Winfried Neuhaus. (2020) The pivotal role of micro-environmental cells in a human blood–brain barrier in vitro model of cerebral ischemia: functional and transcriptomic analysis. Fluids and Barriers of the CNS 17:1.
Crossref
Crossref
Polyxeni Nikolakopoulou, Rossana Rauti, Dimitrios Voulgaris, Iftach Shlomy, Ben M Maoz & Anna Herland. (2020)
Recent progress in translational engineered
in vitro
models of the central nervous system
. Brain 143:11, pages 3181-3213.
Crossref
Crossref
Huaqi Tang, Yasmine Abouleila, Longlong Si, Ana Maria Ortega-Prieto, Christine L. Mummery, Donald E. Ingber & Alireza Mashaghi. (2020) Human Organs-on-Chips for Virology. Trends in Microbiology 28:11, pages 934-946.
Crossref
Crossref
Eva-Maria Dehne & Uwe Marx. (2020) The universal physiological template—a system to advance medicines. Current Opinion in Toxicology 23-24, pages 1-5.
Crossref
Crossref
M. J. Moné, G. Pallocca, S. E. Escher, T. Exner, M. Herzler, S. Hougaard Bennekou, H. Kamp, E. D. Kroese, Marcel Leist, T. Steger-Hartmann & B. van de Water. (2020) Setting the stage for next-generation risk assessment with non-animal approaches: the EU-ToxRisk project experience. Archives of Toxicology 94:10, pages 3581-3592.
Crossref
Crossref
Ji‐Woo Kim, Ilkyun Im, Hyemin Kim, Jang Su Jeon, Eun‐Hye Kang, Seongyea Jo, Hang‐Suk Chun, Seokjoo Yoon, Jong‐Hoon Kim, Sang Kyum Kim & Han‐Jin Park. (2020) Live‐cell screening platform using human‐induced pluripotent stem cells expressing fluorescence‐tagged cytochrome P450 1A1. The FASEB Journal 34:7, pages 9141-9155.
Crossref
Crossref
Lauren Richardson, Sungjin Kim, Ramkumar Menon & Arum Han. (2020) Organ-On-Chip Technology: The Future of Feto-Maternal Interface Research?. Frontiers in Physiology 11.
Crossref
Crossref
Anna Julie Peired, Benedetta Mazzinghi, Letizia De Chiara, Francesco Guzzi, Laura Lasagni, Paola Romagnani & Elena Lazzeri. (2020) Bioengineering strategies for nephrologists: kidney was not built in a day. Expert Opinion on Biological Therapy 20:5, pages 467-480.
Crossref
Crossref
Arun Sharma, Samuel Sances, Michael J. Workman & Clive N. Svendsen. (2020) Multi-lineage Human iPSC-Derived Platforms for Disease Modeling and Drug Discovery. Cell Stem Cell 26:3, pages 309-329.
Crossref
Crossref
Ilka Maschmeyer & Sofia Kakava. 2022. Microfluidics in Biotechnology. Microfluidics in Biotechnology
311
342
.
Anja Patricia Ramme, Daniel Faust, Leopold Koenig & Uwe Marx. (2019) Generation of four integration-free iPSC lines from related human donors. Stem Cell Research 41, pages 101615.
Crossref
Crossref