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Breast Cancer: Targets and Therapy Volume 9, 2017 - Issue

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Original Research

Cholesterol biosynthesis inhibitor RO 48-8071 reduces progesterone receptor expression and inhibits progestin-dependent stem cell-like cell growth in hormone-dependent human breast cancer cells

Yayun Liang1 Department of Biomedical Sciences;2 Dalton Cardiovascular Research Center, University of Missouri, Columbia, MO, USA

Sandy Goyette1 Department of Biomedical Sciences;2 Dalton Cardiovascular Research Center, University of Missouri, Columbia, MO, USA

Salman M Hyder1 Department of Biomedical Sciences;2 Dalton Cardiovascular Research Center, University of Missouri, Columbia, MO, USACorrespondence[email protected]

Pages 487-494 | Published online: 07 Jul 2017

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Articles from other publishers (3)

Slight SH & Hyder SM. (2022) Should oxidosqualene cyclase in the cholesterol biosynthetic pathway be considered an anti-cancer target?. Frontiers in Cell and Developmental Biology 10.
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Babita Madan, David M. Virshup, W. David Nes & David J. Leaver. (2022) Unearthing the Janus-face cholesterogenesis pathways in cancer. Biochemical Pharmacology 196, pages 114611.
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Etienne Ho Kit Mok & Terence Kin Wah Lee. (2020) The Pivotal Role of the Dysregulation of Cholesterol Homeostasis in Cancer: Implications for Therapeutic Targets. Cancers 12:6, pages 1410.
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