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Breast Cancer: Targets and Therapy Volume 10, 2018 - Issue
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Original Research

A combination of p53-activating APR-246 and phosphatidylserine-targeting antibody potently inhibits tumor development in hormone-dependent mutant p53-expressing breast cancer xenografts

Yayun Liang1 Deparment of Biomedical Sciences and Dalton Cardiovascular Research Center, Columbia, MO, USA
,
Benford Mafuvadze1 Deparment of Biomedical Sciences and Dalton Cardiovascular Research Center, Columbia, MO, USA
,
Cynthia Besch-Williford2 IDEXX BioResearch, Columbia, MO, USA
&
Salman M Hyder1 Deparment of Biomedical Sciences and Dalton Cardiovascular Research Center, Columbia, MO, USACorrespondence[email protected]
Pages 53-67 | Published online: 22 Mar 2018

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Taylor P Berke, Simon H Slight & Salman M Hyder. (2022) Role of Reactivating Mutant p53 Protein in Suppressing Growth and Metastasis of Triple-Negative Breast Cancer. OncoTargets and Therapy 15, pages 23-30.
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Yayun Liang, Cynthia Besch-Williford, Matthew T Cook, Anthony Belenchia, Rolf A Brekken & Salman M Hyder. (2019) APR-246 alone and in combination with a phosphatidylserine-targeting antibody inhibits lung metastasis of human triple-negative breast cancer cells in nude mice. Breast Cancer: Targets and Therapy 11, pages 249-259.
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Articles from other publishers (2)

Ashwini Makhale, Devathri Nanayakkara, Prahlad Raninga, Kum Kum Khanna & Murugan Kalimutho. (2021) CX-5461 Enhances the Efficacy of APR-246 via Induction of DNA Damage and Replication Stress in Triple-Negative Breast Cancer. International Journal of Molecular Sciences 22:11, pages 5782.
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Elizabeth A. Lopes, Sara Gomes, Lucília Saraiva & Maria M.M. Santos. (2020) Small Molecules Targeting Mutant P53: A Promising Approach for Cancer Treatment. Current Medicinal Chemistry 26:41, pages 7323-7336.
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