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Breast Cancer: Targets and Therapy Volume 13, 2021 - Issue
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Original Research

Potentiating the Cytotoxic Activity of a Novel Simvastatin-Loaded Cubosome against Breast Cancer Cells: Insights on Dual Cell Death via Ferroptosis and Apoptosis

Yara E Elakkad1 Department of Pharmaceutics, College of Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science and Technology, Giza, Egypt
,
Shimaa Nabil Senousy Mohamed2 Biochemistry Division, Chemistry Department, Center of Basic Sciences, Misr University for Science and Technology, Giza, Egypt
&
Nermeen Z Abuelezz3 Biochemistry Department, College of Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science and Technology, Giza, EgyptCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-7775-2281
ORCID Icon
Pages 675-689 | Published online: 14 Dec 2021

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Priya Singh, Priyanka Maurya, Raquibun Nisha, Neelu Singh, Poonam Parashar, Nidhi Mishra, Ravi Raj Pal & Shubhini A. Saraf. (2023) QbD-assisted development of lipidic nanocapsules for antiestrogenic activity of exemestane in breast cancer. Journal of Liposome Research 33:2, pages 154-169.
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Articles from other publishers (6)

Popat KUMBHAR, Vıshvajıt KHADE, Varsha KHADAKE, Pradnya MARALE, Arehallı MANJAPPA, Sameer NADAF, Vıjay KUMBAR, Durgacharan BHAGWAT & John DİSOUZA. (2022) Ifosfamide-Loaded Cubosomes: An Approach to Potentiate Cytotoxicity against MDA-MB-231 Breast Cancer Cells. Fabad Journal of Pharmaceutical Sciences.
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Aleksandra Bartkowiak, Ewa Nazaruk, Ewa Gajda, Marlena Godlewska, Damian Gaweł, Elżbieta Jabłonowska & Renata Bilewicz. (2022) Simvastatin Coadministration Modulates the Electrostatically Driven Incorporation of Doxorubicin into Model Lipid and Cell Membranes. ACS Biomaterials Science & Engineering 8:10, pages 4354-4364.
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Krisztián Csomó, Andrea Belik, András Hrabák, Benedek Kovács, Orsolya Fábián, Sándor Valent, Gábor Varga & Zoltán Kukor. (2022) Effect of Pravastatin and Simvastatin on the Reduction of Cytochrome C. Journal of Personalized Medicine 12:7, pages 1121.
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Jiawei Feng, Jialin Wang, Yuqing Wang, Xiaoting Huang, Tengteng Shao, Xiaofei Deng, Yemin Cao, Mingmei Zhou & Cheng Zhao. (2022) Oxidative Stress and Lipid Peroxidation: Prospective Associations Between Ferroptosis and Delayed Wound Healing in Diabetic Ulcers. Frontiers in Cell and Developmental Biology 10.
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Mohammed A.S. Abourehab, Mohammad Javed Ansari, Anshul Singh, Ahmed Hassan, Mohamed A. Abdelgawad, Prachi Shrivastav, Bassam M. Abualsoud, Larissa Souza Amaral & Sheersha Pramanik. (2022) Cubosomes as an emerging platform for drug delivery: a review of the state of the art. Journal of Materials Chemistry B 10:15, pages 2781-2819.
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Chen Huang & Lei Zhan. (2022) Network Pharmacology Identifies Therapeutic Targets and the Mechanisms of Glutathione Action in Ferroptosis Occurring in Oral Cancer. Frontiers in Pharmacology 13.
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