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Blood and Lymphatic Cancer: Targets and Therapy Volume 2, 2012 - Issue
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Review

Role of L-asparaginase in acute lymphoblastic leukemia: focus on adult patients

Michael E RyttingDepartment of Pediatrics and Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX,USACorrespondence[email protected]
Pages 117-124 | Published online: 29 Jun 2012

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André Moreni Lopes, Laura de Oliveira-Nascimento, Artur Ribeiro, Carlos Abrunhosa Tairum$suffix/text()$suffix/text(), Carlos Alexandre Breyer, Marcos Antonio de Oliveira, Gisele Monteiro, Cristina Maria de Souza-Motta, Pérola de Oliveira Magalhães, Jorge Gonzalo Farías Avendaño, Artur Manuel Cavaco-Paulo, Priscila Gava Mazzola, Carlota de Oliveira Rangel-Yagui, Lara Durães Sette, Attilio Converti & Adalberto Pessoa. (2017) Therapeutic l-asparaginase: upstream, downstream and beyond. Critical Reviews in Biotechnology 37:1, pages 82-99.
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Leslie Sánchez, Fabiola E. Medina, Fernanda Mendoza, Camilo Febres-Molina & Gonzalo A. Jaña. (2022) Elucidation of the Reaction Mechanism of Cavia porcellus l -Asparaginase: A QM/MM Study . Journal of Chemical Information and Modeling 63:1, pages 270-280.
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Rajashekar Sindhu & Haravey K. Manonmani. (2022) L-asparaginase-mediated Therapy in L-asparagine Auxotrophic Cancers: A Review. Anti-Cancer Agents in Medicinal Chemistry 22:13, pages 2393-2410.
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Adriana Krupa, Johan de Vos, Lynn Van Eetvelde & Erik Teske. (2022) Pegylated asparaginase in feline high-grade lymphoma: clinical results of single injection and continued incorporation into a modified COP regimen. Journal of Feline Medicine and Surgery 24:8, pages e203-e213.
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Evgeniy Protasov, Larisa Koleva, Elizaveta Bovt, Fazoil I. Ataullakhanov & Elena Sinauridze. (2021) Theoretical Analysis of the Built-in Metabolic Pathway Effect on the Metabolism of Erythrocyte-Bioreactors That Neutralize Ammonium. Metabolites 11:1, pages 36.
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Chityala Sushma, Ashish Prabhu Anand & Venkata Dasu Veeranki. (2017) Enhanced production of glutaminase free L-asparaginase II by Bacillus subtilis WB800N through media optimization. Korean Journal of Chemical Engineering 34:11, pages 2901-2915.
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Christos S. Karamitros & Manfred Konrad. (2016) Fluorescence-Activated Cell Sorting of Human l -asparaginase Mutant Libraries for Detecting Enzyme Variants with Enhanced Activity . ACS Chemical Biology 11:9, pages 2596-2607.
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Lindsey Phillipson-WeinerEmily T. MirekYongping WangW. Geoffrey McAuliffe, Ronald C. Wek & Tracy G. Anthony. (2016) General control nonderepressible 2 deletion predisposes to asparaginase-associated pancreatitis in mice. American Journal of Physiology-Gastrointestinal and Liver Physiology 310:11, pages G1061-G1070.
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Usman Ali, Muhammad Naveed, Abid Ullah, Khadija Ali, Sayed Afzal Shah, Shah Fahad & Abdul Samad Mumtaz. (2016) L-asparaginase as a critical component to combat Acute Lymphoblastic Leukaemia (ALL): A novel approach to target ALL. European Journal of Pharmacology 771, pages 199-210.
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Viswanathan A. Nagaraj, Dhanunjay Mukhi, Vinayagam Sathishkumar, Pradeep A. Subramani, Susanta K. Ghosh, Rajeev R. Pandey, Manjunatha C. Shetty & Govindarajan Padmanaban. (2015) Asparagine requirement in Plasmodium berghei as a target to prevent malaria transmission and liver infections. Nature Communications 6:1.
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Sushma Chityala, Veeranki Venkata Dasu, Jamal Ahmad & Reddy Shetty Prakasham. (2015) High yield expression of novel glutaminase free l-asparaginase II of Pectobacterium carotovorum MTCC 1428 in Bacillus subtilis WB800N. Bioprocess and Biosystems Engineering 38:11, pages 2271-2284.
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Usman Ali. (2015) Seeking efficacy in L-asparaginase to combat acute lymphoblastic leukemia (ALL): A review. African Journal of Pharmacy and Pharmacology 9:32, pages 793-805.
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Brian A. Baldo. (2015) Enzymes Approved for Human Therapy: Indications, Mechanisms and Adverse Effects. BioDrugs 29:1, pages 31-55.
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Philip Seeman. (2013) Discovery of why acute lymphoblastic leukaemia cells are killed by asparaginase: Adventures of a young post-doctoral student, Bertha K Madras. Journal of Medical Biography 22:2, pages 90-92.
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Farshad Darvishi HarzeviliFarshad Darvishi Harzevili. 2014. Biotechnological Applications of the Yeast Yarrowia lipolytica. Biotechnological Applications of the Yeast Yarrowia lipolytica 17 74 .

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