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Blood and Lymphatic Cancer: Targets and Therapy Volume 12, 2022 - Issue
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Review

Asparaginase in the Treatment of Acute Lymphoblastic Leukemia in Adults: Current Evidence and Place in Therapy

Krishna R Juluri1 Department of Medicine, University of Washington School of Medicine, Seattle, WA, USA;2 Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA;3 Seattle Cancer Care Alliance, Seattle, WA, USA
,
Chloe Siu3 Seattle Cancer Care Alliance, Seattle, WA, USA;4 Department of Pharmacy, University of Washington School of Pharmacy, Seattle, WA, USA
&
Ryan D Cassaday1 Department of Medicine, University of Washington School of Medicine, Seattle, WA, USA;2 Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA;3 Seattle Cancer Care Alliance, Seattle, WA, USACorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-3424-2425
ORCID Icon
Pages 55-79 | Published online: 30 May 2022

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Amani Alqahtani, Diala Alhousari, Amir Ali, George Yaghmour, Etan Orgel, Emily Curran, Wendy Stock, Deepa Bhojwani & Houda Alachkar. (2023) Asparaginase toxicity in Hispanic adult and pediatric patients with acute lymphoblastic leukemia: current understanding. Expert Opinion on Drug Metabolism & Toxicology 19:6, pages 357-366.
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Articles from other publishers (4)

Natalia Dobryakova, Dmitry Zhdanov, Maria Dumina, Svetlana Aleksandrova, Marina Pokrovskaya, Alexander Genin, Anastasia Shishparenok, Alexander Zhgun & Elena Vadimovna Kudryashova. (2023) Thermal Inactivation Mechanism and Structural Features Providing Enhanced Thermal Stability of Hyperthermophilic Thermococcus sibiricus L-Asparaginase in Comparison with Mesophilic and Thermophilic L-Asparaginases. Catalysts 13:5, pages 832.
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Jonathan Blachier, Aurore Cleret, Nathalie Guerin, Clara Gil, Jean-Marc Fanjat, Florian Tavernier, Laura Vidault, Fanny Gallix, Nicolas Rama, Rodrigue Rossignol, Diana Piedrahita, Aurély Andrivon, Marie Châlons-Cottavoz, Karine Aguera, Fabien Gay, Françoise Horand & Bastien Laperrousaz. (2023) L-asparaginase anti-tumor activity in pancreatic cancer is dependent on its glutaminase activity and resistance is mediated by glutamine synthetase. Experimental Cell Research 426:2, pages 113568.
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Todd William MuddJr.Jr., Ashley Danielle Fox, Mark Ghaly & Amany Keruakous. (2023) Case report: Hyperosmolar hyperglycemic syndrome secondary to PEG-asparaginase-induced hypertriglyceridemia and pancreatitis. Frontiers in Oncology 12.
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Muzuni .Suriana .Nur Yanti & Ardiansyah .. (2022) Phenotypic Characterization and Identification of Potential L-Asparaginase-Producing Thermohalophilic Bacteria from Wawolesea Hot Spring, North Konawe, Southeast Sulawesi, Indonesia. Pakistan Journal of Biological Sciences 25:11, pages 1021-1032.
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