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Clinical, Cosmetic and Investigational Dermatology Volume 13, 2020 - Issue
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Research Letter

Efficacy and Safety of Sonidegib in Adult Patients with Nevoid Basal Cell Carcinoma Syndrome (Gorlin Syndrome): Results from a Phase 2, Double-Blind, Randomized Trial

John T Lear1 Manchester Royal Infirmary, Manchester, UKCorrespondence[email protected]
,
Axel Hauschild2 Klinik Für Dermatologie, Venerologie Und Allergologie Universitätsklinikum Schleswig-Holstein, Kiel, GermanyORCID Iconhttps://orcid.org/0000-0002-1212-9587
ORCID Icon,
Eggert Stockfleth3 Universitätshautklinik Bochum, Bochum, Germany
,
Nicholas Squittieri4 Sun Pharmaceutical Industries, Inc., Princeton, NJ, USA
,
Nicole Basset-Seguin5 Department of Dermatology, Hôpital Saint Louis, Paris, FranceORCID Iconhttps://orcid.org/0000-0002-9136-1244
ORCID Icon &
Reinhard Dummer6 Skin Cancer Center University Hospital, Zürich, SwitzerlandORCID Iconhttps://orcid.org/0000-0002-2279-6906
ORCID Icon
Pages 117-121 | Published online: 03 Feb 2020

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Alessia Villani, Eleonora Cinelli, Gabriella Fabbrocini, Aimilios Lallas & Massimiliano Scalvenzi. (2020) Hedgehog inhibitors in the treatment of advanced basal cell carcinoma: risks and benefits. Expert Opinion on Drug Safety 19:12, pages 1585-1594.
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Articles from other publishers (9)

Alex Nguyen, Pingxing Xie, Ivan V. Litvinov & Philippe Lefrançois. (2023) Efficacy and Safety of Sonic Hedgehog Inhibitors in Basal Cell Carcinomas: An Updated Systematic Review and Meta-analysis (2009–2022). American Journal of Clinical Dermatology 24:3, pages 359-374.
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O.M. Moreno-Arrones, S. Béa-Ardebol, F. Mayo-Martinez, G. Pérez-Pastor, I. Torres-Navarro, M. Bonfill-Ortí, G. Deza, V. Ruiz-Salas, E. Masferrer, C. Feal, L. Turrión-Merino, A. Toll, M. Yébenes, S. Galiano-Mejías, A. Jaka, C. Ferrandiz-Pulido, A. Florez, N. Hernández-Hernández, R. Fernández-de-Misa, L. Rios-Buceta & O. Sanmartin. (2023) Sonidegib as a Locally Advanced Basal Cell Carcinoma Therapy in Real-life Clinical Setting: A National Multicentre Study. Actas Dermo-Sifiliográficas.
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Ruolan Xia, Maosen Xu, Jing Yang & Xuelei Ma. (2022) The role of Hedgehog and Notch signaling pathway in cancer. Molecular Biomedicine 3:1.
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Babette J.A. Verkouteren, Kelly A.E. Sinx, Marie G.H.C. Reinders, Maureen J.B. Aarts & Klara Mosterd. (2022) Update on Hedgehog Pathway Inhibitor Therapy for Patients with Basal Cell Naevus Syndrome or High-frequency Basal Cell Carcinoma. Acta Dermato-Venereologica 102, pages adv00741.
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B.J.A. Verkouteren, B. Cosgun, M.G.H.C. Reinders, P.A.W.K. Kessler, R.J. Vermeulen, M. Klaassens, S. Lambrechts, J.R. van Rheenen, M. van Geel, M. Vreeburg & K. Mosterd. (2021) A guideline for the clinical management of basal cell naevus syndrome (Gorlin–Goltz syndrome)*. British Journal of Dermatology 186:2, pages 215-226.
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Jian Yi Chai, Vaisnevee Sugumar, Mohammed Abdullah Alshawsh, Won Fen Wong, Aditya Arya, Pei Pei Chong & Chung Yeng Looi. (2021) The Role of Smoothened-Dependent and -Independent Hedgehog Signaling Pathway in Tumorigenesis. Biomedicines 9:9, pages 1188.
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O. San Martín, B. Llombart, G. Carretero Hernandez, Á. Flórez Menéndez, R. Botella-Estrada, E. Herrera Ceballos & S. Puig. (2021) Sonidegib in the Treatment of Locally Advanced Basal Cell Carcinoma. Actas Dermo-Sifiliográficas (English Edition) 112:4, pages 295-301.
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O. Sanmartín, B. Llombart, G. Carretero Hernández, Á. Flórez Menéndez, R. Botella-Estrada, E. Herrera Ceballos & S. Puig. (2021) Sonidegib en el tratamiento del carcinoma basocelular localmente avanzado. Actas Dermo-Sifiliográficas 112:4, pages 295-301.
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Alessia Villani, Gabriella Fabbrocini, Claudia Costa & Massimiliano Scalvenzi. (2020) Sonidegib: Safety and Efficacy in Treatment of Advanced Basal Cell Carcinoma. Dermatology and Therapy 10:3, pages 401-412.
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