Citations (45)
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A. Smeriglio, S. Ragusa, M. T. Monforte, V. D’angelo & C. Circosta. (2019) Phytochemical analysis and evaluation of antioxidant and anti-acetylcholinesterase activities of Euphorbia dendroides L. (Euphorbiaceae) latex. Plant Biosystems - An International Journal Dealing with all Aspects of Plant Biology 153:4, pages 498-505.
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Rosa Ortega del Olmo & Rafael Salido-Vallejo. (2018) Ingenol mebutate for the treatment of actinic keratosis: effectiveness and safety in 246 patients treated in real-life clinical practice. Journal of Dermatological Treatment 29:4, pages 393-399.
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Alicia D. Bucko, Michael Jarratt, Dowling B. Stough, Laerke Kyhl, John Villumsen & Anders Hall. (2018) Pharmacokinetics of ingenol mebutate gel under maximum use conditions in large treatment areas. Journal of Dermatological Treatment 29:1, pages 74-79.
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Peter Foley, Eggert Stockfleth, Ketty Peris, Nicole Basset-Seguin, Rino Cerio, José Antonio Sanches, Carlos Guillen, Emily Farrington & Mark Lebwohl. (2016) Adherence to topical therapies in actinic keratosis: A literature review. Journal of Dermatological Treatment 27:6, pages 538-545.
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William C. Hanke, Jenny M. Norlin, Kim Mark Knudsen, Thomas Larsson & Stephen Stone. (2016) Quality of life in treatment of AK: Treatment burden of ingenol mebutate gel is small and short lasting. Journal of Dermatological Treatment 27:5, pages 450-455.
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Brian Berman. (2015) Safety and tolerability of ingenol mebutate in the treatment of actinic keratosis. Expert Opinion on Drug Safety 14:12, pages 1969-1978.
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Articles from other publishers (39)
Jian-Yi Huang, Ying Yang, Hong Liang, Xue-Xue Pu, Ying-Yao Li, Min Cai, Feng Guo, Lin Liu, Ming-Ming Cao, Ying Yan, Yuanyuan Cheng, Ying-Tong Di & Xiao-Jiang Hao. (2023) Pepluenone, a new pepluane-type diterpenoid with inhibitory activity on the release of NO from the whole plant of Euphorbia peplus L.. Tetrahedron Letters, pages 154550.
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W. Ben Hmouda, F. Bafort & M.H. Jijakli. (2023)
Effects of heat stress on
Euphorbia peplus
growth in hydroponics and subsequent ingenol production
. Acta Horticulturae:1358, pages 327-332.
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Ana Laura V. Alves, Luciane S. da Silva, Camila A. Faleiros, Viviane A. O. Silva & Rui M. Reis. (2022) The Role of Ingenane Diterpenes in Cancer Therapy: From Bioactive Secondary Compounds to Small Molecules. Natural Product Communications 17:7, pages 1934578X2211056.
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Françoise Bafort, Stephan Kohnen, Etienne Maron, Ayoub Bouhadada, Nicolas Ancion, Nathalie Crutzen & M. Haïssam Jijakli. (2022) The Agro-Economic Feasibility of Growing the Medicinal Plant Euphorbia peplus in a Modified Vertical Hydroponic Shipping Container. Horticulturae 8:3, pages 256.
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Gabriel Alves Bonafé, Matheus Negri Boschiero, André Rodrigues Sodré, Jussara Vaz Ziegler, Thalita Rocha & Manoela Marques Ortega. (2022) Natural Plant Compounds: Does Caffeine, Dipotassium Glycyrrhizinate, Curcumin, and Euphol Play Roles as Antitumoral Compounds in Glioblastoma Cell Lines?. Frontiers in Neurology 12.
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Maria-Eleni Grafakou, Christina Barda, Joerg Heilmann & Helen Skaltsa. (2021)
Macrocyclic Diterpenoid Constituents of
Euphorbia deflexa
, an Endemic Spurge from Greece
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Antonella Smeriglio, Marcella Denaro, Domenico Trombetta, Salvatore Ragusa & Clara Circosta. (2021) New Insights on Euphorbia dendroides L. (Euphorbiaceae): Polyphenol Profile and Biological Properties of Hydroalcoholic Extracts from Aerial Parts. Plants 10:8, pages 1621.
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Yan-Ni Chen, Xiao Ding, Dong-Mei Li, Qing-Yun Lu, Shuai Liu, Ying-Yao Li, Ying-Tong Di, Xin Fang & Xiao-Jiang Hao. (2021) Jatrophane Diterpenoids from the Seeds of Euphorbia peplus with Potential Bioactivities in Lysosomal-Autophagy Pathway. Natural Products and Bioprospecting 11:3, pages 357-364.
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Yan-Ni Chen, Xiao Ding, Dong-Mei Li, Mao Sun, Lei Yang, Yu Zhang, Ying-Tong Di, Xin Fang & Xiao-Jiang Hao. (2021)
Diterpenoids with an unprecedented ring system from
Euphorbia peplus
and their activities in the lysosomal-autophagy pathway
. Organic & Biomolecular Chemistry 19:7, pages 1541-1545.
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Yan-Ni Chen, Xiao Ding, Qing-Yun Lu, Dong-Mei Li, Bo-Ting Li, Shuai Liu, Lei Yang, Yu Zhang, Ying-Tong Di, Xin Fang & Xiao-Jiang Hao. (2020) Macrocyclic diterpenoids from the seeds of Euphorbia peplus with potential activity in inducing lysosomal biogenesis. Bioorganic Chemistry 105, pages 104464.
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Melanie‐Jayne R. Howes, Cassandra L. Quave, Jérôme Collemare, Evangelos C. Tatsis, Danielle Twilley, Ermias Lulekal, Andrew Farlow, Liping Li, María‐Elena Cazar, Danna J. Leaman, Thomas A. K. Prescott, William Milliken, Cathie Martin, Marco Nuno De Canha, Namrita Lall, Haining Qin, Barnaby E. Walker, Carlos Vásquez‐Londoño, Bob Allkin, Malin Rivers, Monique S. J. Simmonds, Elizabeth Bell, Alex Battison, Juri Felix, Felix Forest, Christine Leon, China Williams & Eimear Nic Lughadha. (2020) Molecules from nature: Reconciling biodiversity conservation and global healthcare imperatives for sustainable use of medicinal plants and fungi. PLANTS, PEOPLE, PLANET 2:5, pages 463-481.
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Jason K. Cullen, Jacinta L. Simmons, Peter G. Parsons & Glen M. Boyle. (2020) Topical treatments for skin cancer. Advanced Drug Delivery Reviews 153, pages 54-64.
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Silva, Rosa, Tansini, Martinho, Tanuri, Evangelista, Cruvinel Carloni, Lima, Pianowski & Reis. (2019) Semi-Synthetic Ingenol Derivative from Euphorbia tirucalli Inhibits Protein Kinase C Isotypes and Promotes Autophagy and S-phase Arrest on Glioma Cell Lines. Molecules 24:23, pages 4265.
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Salehi, Iriti, Vitalini, Antolak, Pawlikowska, Kręgiel, Sharifi-Rad, Oyeleye, Ademiluyi, Czopek, Staniak, Custódio, Coy-Barrera, Segura-Carretero, Cádiz-Gurrea, Capasso, Cho & Seca. (2019) Euphorbia-Derived Natural Products with Potential for Use in Health Maintenance. Biomolecules 9:8, pages 337.
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Madeleine Ernst, Kyo Bin Kang, Andrés Mauricio Caraballo-Rodríguez, Louis-Felix Nothias, Joe Wandy, Christopher Chen, Mingxun Wang, Simon Rogers, Marnix H. Medema, Pieter C. Dorrestein & Justin J.J. van der Hooft. (2019) MolNetEnhancer: Enhanced Molecular Networks by Integrating Metabolome Mining and Annotation Tools. Metabolites 9:7, pages 144.
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Madeleine Ernst, Louis-Félix Nothias, Justin J. J. van der Hooft, Ricardo R. Silva, C. Haris Saslis-Lagoudakis, Olwen M. Grace, Karen Martinez-Swatson, Gustavo Hassemer, Luís A. Funez, Henrik T. Simonsen, Marnix H. Medema, Dan Staerk, Niclas Nilsson, Paola Lovato, Pieter C. Dorrestein & Nina Rønsted. (2019) Assessing Specialized Metabolite Diversity in the Cosmopolitan Plant Genus Euphorbia L.. Frontiers in Plant Science 10.
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Luiz Gameiro, Luis Fernando Requejo Tovo, José Antonio Sanches Júnior & Ivan Aprahamian. (2019) Treatment of actinic keratoses and cancerization field of the face and scalp with 0.015% ingenol mebutate gel in Brazilian individuals: safety, tolerability and patients' perspectives. Anais Brasileiros de Dermatologia 94:3, pages 313-319.
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Claudio Frezza, Alessandro Venditti, Fabio Sciubba, Pierpaolo Tomai, Marika Antonetti, Marco Franceschin, Maria Enrica Di Cocco, Alessandra Gentili, Maurizio Delfini, Mauro Serafini & Armandodoriano Bianco. (2018) Phytochemical profile of Euphorbia peplus L. collected in Central Italy and NMR semi-quantitative analysis of the diterpenoid fraction. Journal of Pharmaceutical and Biomedical Analysis 160, pages 152-159.
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Audrey S. Wang & Oliver Dreesen. (2018) Biomarkers of Cellular Senescence and Skin Aging. Frontiers in Genetics 9.
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E. Stockfleth, C.A. Harwood, C. Serra-Guillén, T. Larsson, M.L. Østerdal & T. Skov. (2018) Phase IV head-to-head randomized controlled trial comparing ingenol mebutate 0·015% gel with diclofenac sodium 3% gel for the treatment of actinic keratosis on the face or scalp. British Journal of Dermatology 178:2, pages 433-442.
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Harald P. M. Gollnick. (2017) Die Prävention und Therapie Aktinischer KeratosenPrevention and therapy of actinic keratoses. MMW - Fortschritte der Medizin 159:8, pages 60-68.
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T. Gracia-Cazaña, S. González & Y. Gilaberte. (2016) Resistance of Nonmelanoma Skin Cancer to Nonsurgical Treatments. Part I: Topical Treatments. Actas Dermo-Sifiliográficas (English Edition) 107:9, pages 730-739.
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T. Gracia-Cazaña, S. González & Y. Gilaberte. (2016) Resistencias al tratamiento no quirúrgico en cáncer cutáneo no melanoma. Parte I: tratamientos tópicos. Actas Dermo-Sifiliográficas 107:9, pages 730-739.
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Andrés M. Erlendsson, Daniel Thaysen-Petersen, Christiane Bay, Catharina M. Lerche, Peter A. Philipsen, Hans Christian Wulf, John R. Zibert & Merete Hædersdal. (2016) Repeated treatments with ingenol mebutate for prophylaxis of UV-induced squamous cell carcinoma in hairless mice. Journal of Photochemistry and Photobiology B: Biology 163, pages 144-149.
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Steffen Emmert, Holger A. Haenssle, John R. Zibert, Margarete Schön, Andreas Hald, Maria H. Hansen, Thomas Litman & Michael P. Schön. (2016) Tumor-Preferential Induction of Immune Responses and Epidermal Cell Death in Actinic Keratoses by Ingenol Mebutate. PLOS ONE 11:9, pages e0160096.
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Madeleine Ernst, C. Haris Saslis-Lagoudakis, Olwen M. Grace, Niclas Nilsson, Henrik Toft Simonsen, James W. Horn & Nina Rønsted. (2016) Evolutionary prediction of medicinal properties in the genus Euphorbia L.. Scientific Reports 6:1.
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R.E. Schopf. (2016) Ingenol mebutate gel is effective against anogenital warts - a case series in 17 patients. Journal of the European Academy of Dermatology and Venereology 30:6, pages 1041-1043.
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Andrés Már Erlendsson, Katrine Elisabeth Karmisholt, Christina Skovbølling Haak, Ida-Marie Stender & Merete Haedersdal. (2016) Topical corticosteroid has no influence on inflammation or efficacy after ingenol mebutate treatment of grade I to III actinic keratoses (AK): A randomized clinical trial. Journal of the American Academy of Dermatology 74:4, pages 709-715.
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J.A. Moreno Romero, A. Campoy, N. Perez, F. Garcia & R. Grimalt. (2015) Rapidly-growing squamous cell carcinoma shortly after treatment with ingenol mebutate for actinic keratoses: report of two cases. British Journal of Dermatology 173:6, pages 1514-1517.
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Madeleine Ernst, Olwen M. Grace, C. Haris Saslis-Lagoudakis, Niclas Nilsson, Henrik Toft Simonsen & Nina Rønsted. (2015) Global medicinal uses of Euphorbia L. (Euphorbiaceae). Journal of Ethnopharmacology 176, pages 90-101.
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A. Batalla, Á. Flórez, C. Feal, G. Peón, M.T. Abalde, L. Salgado-Boquete & C. de la Torre. (2015) Clinical Response to Ingenol Mebutate in Patients With Actinic Keratoses. Actas Dermo-Sifiliográficas (English Edition) 106:10, pages e55-e61.
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A. Batalla, Á. Flórez, C. Feal, G. Peón, M.T. Abalde, L. Salgado-Boquete & C. de la Torre. (2015) Respuesta a ingenol mebutato en los pacientes con queratosis actínicas en la práctica clínica. Actas Dermo-Sifiliográficas 106:10, pages e55-e61.
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John Powell, Taleah Farasyn, Kathleen Köck, Xiaojie Meng, Sonia Pahwa, Kim L. R. Brouwer & Wei Yue. (2014) Novel Mechanism of Impaired Function of Organic Anion-Transporting Polypeptide 1B3 in Human Hepatocytes: Post-Translational Regulation of OATP1B3 by Protein Kinase C Activation. Drug Metabolism and Disposition 42:11, pages 1964-1970.
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Giuseppe Micali, Francesco Lacarrubba, Maria Rita Nasca & Robert A. Schwartz. (2014) Topical pharmacotherapy for skin cancer. Journal of the American Academy of Dermatology 70:6, pages 965.e1-965.e12.
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Nicholas J Collier, Faisal R Ali & John T Lear. (2014) Ingenol mebutate: a novel treatment for actinic keratosis. Clinical Practice 11:3, pages 295-306.
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Gunnar Grue-Sørensen, Xifu Liang, Kristoffer Månsson, Per Vedsø, Morten Dahl Sørensen, Anke Soor, Martin Stahlhut, Malene Bertelsen, Karen Margrethe Engell & Thomas Högberg. (2014) Synthesis, biological evaluation and SAR of 3-benzoates of ingenol for treatment of actinic keratosis and non-melanoma skin cancer. Bioorganic & Medicinal Chemistry Letters 24:1, pages 54-60.
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Xifu Liang, Gunnar Grue-Sørensen, Kristoffer Månsson, Per Vedsø, Anke Soor, Martin Stahlhut, Malene Bertelsen, Karen Margrethe Engell & Thomas Högberg. (2013) Syntheses, biological evaluation and SAR of ingenol mebutate analogues for treatment of actinic keratosis and non-melanoma skin cancer. Bioorganic & Medicinal Chemistry Letters 23:20, pages 5624-5629.
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