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Original Research

Rikkunshito, a traditional Japanese medicine, suppresses cisplatin-induced anorexia in humans

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Pages 291-296 | Published online: 12 Dec 2011

Keep up to date with the latest research on this topic with citation updates for this article.

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Xipei Wu, Yongzhao Dai & Ke Nie. (2022) Research Progress of Liujunzi Decoction in the Treatment of Tumor-Associated Anorexia. Drug Design, Development and Therapy 16, pages 1731-1741.
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Hiroshi Yamaguchi, Yasutoshi Kimura, Masafumi Imamura, Minoru Nagayama, Tatsuya Ito, Daisuke Kyuno, Tsuyoshi Kono, Akina Kimura, Emi Akizuki, Toshihiko Nishidate, Kenji Okita, Takayuki Nobuoka, Toru Mizuguchi, Koichi Hirata & Ichiro Takemasa. (2020) Effect of Rikkunshito, a Traditional Japanese Herbal Medicine, on Delayed Gastric Emptying and Oral Dietary Intake After Pancreaticoduodenectomy: A Prospective, Randomized, Single-Center, Open-Labeled Study. Clinical and Experimental Gastroenterology 13, pages 577-587.
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Shinya Kajiura, Ayumu Hosokawa, Hiroki Yoshita, Akira Ueda, Takayuki Ando, Haruka Fujinami, Jun Nishikawa, Kohei Ogawa & Toshiro Sugiyama. (2015) Preventive effect of R ikkunshito, a traditional J apanese medicine, on chemotherapy‐induced nausea and vomiting with cisplatin: C ase series . Traditional & Kampo Medicine 2:1, pages 8-13.
Crossref
Shunsuke Ohnishi & Hiroshi Takeda. (2015) Herbal medicines for the treatment of cancer chemotherapy-induced side effects. Frontiers in Pharmacology 6.
Crossref
U. Eberhard. (2015) Kampo bei Magen- und Darmerkrankungen: Teil 1: Beschwerden im oberen Verdauungstrakt. Deutsche Zeitschrift für Akupunktur 58:1, pages 44-46.
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Kiyoshi Terawaki, Yumi SawadaYohei KashiwaseHirofumi HashimotoMitsuhiro YoshimuraMasami SuzukiKanako MiyanoYuka SudoSeiji ShiraishiYoshikazu HigamiKazuyoshi YanagiharaYoshio Kase, Yoichi UetaYasuhito Uezono. (2014) New cancer cachexia rat model generated by implantation of a peritoneal dissemination-derived human stomach cancer cell line. American Journal of Physiology-Endocrinology and Metabolism 306:4, pages E373-E387.
Crossref
Masako Nishimura, Naoki Kakihara, Kota Asano, Eiichirou Kanda, Hideaki Kawabata, Mariko Nose, Yoko Nishitani, Tadashi Mikami & Osamu Ikawa. (2014) Case regarding Traditional Japanese Medicine’s effectiveness for nausea and vomit caused by peritonitis carcinomatosa. Palliative Care Research 9:4, pages 533-537.
Crossref
Mohammad Bashashati & Richard W. McCallum. (2014) Neurochemical mechanisms and pharmacologic strategies in managing nausea and vomiting related to cyclic vomiting syndrome and other gastrointestinal disorders. European Journal of Pharmacology 722, pages 79-94.
Crossref
Mitsuhiro Yoshimura, Takanori Matsuura, Junichi Ohkubo, Motoko Ohno, Takashi Maruyama, Toru Ishikura, Hirofumi Hashimoto, Tetsuya Kakuma, Hironobu Yoshimatsu, Kiyoshi Terawaki, Yasuhito Uezono & Yoichi Ueta. (2013) The gene expression of the hypothalamic feeding-regulating peptides in cisplatin-induced anorexic rats. Peptides 46, pages 13-19.
Crossref
Kazunari Tominaga & Tetsuo Arakawa. (2013) Kampo medicines for gastrointestinal tract disorders: a review of basic science and clinical evidence and their future application. Journal of Gastroenterology 48:4, pages 452-462.
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Yasuo MORIMOTO, Shimpei WATANABE, Seiwa MICHIHARA, Hisayoshi NORIMOTO, Keiko NAKAJIMA, Motoi HIURA & Toshiki OKUBO. (2013) Effects of Rikkunshito on Cisplatin-induced Delay in Gastric Emptying in Rats. Kampo Medicine 64:3, pages 150-159.
Crossref
Tomohisa Hattori, Koji Yakabi & Hiroshi Takeda. 2013. Anorexia. Anorexia 301 317 .
Hiroshi Takeda, Shuichi Muto, Koji Nakagawa, Shunsuke Ohnishi, Chiharu Sadakane, Yayoi Saegusa, Miwa Nahata, Tomohisa Hattori & Masahiro Asaka. 2012. Ghrelin. Ghrelin 333 351 .