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Original Research

Barrier effect of Esoxx® on esophageal mucosal damage: experimental study on ex-vivo swine model

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Pages 103-107 | Published online: 11 Jun 2012

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (8)

Ai Wei Lim, Nicholas J. Talley, Marjorie M. Walker, Gert Storm & Susan Hua. (2023) Current status and advances in esophageal drug delivery technology: influence of physiological, pathophysiological and pharmaceutical factors. Drug Delivery 30:1.
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Vincenzo Savarino, Elisa Marabotto, Patrizia Zentilin, Nicola De Bortoli, Pierfrancesco Visaggi, Manuele Furnari, Giorgia Bodini, Edoardo Giannini & Edoardo Savarino. (2023) How safe are heartburn medications and who should use them?. Expert Opinion on Drug Safety 22:8, pages 643-652.
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Laura Ceriotti, Paolo Buratti, Enrico Stefano Corazziari & Marisa Meloni. (2022) Protective Mechanisms of Liquid Formulations for Gastro-Oesophageal Reflux Disease in a Human Reconstructed Oesophageal Epithelium Model. Medical Devices: Evidence and Research 15, pages 143-152.
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Vincenzo Savarino, Elisa Marabotto, Patrizia Zentilin, Maria Giulia Demarzo, Nicola de Bortoli & Edoardo Savarino. (2021) Pharmacological Management of Gastro-Esophageal Reflux Disease: An Update of the State-of-the-Art. Drug Design, Development and Therapy 15, pages 1609-1621.
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Marisa Meloni, Paolo Buratti, Francesco Carriero & Laura Ceriotti. (2021) In Vitro Modelling of Barrier Impairment Associated with Gastro-Oesophageal Reflux Disease (GERD). Clinical and Experimental Gastroenterology 14, pages 361-373.
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Roberta Salaroli, Domenico Ventrella, Chiara Bernardini, Alberto Elmi, Augusta Zannoni, Maria Laura Bacci, Monica Forni, Fiorella Calanni, Antonella Ferrieri & Fabio Baldi. (2020) Barrier Effect of a New Topical Agent on Damaged Esophageal Mucosa: Experimental Study on an ex vivo Swine Model. Clinical and Experimental Gastroenterology 13, pages 569-576.
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Vincenzo Savarino, Elisa Marabotto, Patrizia Zentilin, Manuele Furnari, Giorgia Bodini, Costanza De Maria, Salvatore Tolone, Nicola De Bortoli, Marzio Frazzoni & Edoardo Savarino. (2020) Pathophysiology, diagnosis, and pharmacological treatment of gastro-esophageal reflux disease. Expert Review of Clinical Pharmacology 13:4, pages 437-449.
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Edoardo Savarino, Patrizia Zentilin, Elisa Marabotto, Giorgia Bodini, Marco Della Coletta, Marzio Frazzoni, Nicola de Bortoli, Irene Martinucci, Salvatore Tolone, Gaia Pellegatta & Vincenzo Savarino. (2017) A review of pharmacotherapy for treating gastroesophageal reflux disease (GERD). Expert Opinion on Pharmacotherapy 18:13, pages 1333-1343.
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Articles from other publishers (23)

Yeray Brito-Casillas, María José Caballero, Luisa Hernández-Baraza, Rosa María Sánchez-Hernández, Juan Carmelo Betancort-Acosta & Ana M. Wägner. (2023) Ex vivo evaluation of adhesive strength and barrier effect of a novel treatment for esophagitis. Gastroenterología y Hepatología 46:6, pages 455-461.
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Palittiya Sintusek, Mohamed Mutalib & Nikhil Thapar. (2023) Gastroesophageal reflux disease in children: What’s new right now?. World Journal of Gastrointestinal Endoscopy 15:3, pages 84-102.
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Vincenzo Savarino, Elisa Marabotto, Patrizia Zentilin, Manuele Furnari, Giorgia Bodini, Edoardo Giovanni Giannini & Edoardo Vincenzo Savarino. (2023) Gastrointestinal functional disorders can benefit from the use of medical devices made of substances. Frontiers in Drug Safety and Regulation 3.
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Rocco Malivindi, Francesco Patitucci, Sabrina Prete, Marco Dattilo, Adele Elisabetta Leonetti, Norma Scigliano, Ortensia Ilaria Parisi & Francesco Puoci. (2022) Efficacy and safety assessment of PIMIN050 raft-forming system as medical device based on Citrus sinensis and Crassostrea gigas for the management of gastroesophageal reflux disease. Journal of Drug Delivery Science and Technology 78, pages 103986.
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Natalia V. Bakulina, Sergey V. Tikhonov, Yulia G. Topalova, Tatyana A. Ilchishina & Roman O. Vasiliev. (2022) Esophagoprotective therapy in patients with erosive esophagitis. Terapevticheskii arkhiv 94:8, pages 985-991.
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Tiziana M. G. Pecora, Ortensia Ilaria Parisi, Walter Bertin, Barbara Ragazzo, Marco Dattilo, Norma Scigliano, Rocco Malivindi, Fabio Amone & Francesco Puoci. (2022) Barrier effect and wound healing activity of the medical device REF-FTP78 in the treatment of gastroesophageal reflux disease. Scientific Reports 12:1.
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Claudio Romano & Carmelo Scarpignato. (2022) Pharmacologic treatment of GERD in adolescents: Is esophageal mucosal protection an option?. Therapeutic Advances in Gastroenterology 15, pages 175628482211153.
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Sinith Withanage, Artemii Savin, Valeria Nikolaeva, Aleksandra Kiseleva, Marina Dukhinova, Pavel Krivoshapkin & Elena Krivoshapkina. (2021) Native Spider Silk-Based Antimicrobial Hydrogels for Biomedical Applications. Polymers 13:11, pages 1796.
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GL Muntingh. (2021) Gastro-oesophageal reflux disease: extinguishing that fire. South African General Practitioner 2:5, pages 178-183.
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Chiara Agostinis, Fleur Bossi, Alessandro Mangogna, Andrea Balduit, Micol Pacor, Emiliana Giacomello, Beatrice Belmonte, Daniele Greco, Vito Rodolico, Dario Voinovich, Francesco De Seta, Giuseppe Ricci & Roberta Bulla. (2020) Protective and regenerative effects of a novel medical device against esophageal mucosal damage using in vitro and ex vivo models. Biomedicine & Pharmacotherapy 131, pages 110752.
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V. T. Ivashkin, I. V. Maev, A. S. Trukhmanov, T. L. Lapina, O. A. Storonova, O. V. Zayratyants, O. B. Dronova, Yu. A. Kucheryavyy, S. S. Pirogov, R. G. Sayfutdinov, Yu. P. Uspenskiy, A. A. Sheptulin, D. N. Andreev & D. E. Rumyantseva. (2020) Recommendations of the Russian Gastroenterological Association in Diagnosis and Treatment of Gastroesophageal Reflux Disease. Russian Journal of Gastroenterology, Hepatology, Coloproctology 30:4, pages 70-97.
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Stefano Siboni, Marco Sozzi, Matteo Capuzzo, Alberto Buogo, Carlo Galdino Riva, Davide Ferrari & Luigi Bonavina. (2020) Combined pharmacologic antireflux therapy after esophagectomy: effect on symptoms and endoscopic findings at 1-year follow-up. European Surgery 52:3, pages 118-122.
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Martina Bertocchi, Antonella Rigillo, Alberto Elmi, Domenico Ventrella, Camilla Aniballi, Diana G. Scorpio, Maurizio Scozzoli, Giuliano Bettini, Monica Forni & Maria Laura Bacci. (2020) Preliminary Assessment of the Mucosal Toxicity of Tea Tree (Melaleuca alternifolia) and Rosemary (Rosmarinus officinalis) Essential Oils on Novel Porcine Uterus Models. International Journal of Molecular Sciences 21:9, pages 3350.
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Fahmi Shibli, Yoshitaka Kitayama & Ronnie Fass. (2020) Novel Therapies for Gastroesophageal Reflux Disease: Beyond Proton Pump Inhibitors. Current Gastroenterology Reports 22:4.
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Domenico Ventrella, Roberta SalaroliAlberto Elmi, Giacomo CarnevaliMonica Forni, Fabio Baldi & Maria Laura Bacci. (2020) A novel ex vivo porcine model of acid-induced esophageal damage for preliminary functional evaluations of anti-gastroesophageal reflux disease medical devices. Veterinary World 13:12, pages 2728-2735.
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I V Maev, D N Andreev, Yu A Kucheryavyy & R I Shaburov. (2019) Current advances in the treatment of gastroesophageal reflux disease: a focus on esophageal protection. Terapevticheskii arkhiv 91:8, pages 4-11.
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Nathan A. Rohner, Steve J. Schomisch, Jeffrey M. Marks & Horst A. von Recum. (2019) Cyclodextrin Polymer Preserves Sirolimus Activity and Local Persistence for Antifibrotic Delivery over the Time Course of Wound Healing. Molecular Pharmaceutics 16:4, pages 1766-1774.
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Tommaso Iannitti, Julio César Morales-Medina, Alberto Merighi, Valentina Boarino, Carmen Laurino, Maria Vadalà & Beniamino Palmieri. (2018) A hyaluronic acid- and chondroitin sulfate-based medical device improves gastritis pain, discomfort, and endoscopic features. Drug Delivery and Translational Research 8:5, pages 994-999.
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Kavi Ramnani, Sayantani Mukherjee & Dana Bisharah. (2018) Review of emerging therapy in refractory GERD- an evidence based approach. Gastroenterology & Hepatology: Open Access 9:4.
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Sławomir Wilczyński & Anna Stolecka-Warzecha. 2018. Polymeric Gels. Polymeric Gels 373 393 .
Carmelo Scarpignato & Luigi Gatta. 2018. Reflux Aspiration and Lung Disease. Reflux Aspiration and Lung Disease 269 291 .
V. Savarino, F. Pace & C. Scarpignato. (2017) Randomised clinical trial: mucosal protection combined with acid suppression in the treatment of non-erosive reflux disease - efficacy of Esoxx, a hyaluronic acid-chondroitin sulphate based bioadhesive formulation. Alimentary Pharmacology & Therapeutics 45:5, pages 631-642.
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Jing Li, Xiaoxin Luke Chen, Anisa Shaker, Tadayuki Oshima, Jing Shan, Hiroto Miwa, Cheng Feng & Jun Zhang. (2016) Contribution of immunomodulators to gastroesophageal reflux disease and its complications: stromal cells, interleukin 4, and adiponectin. Annals of the New York Academy of Sciences 1380:1, pages 183-194.
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