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Original Research

Nonmotor gastrointestinal disorders in older patients with Parkinson’s disease: is there hope?

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Pages 1601-1608 | Published online: 11 Nov 2016

Keep up to date with the latest research on this topic with citation updates for this article.

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Paulina Gątarek & Joanna Kałużna-Czaplińska. (2022) Nutritional aspects in Parkinson’s disease. Critical Reviews in Food Science and Nutrition 62:23, pages 6467-6484.
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Shilan Mozaffari, Shekoufeh Nikfar, Marzieh Daniali & Mohammad Abdollahi. (2020) The pharmacological management of constipation in patients with Parkinson’s disease: a much-needed relief. Expert Opinion on Pharmacotherapy 21:6, pages 701-707.
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Sujith Pavan, Arvind N Prabhu, Sankar Prasad Gorthi, Vignesh Shetty, Vidya Rajesh, Asha Hegde & Mamatha Ballal. (2022) Dietary interventions in Parkinson’s disease: An update. Biomedicine 42:3, pages 422-426.
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Manlian Zhu, Xia Liu, Yiru Ye, Xiumei Yan, Yiwen Cheng, Longyou Zhao, Feng Chen & Zongxin Ling. (2022) Gut Microbiota: A Novel Therapeutic Target for Parkinson’s Disease. Frontiers in Immunology 13.
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Despoina E. Kiousi, Antonia Z. Kouroutzidou, Konstantinos Neanidis, Dimitrios Matthaios, Aglaia Pappa & Alex Galanis. (2022) Evaluating the Role of Probiotics in the Prevention and Management of Age-Related Diseases. International Journal of Molecular Sciences 23:7, pages 3628.
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Vinod Metta, Valentina Leta, Kandadai Rukmini Mrudula, L. K. Prashanth, Vinay Goyal, Rupam Borgohain, Guy Chung-Faye & K. Ray Chaudhuri. (2021) Gastrointestinal dysfunction in Parkinson’s disease: molecular pathology and implications of gut microbiome, probiotics, and fecal microbiota transplantation. Journal of Neurology 269:3, pages 1154-1163.
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Crossref
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Shokufeh Ghasemian Sorboni, Hanieh Shakeri Moghaddam, Reza Jafarzadeh-Esfehani & Saman Soleimanpour. (2022) A Comprehensive Review on the Role of the Gut Microbiome in Human Neurological Disorders. Clinical Microbiology Reviews 35:1.
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Emily M. Klann, Upuli Dissanayake, Anjela Gurrala, Matthew Farrer, Aparna Wagle Shukla, Adolfo Ramirez-Zamora, Volker Mai & Vinata Vedam-Mai. (2022) The Gut–Brain Axis and Its Relation to Parkinson’s Disease: A Review. Frontiers in Aging Neuroscience 13.
Crossref
A. Mohankumar, D. Kalaiselvi, G. Thiruppathi, D. Patteswari, S. Tawata & P. Sundararaj. 2022. Role of Nutrients in Neurological Disorders. Role of Nutrients in Neurological Disorders 17 60 .
G. Divyashri & S. G. Prapulla. 2022. Probiotic Research in Therapeutics. Probiotic Research in Therapeutics 237 254 .
Zakira Naureen, Saima Farooq, Tayyaba Zahoor & Syed Abdullah Gilani. 2022. Microbiome-Gut-Brain Axis. Microbiome-Gut-Brain Axis 383 399 .
Lady Johanna Forero-Rodríguez, Jonathan Josephs-Spaulding, Stefano Flor, Andrés Pinzón & Christoph Kaleta. (2021) Parkinson’s Disease and the Metal–Microbiome–Gut–Brain Axis: A Systems Toxicology Approach. Antioxidants 11:1, pages 71.
Crossref
Xiaoting Zhou, Jiachen Lu, Kehong Wei, Jing Wei, Puyuan Tian, Mengyun Yue, Yun Wang, Daojun Hong, Fangjun Li, Bo Wang, Tingtao Chen & Xin Fang. (2021) Neuroprotective Effect of Ceftriaxone on MPTP-Induced Parkinson’s Disease Mouse Model by Regulating Inflammation and Intestinal Microbiota. Oxidative Medicine and Cellular Longevity 2021, pages 1-15.
Crossref
Sahar Youssef Al-Okbi, Hoda Bakr Mabrok, Enas Sabry K Al-Siedy, Rasha Salah Mohamed & Asmaa Abdelmohsen Ramadan. (2021) Iron status, immune system, and expression of brain divalent metal transporter 1 and dopamine receptors D1 interrelationship in Parkinson’s disease and the role of grape seed and green coffee bean extracts and quercetin in mitigating the disease in rats. Journal of Herbmed Pharmacology 11:1, pages 63-74.
Crossref
Thiago M. C. Pereira, Larissa Z. Côco, Alyne M. M. Ton, Silvana S. Meyrelles, Manuel Campos-Toimil, Bianca P. Campagnaro & Elisardo C. Vasquez. (2021) The Emerging Scenario of the Gut–Brain Axis: The Therapeutic Actions of the New Actor Kefir against Neurodegenerative Diseases. Antioxidants 10:11, pages 1845.
Crossref
Valentina Leta, K. Ray Chaudhuri, Oliver Milner, Guy Chung-Faye, Vinod Metta, Carmine M. Pariante & Alessandra Borsini. (2021) Neurogenic and anti-inflammatory effects of probiotics in Parkinson’s disease: A systematic review of preclinical and clinical evidence. Brain, Behavior, and Immunity 98, pages 59-73.
Crossref
Gabriele Deidda & Manuele Biazzo. (2021) Gut and Brain: Investigating Physiological and Pathological Interactions Between Microbiota and Brain to Gain New Therapeutic Avenues for Brain Diseases. Frontiers in Neuroscience 15.
Crossref
Xueling Zhu, Bo Li, Pengcheng Lou, Tingting Dai, Yang Chen, Aoxiang Zhuge, Yin Yuan & Lanjuan Li. (2021) The Relationship Between the Gut Microbiome and Neurodegenerative Diseases. Neuroscience Bulletin 37:10, pages 1510-1522.
Crossref
Sara Ayman Moustafa, Shrouk Mohamed, Abdelhameed Dawood, Jihan Azar, Ekramy Elmorsy, Noura A. M. Rizk & Mohamed Salama. (2021) Gut brain axis: an insight into microbiota role in Parkinson’s disease. Metabolic Brain Disease 36:7, pages 1545-1557.
Crossref
Shen-Yuan Zheng, Hai-Xia Li, Rui-Chen Xu, Wen-Teng Miao, Ming-Yuan Dai, Song-Tao Ding & Han-Deng Liu. (2021) Potential roles of gut microbiota and microbial metabolites in Parkinson’s disease. Ageing Research Reviews 69, pages 101347.
Crossref
Li Yang Tan, Xin Yi Yeo, Han-Gyu Bae, Delia Pei Shan Lee, Roger C. Ho, Jung Eun Kim, Dong-Gyu Jo & Sangyong Jung. (2021) Association of Gut Microbiome Dysbiosis with Neurodegeneration: Can Gut Microbe-Modifying Diet Prevent or Alleviate the Symptoms of Neurodegenerative Diseases?. Life 11:7, pages 698.
Crossref
Chin-Song Lu, Hsiu-Chen Chang, Yi-Hsin Weng, Chiung-Chu Chen, Yi-Shan Kuo & Ying-Chieh Tsai. (2021) The Add-On Effect of Lactobacillus plantarum PS128 in Patients With Parkinson's Disease: A Pilot Study. Frontiers in Nutrition 8.
Crossref
Elena Cecilia Rosca, Raluca Tudor, Amalia Cornea & Mihaela Simu. (2021) Parkinson’s Disease in Romania: A Scoping Review. Brain Sciences 11:6, pages 709.
Crossref
Yiying Huang, Jinchi Liao, Xu Liu, Yunxiao Zhong, Xiaodong Cai & Ling Long. (2021) Review: The Role of Intestinal Dysbiosis in Parkinson’s Disease. Frontiers in Cellular and Infection Microbiology 11.
Crossref
Marina Lorente-Picón & Ariadna Laguna. (2021) New Avenues for Parkinson’s Disease Therapeutics: Disease-Modifying Strategies Based on the Gut Microbiota. Biomolecules 11:3, pages 433.
Crossref
Marina Boziki, Nikolaos Grigoriadis, Apostolis Papaefthymiou, Michael Doulberis, Stergios A. Polyzos, Emmanuel Gavalas, Georgia Deretzi, Eleni Karafoulidou, Evangelia Kesidou, Charilaos Taloumtzis, Paschalis Theotokis, Electra Sofou, Panagiotis Katsinelos, Elisabeth Vardaka, Ioannis Fludaras, Maria Touloumtzi, Argiro Koukoufiki, Constantina Simeonidou, Christos Liatsos & Jannis Kountouras. (2021) The trimebutine effect on Helicobacter pylori-related gastrointestinal tract and brain disorders: A hypothesis. Neurochemistry International 144, pages 104938.
Crossref
Azliza Ibrahim, Raja Affendi Raja Ali, Mohd Rizal Abdul Manaf, Norfazilah Ahmad, Farah Waheeda Tajurruddin, Wong Zhi Qin, Siti Hajar Md Desa & Norlinah Mohamed Ibrahim. (2020) Multi-strain probiotics (Hexbio) containing MCP BCMC strains improved constipation and gut motility in Parkinson’s disease: A randomised controlled trial. PLOS ONE 15:12, pages e0244680.
Crossref
Gazerani. (2019) Probiotics for Parkinson’s Disease. International Journal of Molecular Sciences 20:17, pages 4121.
Crossref
Jin Gyu Choi, Eugene Huh, Namkwon Kim, Dong-Hyun Kim & Myung Sook Oh. (2019) High-throughput 16S rRNA gene sequencing reveals that 6-hydroxydopamine affects gut microbial environment. PLOS ONE 14:8, pages e0217194.
Crossref
Li-Hao Cheng, Yen-Wenn Liu, Chien-Chen Wu, Sabrina Wang & Ying-Chieh Tsai. (2019) Psychobiotics in mental health, neurodegenerative and neurodevelopmental disorders. Journal of Food and Drug Analysis 27:3, pages 632-648.
Crossref
Despoina Kiousi, Athanasios Karapetsas, Kyriaki Karolidou, Mihalis Panayiotidis, Aglaia Pappa & Alex Galanis. (2019) Probiotics in Extraintestinal Diseases: Current Trends and New Directions. Nutrients 11:4, pages 788.
Crossref
Xin Fang. (2018) Microbial treatment: the potential application for Parkinson’s disease. Neurological Sciences 40:1, pages 51-58.
Crossref
Zhange Yu, Shuai Zhang, Dongdong Wang, Meng Fan, Fuqiang Gao, Wei Sun, Zirong Li & Shiliang Li. (2017) The significance of uric acid in the diagnosis and treatment of Parkinson disease. Medicine 96:45, pages e8502.
Crossref
Nasibeh Ghalandari, Farhad Assarzadegan, Hossein Mahdavi, Elham Jamshidi & Hadi Esmaily. (2022) Using Probiotics to Alleviate Constipation Symptoms in Parkinson Patients: A Systematic Review and Meta-Analysis. SSRN Electronic Journal.
Crossref
Xiaodong Yang, Xiaoqin He, Shaoqing Xu, Yi Zhang, Chengjun Mo, Yiqiu Lai, Yanyan Song, Zheng Yan, Penghui Ai, Yiwei Qian & Qin Xiao. (2022) Effect of <i>Lacticaseibacillus Paracasei</i> Strain Shirota Supplementation on Clinical Responses, Gut Microbiota and Faecal Metabolites in Patients with Parkinson's Disease: A Randomized, Double-Blind, Placebo-Controlled Trial. SSRN Electronic Journal.
Crossref