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Clinical Interventions in Aging Volume 14, 2019 - Issue

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Original Research

Aged kidneys are refractory to autophagy activation in a rat model of renal ischemia-reperfusion injury

Changhui DiaoDepartment of Urology, Renmin Hospital of Wuhan University, Wuhan, Hubei, People’s Republic of China, [email protected]; [email protected]

Lei WangDepartment of Urology, Renmin Hospital of Wuhan University, Wuhan, Hubei, People’s Republic of China, [email protected]; [email protected]Correspondence[email protected] [email protected]

Hao LiuDepartment of Urology, Renmin Hospital of Wuhan University, Wuhan, Hubei, People’s Republic of China, [email protected]; [email protected]

Yang DuDepartment of Urology, Renmin Hospital of Wuhan University, Wuhan, Hubei, People’s Republic of China, [email protected]; [email protected]

Xiuheng LiuDepartment of Urology, Renmin Hospital of Wuhan University, Wuhan, Hubei, People’s Republic of China, [email protected]; [email protected]Correspondence[email protected] [email protected]

Pages 525-534 | Published online: 01 Mar 2019

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Jing Yang, Chaojin Chen, Xiaoyan Miao, Tienan Wang, Yu Guan, Linan Zhang, Sufang Chen, Zheng Zhang, Zhengyuan Xia, Jiayi Kang, Haobo Li, Tinghui Yin, Ziqing Hei & Weifeng Yao. (2023) Injury Site Specific Xenon Delivered by Platelet Membrane‐Mimicking Hybrid Microbubbles to Protect Against Acute Kidney Injury via Inhibition of Cellular Senescence. Advanced Healthcare Materials 12:20.
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Bin Tang, Zhijian Luo, Rong Zhang, Dongmei Zhang, Guojun Nie, Mingxing Li & Yan Dai. (2023) An update on the molecular mechanism and pharmacological interventions for Ischemia-reperfusion injury by regulating AMPK/mTOR signaling pathway in autophagy. Cellular Signalling 107, pages 110665.
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Bushra, Ivon F. Maha, Youbin Yu, Linhua Jiang, Xiao Xie, Suming Zhou & Fei Yin. (2022) Effects of autophagy inhibition by 3-methyladenine on encystation, morphology, and metabolites of Cryptocaryon irritans. Parasitology Research 122:2, pages 509-517.
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Chun-Hsien Chiang, Sin-Jin Li, Ting-Rui Zhang & Ching-Yi Chen. (2022) Long-term dietary restriction ameliorates ageing-related renal fibrosis in male mice by normalizing mitochondrial functions and autophagy. Biogerontology 23:6, pages 731-740.
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Chaojin Chen, Muxu Zheng, Hongbiao Hou, Sijian Fang, Liubing Chen, Jing Yang, Weifeng Yao, Qi Zhang & Ziqing Hei. (2022) Cellular senescence in ischemia/reperfusion injury. Cell Death Discovery 8:1.
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Tomohisa Matsunaga, Maximilian J. Roesel, Andreas Schroeter, Yao Xiao, Hao Zhou & Stefan G. Tullius. (2022) Preserving and rejuvenating old organs for transplantation: novel treatments including the potential of senolytics. Current Opinion in Organ Transplantation 27:5, pages 481-487.
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Gokhan Burcin Kubat, Yasemin Kartal, Ozbeyen Atalay, Oner Ulger, Ozgur Ekinci, Ertugrul Celik, Mukerrem Safali, Murat Urkan, Sevilay Karahan, Mehmet Ozler, Zehra Cicek & Murat Timur Budak. (2021) Investigation of the effect of isolated mitochondria transplantation on renal ischemia-reperfusion injury in rats. Toxicology and Applied Pharmacology 433, pages 115780.
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Monica Chang-Panesso. (2021) Acute kidney injury and aging. Pediatric Nephrology 36:10, pages 2997-3006.
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Yan Zhang, Jinjin Zhang & Shixuan Wang. (2021) The Role of Rapamycin in Healthspan Extension via the Delay of Organ Aging. Ageing Research Reviews 70, pages 101376.
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Qianlong Xue, Lipeng Yang, Hui Wang & Shuchi Han. (2021) Silence of Long Noncoding RNA SNHG14 Alleviates Ischemia/Reperfusion-Induced Acute Kidney Injury by Regulating miR-124-3p/MMP2 Axis. BioMed Research International 2021, pages 1-13.
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Christopher L. Moore, Alena V. Savenka & Alexei G. Basnakian. (2021) TUNEL Assay: A Powerful Tool for Kidney Injury Evaluation. International Journal of Molecular Sciences 22:1, pages 412.
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Qiuyuan Li, Minghui Cai, Jiao Wang, Qiang Gao, Xiaocheng Guo, Xiaotong Jia, Shanshan Xu & Hui Zhu. (2020) Decreased ovarian function and autophagy gene methylation in aging rats. Journal of Ovarian Research 13:1.
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Shixin Ding, Han Zhang, Zhenghao Sun, Yuli Han, Yan Li, Xianan Dong, Yanyan Yin, Weiping Li & Weizu Li. (2020) Ginsenoside Rg1 protects against aging-induced renal interstitial fibrosis due to inhibition of tubular epithelial cells endoplasmic reticulum stress in SAMP8 mice. Journal of Functional Foods 72, pages 104049.
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Yuan Xu, Yulin Niu, Haiyang Li & Guanghui Pan. (2020) Downregulation of lncRNA TUG1 attenuates inflammation and apoptosis of renal tubular epithelial cell induced by ischemia-reperfusion by sponging miR-449b-5p via targeting HMGB1 and MMP2. Inflammation 43:4, pages 1362-1374.
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Zhaohui Liu, Ji Zhang, Fang Zhang & Yulin Chang. (2020) Propofol post-conditioning lessens renal ischemia/reperfusion-induced acute lung injury associated with autophagy and apoptosis through MAPK signals in rats. Gene 741, pages 144562.
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Longhui Han, Minglian Zhang, Zanzhang Yang, Ke Diao, Xin Jia, Mingran Li & Genquan Tian. (2020) Huoxue-Tongluo-Lishui-Decoction is visual-protective against retinal ischemia-reperfusion injury. Biomedicine & Pharmacotherapy 125, pages 109998.
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Aged kidneys are refractory to autophagy activation in a rat model of renal ischemia-reperfusion injury

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Aged kidneys are refractory to autophagy activation in a rat model of renal ischemia-reperfusion injury

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