320
Views
21
CrossRef citations to date
0
Altmetric
Hypothesis

The cGAS/STING pathway: a sensor of senescence-associated DNA damage and trigger of inflammation in early age-related macular degeneration

, &
Pages 1277-1283 | Published online: 11 Jul 2019

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (1)

Yixing Tian, Zhaohua Bao, Yiming Ji, Xin Mei & Huilin Yang. (2020) Epigallocatechin-3-Gallate Protects H2O2-Induced Nucleus Pulposus Cell Apoptosis and Inflammation by Inhibiting cGAS/Sting/NLRP3 Activation. Drug Design, Development and Therapy 14, pages 2113-2122.
Read now

Articles from other publishers (20)

Min Heui Ha, Man S. Kim, Hyun‐Ju An, Min‐Ji Sung, Yu Ho Lee, Dong‐Ho Yang, Sang Hyun Jung, Jihyun Baek, Yueun Choi, Deanne M. Taylor, Yuanchao Zhang, So‐Young Lee & Hye Yun Jeong. (2023) PTEN ‐induced kinase 1 is associated with renal aging, via the cGAS ‐ STING pathway . Aging Cell.
Crossref
Zhuo WANG, MengMeng ZHAO & HaiPeng LIU. (2022) Progress in functional characterization of cGAS. SCIENTIA SINICA Vitae 53:2, pages 262-273.
Crossref
Janusz Blasiak, Piotr Sobczuk, Elzbieta Pawlowska & Kai Kaarniranta. (2022) Interplay between aging and other factors of the pathogenesis of age-related macular degeneration. Ageing Research Reviews 81, pages 101735.
Crossref
Yuhong Wang, Xiang Ma, Parthasarathy Muthuraman, Arun Raja, Aravindan Jayaraman, Konstantin Petrukhin, Christopher L. Cioffi, Jian-Xing Ma & Gennadiy Moiseyev. (2022) The novel visual cycle inhibitor (±)-RPE65-61 protects retinal photoreceptors from light-induced degeneration. PLOS ONE 17:10, pages e0269437.
Crossref
Haipeng Liu, Fei Wang, Yajuan Cao, Yifang Dang & Baoxue Ge. (2022) The multifaceted functions of cGAS. Journal of Molecular Cell Biology 14:5.
Crossref
Qingqiu Chen, Li Tang, Yi Zhang, Chengyu Wan, Xiuxian Yu, Yuman Dong, Xiaoting Chen, Xueling Wang, Ning Li, Guang Xin, Meixia Zhang, Zhen Chen, Hai Niu & Wen Huang. (2022) STING up-regulates VEGF expression in oxidative stress-induced senescence of retinal pigment epithelium via NF-κB/HIF-1α pathway. Life Sciences 293, pages 120089.
Crossref
Qi Pu, Xiao-Xiao Guo, Jing-Jie Hu, Ao-Ling Li, Gui-Gang Li & Xin-Yu Li. (2022) Nicotinamide mononucleotide increases cell viability and restores tight junctions in high-glucose-treated human corneal epithelial cells via the SIRT1/Nrf2/HO-1 pathway. Biomedicine & Pharmacotherapy 147, pages 112659.
Crossref
Yuanyuan Wang, Bin Wei, Danping Wang, Jingjing Wu, Jianhua Gao, Haiqing Zhong, Yang Sun, Qiang Xu, Wen Liu, Yanhong Gu & Wenjie Guo. (2022) DNA damage repair promotion in colonic epithelial cells by andrographolide downregulated cGAS‒STING pathway activation and contributed to the relief of CPT-11-induced intestinal mucositis. Acta Pharmaceutica Sinica B 12:1, pages 262-273.
Crossref
Ahmad Bereimipour, Leila Satarian & Sara Taleahmad. (2021) Investigation of Key Signaling Pathways Associating miR-204 and Common Retinopathies. BioMed Research International 2021, pages 1-13.
Crossref
Le Yu & Pengda Liu. (2021) Cytosolic DNA sensing by cGAS: regulation, function, and human diseases. Signal Transduction and Targeted Therapy 6:1.
Crossref
Kang Geng, Xiumei Ma, Zongzhe Jiang, Wei Huang, Chenlin Gao, Yueli Pu, Lifang Luo, Youhua Xu & Yong Xu. (2021) Innate Immunity in Diabetic Wound Healing: Focus on the Mastermind Hidden in Chronic Inflammatory. Frontiers in Pharmacology 12.
Crossref
Menghui Gao, Yuchen He, Haosheng Tang, Xiangyu Chen, Shuang Liu & Yongguang Tao. (2020) cGAS/STING: novel perspectives of the classic pathway. Molecular Biomedicine 1:1.
Crossref
Janusz Blasiak, Elzbieta Pawlowska, Anna Sobczuk, Joanna Szczepanska & Kai Kaarniranta. (2020) The Aging Stress Response and Its Implication for AMD Pathogenesis. International Journal of Molecular Sciences 21:22, pages 8840.
Crossref
E. N. Proshkina, I. A. Solovev, M. V. Shaposhnikov & A. A. Moskalev. (2021) Key Molecular Mechanisms of Aging, Biomarkers, and Potential Interventions. Molecular Biology 54:6, pages 777-811.
Crossref
Yingzhu Feng, Jiuhong Huang, Chuanhua Qu, Mengjun Huang, Zhencong Chen, Dianyong Tang, Zhigang Xu, Bochu Wang & Zhongzhu Chen. (2020) Future perspective: high-throughput construction of new ultrasensitive cytokine and virion liquid chips for high-throughput screening (HTS) of anti-inflammatory drugs or clinical diagnosis and treatment of inflammatory diseases. Analytical and Bioanalytical Chemistry 412:28, pages 7685-7699.
Crossref
Zhenxing Cheng, Simon T. Abrams, James Austin, Julien Toh, Susan Siyu Wang, Zhi Wang, Qian Yu, Weiping Yu, Cheng Hock Toh & Guozheng Wang. (2020) The Central Role and Possible Mechanisms of Bacterial DNAs in Sepsis Development. Mediators of Inflammation 2020, pages 1-11.
Crossref
Maarten P. Rozing, Jon A. Durhuus, Marie Krogh Nielsen, Yousif Subhi, Thomas BL. Kirkwood, Rudi GJ. Westendorp & Torben Lykke Sørensen. (2020) Age-related macular degeneration: A two-level model hypothesis. Progress in Retinal and Eye Research 76, pages 100825.
Crossref
Parameswaran G. Sreekumar, David R. Hinton & Ram Kannan. (2020) The Emerging Role of Senescence in Ocular Disease. Oxidative Medicine and Cellular Longevity 2020, pages 1-19.
Crossref
Janusz Blasiak. (2020) Senescence in the pathogenesis of age-related macular degeneration. Cellular and Molecular Life Sciences 77:5, pages 789-805.
Crossref
Lu Ye, Zhao Jiaqi, Wang Jianchao, Feng Zhaohui, Yao Liang & Zhang Xiaohui. (2020) Comparative efficacy and safety of anti-vascular endothelial growth factor regimens for neovascular age-related macular degeneration: systematic review and Bayesian network meta-analysis. Therapeutic Advances in Chronic Disease 11, pages 204062232095334.
Crossref