Advanced search
Publication Cover
Clinical Interventions in Aging Volume 14, 2019 - Issue
Submit an article Journal homepage
133
Views
13
CrossRef citations to date
0
Altmetric
Original Research

Long-term icariin treatment ameliorates cognitive deficits via CD4+ T cell-mediated immuno-inflammatory responses in APP/PS1 mice

Tianrui Zhu1 Department of Neurology, Jinan Central Hospital Affiliated to Shandong University, Jinan, Shandong 250013, People’s Republic of China
,
Feng Zhang1 Department of Neurology, Jinan Central Hospital Affiliated to Shandong University, Jinan, Shandong 250013, People’s Republic of China
,
Heng Li1 Department of Neurology, Jinan Central Hospital Affiliated to Shandong University, Jinan, Shandong 250013, People’s Republic of China
,
Yi He2 Department of Neurology, The Second Affiliated Hospital of Xi’an Medical University, Xi’an, Shaanxi 710021, People’s Republic of China
,
Guitao Zhang1 Department of Neurology, Jinan Central Hospital Affiliated to Shandong University, Jinan, Shandong 250013, People’s Republic of China
,
Nana Huang1 Department of Neurology, Jinan Central Hospital Affiliated to Shandong University, Jinan, Shandong 250013, People’s Republic of China
,
Mingming Guo3 Department of Breast Surgery, The Second Hospital of Shandong University, Jinan, Shandong 250033, People’s Republic of China
&
Xiaohong Li1 Department of Neurology, Jinan Central Hospital Affiliated to Shandong University, Jinan, Shandong 250013, People’s Republic of ChinaCorrespondence[email protected]
 show all
Pages 817-826 | Published online: 07 May 2019

Citations (13)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Meiyu Han, Lin Hu & Yang Chen. (2019) Rutaecarpine may improve neuronal injury, inhibits apoptosis, inflammation and oxidative stress by regulating the expression of ERK1/2 and Nrf2/HO-1 pathway in rats with cerebral ischemia-reperfusion injury. Drug Design, Development and Therapy 13, pages 2923-2931.
Read now

Articles from other publishers (12)

Yuqing Liu, Yejun Tan, Zheyu Zhang, Hongli Li, Min Yi, Zhen Zhang, Shan Hui & Weijun Peng. (2023) Neuroimmune mechanisms underlying Alzheimer’s disease: Insights into central and peripheral immune cell crosstalk. Ageing Research Reviews 84, pages 101831.
Crossref
Mingyao You, Ping Yuan, Liangqian Li & Hongbei Xu. (2022) HIF-1 signalling pathway was identified as a potential new pathway for Icariin’s treatment against Alzheimer’s disease based on preclinical evidence and bioinformatics. Frontiers in Pharmacology 13.
Crossref
Yu Chen, Fu Peng, Ziwei Xing, Junren Chen, Cheng Peng & Dan Li. (2022) Beneficial effects of natural flavonoids on neuroinflammation. Frontiers in Immunology 13.
Crossref
Zhuyu Luo, Jingcheng Dong & Jinfeng Wu. (2022) Impact of Icariin and its derivatives on inflammatory diseases and relevant signaling pathways. International Immunopharmacology 108, pages 108861.
Crossref
Zhangyang Bi, Wei Zhang & Xiaoyan Yan. (2022) Anti-inflammatory and immunoregulatory effects of icariin and icaritin. Biomedicine & Pharmacotherapy 151, pages 113180.
Crossref
Hongxia Yu, Jianhong Shi, Yiyou Lin, Yehui Zhang, Qihang Luo, Suo Huang, Sichen Wang, Jiale Wei, Junhao Huang, Changyu Li & Liting Ji. (2022) Icariin Ameliorates Alzheimer’s Disease Pathology by Alleviating Myelin Injury in 3 × Tg-AD Mice. Neurochemical Research 47:4, pages 1049-1059.
Crossref
Baolin Su, Dejin Cheng, Gangyi Chen, Shu Zhang, Liangliang Wang, Xingbo Wu & Shuifu Tang. (2022) Icariin Attenuation of Diabetic Kidney Disease Through Inhibition of Endoplasmic Reticulum Stress via G Protein-Coupled Estrogen Receptors. Journal of Biomedical Nanotechnology 18:2, pages 488-497.
Crossref
Rui Zheng, Yang-mei Huang & Qiang Zhou. (2021) Xueshuantong Improves Functions of Lymphatic Ducts and Modulates Inflammatory Responses in Alzheimer’s Disease Mice. Frontiers in Pharmacology 12.
Crossref
Yating Wu, Jianbo Zhu, Haifeng Liu & Hailiang Liu. (2021) Licochalcone A improves the cognitive ability of mice by regulating T- and B-cell proliferation. Aging 13:6, pages 8895-8915.
Crossref
Katriona L. Hole & Robert J. Williams. (2021) Flavonoids as an Intervention for Alzheimer’s Disease: Progress and Hurdles Towards Defining a Mechanism of Action1. Brain Plasticity 6:2, pages 167-192.
Crossref
Xuexia Li, Zhijun He, Chao Wang, Yanjun Liu, Zhifu Shan, Lei Zhang, Qingqing Shi, Caiping Yue, Yitong Lin, Yun Liu, Jiazuan Ni & Xiubo Du. (2020) Effect of Herbal Medicinal Compounds on Alzheimer’s Disease Pathology in APP/PS1 Transgenic Mouse Model. Natural Product Communications 15:8, pages 1934578X2094898.
Crossref
Tuo Liang, Zhong-Ming Qian, Ming-Dao Mu, Wing-Ho Yung & Ya Ke. (2020) Brain Hepcidin Suppresses Major Pathologies in Experimental Parkinsonism. iScience 23:7, pages 101284.
Crossref

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.