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Clinical Interventions in Aging Volume 15, 2020 - Issue
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Review

COVID-19: The Influence of ACE Genotype and ACE-I and ARBs on the Course of SARS-CoV-2 Infection in Elderly Patients

Jerzy Sieńko1 Department of General Surgery and Transplantology, Pomeranian Medical University in Szczecin, Szczecin, PolandORCID Iconhttps://orcid.org/0000-0001-8141-7489
ORCID Icon,
Maciej Kotowski1 Department of General Surgery and Transplantology, Pomeranian Medical University in Szczecin, Szczecin, PolandORCID Iconhttps://orcid.org/0000-0003-4870-0156
ORCID Icon,
Anna Bogacz2 Department of Pharmacology and Phytochemistry, Institute of Natural Fibers and Medicinal Plants, Poznan, PolandORCID Iconhttps://orcid.org/0000-0001-5455-8315
ORCID Icon,
Kacper Lechowicz3 Department of Anaesthesiology, Intensive Therapy and Acute Intoxications, Pomeranian Medical University in Szczecin, Szczecin, PolandORCID Iconhttps://orcid.org/0000-0002-0807-8510
ORCID Icon,
Sylwester Drożdżal4 Department of Pharmacokinetics and Monitored Therapy, Pomeranian Medical University in Szczecin, Szczecin, Poland
,
Jakub Rosik5 Department of Physiology, Pomeranian Medical University in Szczecin, Szczecin, PolandORCID Iconhttps://orcid.org/0000-0001-7377-4566
ORCID Icon,
Marek Sietnicki6 Department of Civil Engineering and Architecture, West Pomeranian University of Technology in Szczecin, Szczecin, PolandORCID Iconhttps://orcid.org/0000-0003-4190-8851
ORCID Icon,
Magdalena Sieńko7 Department of Pediatrics, Endocrinology, Diabetology, Metabolic Diseases and Cardiology, Pomeranian Medical University in Szczecin, Szczecin, Poland
&
Katarzyna Kotfis3 Department of Anaesthesiology, Intensive Therapy and Acute Intoxications, Pomeranian Medical University in Szczecin, Szczecin, PolandCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-8430-1369
ORCID Icon show all
Pages 1231-1240 | Published online: 21 Jul 2020

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William Toppen, Peter Yan, Daniela Markovic, Carolyn M Shover, Russell G Buhr, Jennifer A Fulcher, Donald P Tashkin & Igor Barjaktarevic. (2022) Chronic Obstructive Pulmonary Disease is Not Associated with In-Hospital Mortality in COVID-19: An Observational Cohort Analysis. International Journal of Chronic Obstructive Pulmonary Disease 17, pages 3111-3121.
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Romany H. Thabet, Noor A. Massadeh, Omar B. Badarna & Omar M. Al-Momani. (2023) Highlights on molecular targets in the management of COVID-19: Possible role of pharmacogenomics. Journal of International Medical Research 51:1, pages 030006052311537.
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Siyeon Suh, Sol Lee, Ho Gym, Sanghyuk Yoon, Seunghwan Park, Jihi Cha, Do-Hyung Kwon, YunSu Yang & Sun Ha Jee. (2022) A systematic review on papers that study on Single Nucleotide Polymorphism that affects coronavirus 2019 severity. BMC Infectious Diseases 22:1.
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Jerzy Sienko, Izabela Marczak, Maciej Kotowski, Anna Bogacz, Karol Tejchman, Magdalena Sienko & Katarzyna Kotfis. (2022) Association of ACE2 Gene Variants with the Severity of COVID-19 Disease—A Prospective Observational Study. International Journal of Environmental Research and Public Health 19:19, pages 12622.
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Gonzalo Villapalos-García, Pablo Zubiaur, Rebeca Rivas-Durán, Pilar Campos-Norte, Cristina Arévalo-Román, Marta Fernández-Rico, Lucio García-Fraile Fraile, Paula Fernández-Campos, Paula Soria-Chacartegui, Sara Fernández de Córdoba-Oñate, Pablo Delgado-Wicke, Elena Fernández-Ruiz, Isidoro González-Álvaro, Jesús Sanz, Francisco Abad-Santos & Ignacio de los Santos. (2022) Transmembrane protease serine 2 ( TMPRSS2 ) rs75603675, comorbidity, and sex are the primary predictors of COVID-19 severity . Life Science Alliance 5:10, pages e202201396.
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Wacharapol Saengsiwaritt, Jiraphun Jittikoon, Usa Chaikledkaew & Wanvisa Udomsinprasert. (2022) Genetic polymorphisms of ACE1 , ACE2 , and TMPRSS2 associated with COVID‐19 severity: A systematic review with meta‐analysis . Reviews in Medical Virology 32:4.
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Anna Gorący, Jakub Rosik, Bartosz Szostak, Łukasz Ustianowski, Klaudia Ustianowska & Jarosław Gorący. (2022) Human Cell Organelles in SARS-CoV-2 Infection: An Up-to-Date Overview. Viruses 14:5, pages 1092.
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Abolfazl Adli, Mandana Rahimi, Reza Khodaie, Niloofar Hashemzaei & Sayed M. Hosseini. (2022) Role of genetic variants and host polymorphisms on COVID‐19: From viral entrance mechanisms to immunological reactions. Journal of Medical Virology 94:5, pages 1846-1865.
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Erwan Sallard, Frank Schult, Carolin Baehren, Eleni Buedding, Olivier Mboma, Parviz Ahmad-Nejad, Beniam Ghebremedhin, Anja Ehrhardt, Stefan Wirth & Malik Aydin. (2022) Viral Infection and Respiratory Exacerbation in Children: Results from a Local German Pediatric Exacerbation Cohort. Viruses 14:3, pages 491.
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Angélica Regina Cappellari, Julia Brandt de Souza, Daniele Rubert Nogueira-Librelotto, Jéssica Dotto de Lara, Jéssica Carla Martins Couto, Júlia Leão Batista Simões, Margarete Dulce Bagatini, Carlos Fernando Mello & Micheli Mainardi Pillat. 2022. Frontiers of COVID-19. Frontiers of COVID-19 31 48 .
Halim Saad, Karna Jabotian, Carine Sakr, Rami Mahfouz, Imad Bou Akl & Nathalie K. Zgheib. (2021) The Role of Angiotensin Converting Enzyme 1 Insertion/Deletion Genetic Polymorphism in the Risk and Severity of COVID-19 Infection. Frontiers in Medicine 8.
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Hao Deng, Xue Yan & Lamei Yuan. (2021) Human genetic basis of coronavirus disease 2019. Signal Transduction and Targeted Therapy 6:1.
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Mariana Alves, Marília Andreia Fernandes, Gülistan Bahat, Athanase Benetos, Hugo Clemente, Tomasz Grodzicki, Manuel Martínez-Sellés, Francesco Mattace-Raso, Chakravarthi Rajkumar, Andrea Ungar, Nikos Werner, Timo E. Strandberg, Grodzicki & Strandberg. (2021) Protecting older patients with cardiovascular diseases from COVID-19 complications using current medications. European Geriatric Medicine 12:4, pages 725-739.
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Ait Boujmia Oum Kaltoum. (2021) Mutations and polymorphisms in genes involved in the infections by covid 19: a review. Gene Reports 23, pages 101062.
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Thirumalaisamy P. Velavan, Christian G. Meyer, Meral Esen, Peter G. Kremsner & Francine Ntoumi. (2021) COVID-19 and syndemic challenges in ‘Battling the Big Three’: HIV, TB and malaria. International Journal of Infectious Diseases 106, pages 29-32.
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Deborah Traversi, Alessandra Pulliero, Alberto Izzotti, Elena Franchitti, Licia Iacoviello, Francesco Gianfagna, Alessandro Gialluisi, Benedetta Izzi, Antonella Agodi, Martina Barchitta, Giovanna Elisa Calabrò, Ilda Hoxhaj, Michele Sassano, Luca Gino Sbrogiò, Annamaria Del Sole, Francesco Marchiori, Erica Pitini, Giuseppe Migliara, Carolina Marzuillo, Corrado De Vito, Manuela Tamburro, Michela Lucia Sammarco, Giancarlo Ripabelli, Paolo Villari & Stefania Boccia. (2021) Precision Medicine and Public Health: New Challenges for Effective and Sustainable Health. Journal of Personalized Medicine 11:2, pages 135.
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Ehab S. EL Desoky. (2021) COVID-19 and Renin Angiotensin Aldosterone System: A Pharmacogenomic View. American Journal of Therapeutics 28:1, pages e136-e139.
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Mohadeseh Haji Abdolvahab, Shima Moradi-kalbolandi, Mohammad Zarei, Deepanwita Bose, Keivan Majidzadeh-A & Leila Farahmand. (2021) Potential role of interferons in treating COVID-19 patients. International Immunopharmacology 90, pages 107171.
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Dongqiong Xiao, Xihong Li, Xiaojuan Su, Dezhi Mu & Yi Qu. (2021) Could SARS-CoV-2-induced lung injury be attenuated by vitamin D?. International Journal of Infectious Diseases 102, pages 196-202.
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Min Cheol Chang & Donghwi Park. (2020) Incidence of Post-Traumatic Stress Disorder after Coronavirus Disease. Healthcare 8:4, pages 373.
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Ya Yang, Yalei Zhao, Fen Zhang, Lingjian Zhang & Lanjuan Li. (2020) COVID-19 in Elderly Adults: Clinical Features, Molecular Mechanisms, and Proposed Strategies. Aging and disease 11:6, pages 1481.
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