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Clinical Interventions in Aging Volume 9, 2014 - Issue
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Original Research

Long-term safety and tolerability of saxagliptin add-on therapy in older patients (aged ≥65 years) with type 2 diabetes

Nayyar Iqbal1 Bristol-Myers Squibb, Princeton, NJ, USACorrespondence[email protected]
,
Elsie Allen1 Bristol-Myers Squibb, Princeton, NJ, USA
&
Peter Öhman2 AstraZeneca, Wilmington, DE, USA
Pages 1479-1487 | Published online: 04 Sep 2014

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Read on this site (3)

André J. Scheen. (2021) Careful use to minimize adverse events of oral antidiabetic medications in the elderly. Expert Opinion on Pharmacotherapy 22:16, pages 2149-2165.
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Simona Cernea, Avivit Cahn & Itamar Raz. (2016) Saxagliptin for the treatment of diabetes - a focus on safety. Expert Opinion on Drug Safety 15:5, pages 697-707.
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André J Scheen. (2015) Safety of dipeptidyl peptidase-4 inhibitors for treating type 2 diabetes. Expert Opinion on Drug Safety 14:4, pages 505-524.
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Articles from other publishers (14)

André J. Scheen. (2021) Efficacy / safety balance of DPP-4 inhibitors versus SGLT2 inhibitors in elderly patients with type 2 diabetes. Diabetes & Metabolism 47:6, pages 101275.
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Kasper S Madsen, Pernille Kähler, Lise Katrine Aronsen Kähler, Sten Madsbad, Filip Gnesin, Maria-Inti Metzendorf, Bernd Richter & Bianca Hemmingsen. (2019) Metformin and second- or third-generation sulphonylurea combination therapy for adults with type 2 diabetes mellitus. Cochrane Database of Systematic Reviews.
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Willy Marcos Valencia, Diana Botros, Maria Vera-Nunez & Stuti Dang. (2018) Diabetes Treatment in the Elderly: Incorporating Geriatrics, Technology, and Functional Medicine. Current Diabetes Reports 18:10.
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R. Gómez-Huelgas, F. Gómez Peralta, L. Rodríguez Mañas, F. Formiga, M. Puig Domingo, J.J. Mediavilla Bravo, C. Miranda & J. Ena. (2018) Tratamiento de la diabetes mellitus tipo 2 en el paciente anciano. Revista Española de Geriatría y Gerontología 53:2, pages 89-99.
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R. Gómez-Huelgas, F. Gómez Peralta, L. Rodríguez Mañas, F. Formiga, M. Puig Domingo, J.J. Mediavilla Bravo, C. Miranda & J. Ena. (2018) Treatment of type 2 diabetes mellitus in elderly patients. Revista Clínica Española (English Edition) 218:2, pages 74-88.
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R. Gómez-Huelgas, F. Gómez Peralta, L. Rodríguez Mañas, F. Formiga, M. Puig Domingo, J.J. Mediavilla Bravo, C. Miranda & J. Ena. (2018) Tratamiento de la diabetes mellitus tipo 2 en el paciente anciano. Revista Clínica Española 218:2, pages 74-88.
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Mikaela Sjöstrand, Cheryl Wei, William Cook, Kristina Johnsson, Pia S. Pollack, Christina Stahre & Boaz Hirshberg. (2017) Assessment of Saxagliptin Efficacy: Meta-Analysis of 14 Phase 2 and 3 Clinical Trials. Diabetes Therapy 8:3, pages 587-599.
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David W. Boulton. (2016) Clinical Pharmacokinetics and Pharmacodynamics of Saxagliptin, a Dipeptidyl Peptidase-4 Inhibitor. Clinical Pharmacokinetics 56:1, pages 11-24.
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Shira Perl, William Cook, Cheryl Wei, Peter Ohman & Boaz Hirshberg. (2016) Effects of Glimepiride versus Saxagliptin on β-Cell Function and Hypoglycemia: A Post Hoc Analysis in Older Patients with Type 2 Diabetes Inadequately Controlled with Metformin. Clinical Therapeutics 38:12, pages 2578-2588.
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Weiqiong Gu, Li. Liang, Shengxiang Wang, Yunzhi Wang, Yanxiang Wu, Jian Tian, Gangyi Yang, Chunli Piao, Yuzhong Li, Jianmei Yin, Xiaoping Xin, Xingrong Tan, Guang Ning & Weiqing Wang. (2016) Efficacy and safety of saxagliptin monotherapy or added to metformin in Chinese patients with type 2 diabetes mellitus: results from the 24-week, post-marketing SUNSHINE study. Journal of Diabetes 8:6, pages 809-815.
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J.-F. Blicklé. (2016) Quelle place pour les nouveaux antidiabétiques dans la prise en charge du diabète du sujet âgé ?. Médecine des Maladies Métaboliques 10:6, pages 574-580.
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Francesc Formiga, Ricardo Gómez-Huelgas & Leocadio Rodríguez Mañas. (2016) Características diferenciales de la diabetes mellitus tipo 2 en el paciente anciano. Papel de los inhibidores de la dipeptidil peptidasa 4. Revista Española de Geriatría y Gerontología 51:1, pages 44-51.
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Sohita Dhillon. (2015) Saxagliptin: A Review in Type 2 Diabetes. Drugs 75:15, pages 1783-1796.
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Tatsuya Machida, Takaaki Tomofuji, Daisuke Ekuni, Takayuki Maruyama, Toshiki Yoneda, Yuya Kawabata, Hirofumi Mizuno, Hisataka Miyai, Muneyoshi Kunitomo & Manabu Morita. (2015) MicroRNAs in Salivary Exosome as Potential Biomarkers of Aging. International Journal of Molecular Sciences 16:9, pages 21294-21309.
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