Mécano-Stimulation™ of the skin improves sagging score and induces beneficial functional modification of the fibroblasts: clinical, biological, and histological evaluations

Philippe Humbert1 Research and Studies Center on the Integument (CERT), Department of Dermatology, Clinical Investigation Center (CIC 1431), Besançon University Hospital, Besançon, France;2 INSERM UMR1098, FED4234 IBCT, University of Franche-Comté, Besançon, FranceCorrespondence[email protected]

Ferial Fanian1 Research and Studies Center on the Integument (CERT), Department of Dermatology, Clinical Investigation Center (CIC 1431), Besançon University Hospital, Besançon, France;2 INSERM UMR1098, FED4234 IBCT, University of Franche-Comté, Besançon, France

Thomas Lihoreau1 Research and Studies Center on the Integument (CERT), Department of Dermatology, Clinical Investigation Center (CIC 1431), Besançon University Hospital, Besançon, France;2 INSERM UMR1098, FED4234 IBCT, University of Franche-Comté, Besançon, France

Adeline Jeudy1 Research and Studies Center on the Integument (CERT), Department of Dermatology, Clinical Investigation Center (CIC 1431), Besançon University Hospital, Besançon, France;2 INSERM UMR1098, FED4234 IBCT, University of Franche-Comté, Besançon, France

Ahmed Elkhyat1 Research and Studies Center on the Integument (CERT), Department of Dermatology, Clinical Investigation Center (CIC 1431), Besançon University Hospital, Besançon, France;2 INSERM UMR1098, FED4234 IBCT, University of Franche-Comté, Besançon, France

Sophie Robin3 SARL BIOEXIGENCE, Besançon, France

Carol Courderot-Masuyer3 SARL BIOEXIGENCE, Besançon, France

Hélène Tauzin3 SARL BIOEXIGENCE, Besançon, France

Christine Lafforgue1 Research and Studies Center on the Integument (CERT), Department of Dermatology, Clinical Investigation Center (CIC 1431), Besançon University Hospital, Besançon, France;2 INSERM UMR1098, FED4234 IBCT, University of Franche-Comté, Besançon, France;4 Dermopharmacology and Cosmetology Unit, University of Paris Sud, France

Marek Haftek5 University of Lyon 1, EA4169, Experimental, clinical and therapeutic aspects of the skin barrier function, INSERM US7 – CNRS UMS3453, Lyon, France

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Mécano-Stimulation™ of the skin improves sagging score and induces beneficial functional modification of the fibroblasts: clinical, biological, and histological evaluations

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Mécano-Stimulation™ of the skin improves sagging score and induces beneficial functional modification of the fibroblasts: clinical, biological, and histological evaluations

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