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Clinical Epidemiology Volume 13, 2021 - Issue
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Original Research

Long-Term Risk of Skin Cancer and Lymphoma in Users of Topical Tacrolimus and Pimecrolimus: Final Results from the Extension of the Cohort Study Protopic Joint European Longitudinal Lymphoma and Skin Cancer Evaluation (JOELLE)

Alejandro Arana1 Department of Epidemiology, RTI Health Solutions, Barcelona, 08028, SpainCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-1593-3124View further author information
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Anton Pottegård2 Clinical Pharmacology, Pharmacy and Environmental Medicine, Institute of Public Health, University of Southern Denmark, Odense C, 5000, DenmarkORCID Iconhttps://orcid.org/0000-0001-9314-5679View further author information
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Josephina G Kuiper3 The PHARMO Institute, Utrecht, 3528 AE, the NetherlandsORCID Iconhttps://orcid.org/0000-0002-4487-3546View further author information
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Helen Booth4 Clinical Practice Research Datalink (CPRD), The Medicines and Healthcare Products Regulatory Agency, London, E14 4PU, UKView further author information
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Johan Reutfors5 Centre for Pharmacoepidemiology, Karolinska Institutet, Solna, 171 76, Stockholm, SwedenORCID Iconhttps://orcid.org/0000-0003-1372-4262View further author information
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Brian Calingaert6 Department of Epidemiology, RTI Health Solutions, Research Triangle Park, NC, 27709-2194, USAORCID Iconhttps://orcid.org/0000-0001-8177-6326View further author information
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Lars Christian Lund2 Clinical Pharmacology, Pharmacy and Environmental Medicine, Institute of Public Health, University of Southern Denmark, Odense C, 5000, DenmarkView further author information
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Elizabeth Crellin4 Clinical Practice Research Datalink (CPRD), The Medicines and Healthcare Products Regulatory Agency, London, E14 4PU, UKORCID Iconhttps://orcid.org/0000-0001-8774-224XView further author information
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Marcus Schmitt-Egenolf5 Centre for Pharmacoepidemiology, Karolinska Institutet, Solna, 171 76, Stockholm, Sweden;7 Department of Public Health and Clinical Medicine, Umeå University, Umeå, 901 87, SwedenORCID Iconhttps://orcid.org/0000-0002-3858-8474View further author information
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James A Kaye8 Department of Epidemiology, RTI Health Solutions, Waltham, MA, 02451-1623, USAORCID Iconhttps://orcid.org/0000-0002-9357-4227View further author information
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Karin Gembert5 Centre for Pharmacoepidemiology, Karolinska Institutet, Solna, 171 76, Stockholm, SwedenView further author information
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Kenneth J Rothman8 Department of Epidemiology, RTI Health Solutions, Waltham, MA, 02451-1623, USAView further author information
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Helle Kieler5 Centre for Pharmacoepidemiology, Karolinska Institutet, Solna, 171 76, Stockholm, SwedenView further author information
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Daniel Dedman4 Clinical Practice Research Datalink (CPRD), The Medicines and Healthcare Products Regulatory Agency, London, E14 4PU, UKORCID Iconhttps://orcid.org/0000-0002-3699-5391View further author information
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Eline Houben3 The PHARMO Institute, Utrecht, 3528 AE, the NetherlandsORCID Iconhttps://orcid.org/0000-0002-9173-3335View further author information
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Lia Gutiérrez1 Department of Epidemiology, RTI Health Solutions, Barcelona, 08028, SpainORCID Iconhttps://orcid.org/0000-0001-6280-1119View further author information
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Jesper Hallas2 Clinical Pharmacology, Pharmacy and Environmental Medicine, Institute of Public Health, University of Southern Denmark, Odense C, 5000, DenmarkORCID Iconhttps://orcid.org/0000-0002-8097-8708View further author information
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Susana Perez-Gutthann1 Department of Epidemiology, RTI Health Solutions, Barcelona, 08028, SpainORCID Iconhttps://orcid.org/0000-0001-5798-3691View further author information
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Pages 1141-1153 | Published online: 29 Dec 2021

Citations (6)

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Xia Dou, Lingling Liu, Xuejun Zhu, Weijing Wen, Chunya Ni, Yi Zhao, Zhixin He, Hongchun Li, Qiuning Sun, Qinping Yang, Xinfen Sun & Yifeng Guo. (2023) Safety and efficacy of Pimecrolimus in atopic dermatitis among Chinese infants: a sub-group analysis of a five-year open-label study. Journal of Dermatological Treatment 34:1.
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Articles from other publishers (5)

Sharon Zhao, Austin Hwang, Corinne Miller & Peter Lio. (2023) Safety of topical medications in the management of paediatric atopic dermatitis: An updated systematic review. British Journal of Clinical Pharmacology 89:7, pages 2039-2065.
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David P. Skoner, Alexandra K. Golant, Allison E. Norton & David R. Stukus. (2022) Is This Medication Safe for My Child? How to Discuss Safety of Commonly Used Medications With Parents. The Journal of Allergy and Clinical Immunology: In Practice 10:12, pages 3064-3072.
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Yiheng Liang, Guangrong Liu, Lingna Xie, Kewen Su, Xia Chang, Yani Xu, Junsong Chen, Zhenyuan Zhu, Kaiye Yang, Huixiong Chen & Zhiyun Du. (2022) Dendrobium candidum polysaccharide reduce atopic dermatitis symptoms and modulate gut microbiota in DNFB-induced AD-like mice. Frontiers in Physiology 13.
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Badar Uddin Umar, Sayeeda Rahman, Siddhartha Dutta, Tariqul Islam, Nadia Nusrat, Kona Chowdhury, Wan Farizatul Shima Binti Wan Ahmad Fakuradzi & Mainul Haque. (2022) Management of Atopic Dermatitis: The Role of Tacrolimus. Cureus.
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Pablo L Ortiz-Romero, Lidia Maroñas Jiménez, Cristina Muniesa, Teresa Estrach, Octavio Servitje, Ricardo Fernández-de-Misa, Fernando Gallardo, Onofre Sanmartín, Erica Riveiro-Falkenbach, Nuria García-Díaz, Rosa Vega, David Lora, Concepción Postigo, Blanca Jiménez, Margarita Sánchez-Beato, José Pedro Vaqué, José Luis Rodríguez Peralto, Agustín Gómez de la Cámara, Javier de la Cruz & Miguel Ángel Piris Pinilla. (2022) Activity and safety of topical pimecrolimus in patients with early stage mycosis fungoides (PimTo-MF): a single-arm, multicentre, phase 2 trial. The Lancet Haematology 9:6, pages e425-e433.
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