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Original Research

NLRP6, decreased in gastric cancer, suppresses tumorigenicity of gastric cancer cells

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Pages 6431-6444 | Published online: 27 Nov 2018

Keep up to date with the latest research on this topic with citation updates for this article.

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Xiaoyu Qian, Jian Tang, Yongquan Chu, Ziqiang Chen, Liang Chen, Chao Shen & Lin Li. (2021) A Novel Pyroptosis-Related Gene Signature for Prognostic Prediction of Head and Neck Squamous Cell Carcinoma. International Journal of General Medicine 14, pages 7669-7679.
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Yangmei Zhang, Xichang Zhou, ManMan Zhang, Long Cheng, Youwei Zhang & Xiang Wang. (2019) ZBTB20 promotes cell migration and invasion of gastric cancer by inhibiting IκBα to induce NF-κB activation. Artificial Cells, Nanomedicine, and Biotechnology 47:1, pages 3862-3872.
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Articles from other publishers (22)

Yujun Guo, Wenjun Lu, Ze’nan Zhang, Hengchen Liu, Aodan Zhang, Tingting Zhang, Yang Wu, Xiangqi Li, Shulong Yang, Qingbo Cui & Zhaozhu Li. (2024) A novel pyroptosis-related gene signature exhibits distinct immune cells infiltration landscape in Wilms’ tumor. BMC Pediatrics 24:1.
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Qi He, Changchang Meng, Mengjie Jia, Junyi Tan, Keli Huang, Hui Gan, Lingyu Li & Jing Zhao. (2024) NLRP6 deficiency inhibits neuroinflammation and ameliorates brain injury in ischemic stroke by blocking NLRs inflammasomes activation through proteasomal degradation of pro-caspase-1. Neurobiology of Disease 192, pages 106434.
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Hongjin Wang, Nian Wang, Ze Tang, Qiuyu Liu, Shiyu Nie & Wu Tao. (2023) An 8-gene predicting survival model of hepatocellular carcinoma (HCC) related to pyroptosis and cuproptosis. Hereditas 160:1.
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Liangzheng Chang, Yuying Tian, Lei Xu, Qiuyao Hao, Lingyu Song, Yinying Lu & Yunhuan Zhen. (2023) Spotlight on NLRP6 and Tumor Research Situation: A Potential Cancer Participant. Journal of Immunology Research 2023, pages 1-12.
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Ke-qian Chen, Bo-yi Ke, Lu Cheng, Xiao-qing Yu, Zong-bao Wang & Shu-zhi Wang. (2023) Research and progress of inflammasomes in nonalcoholic fatty liver disease. International Immunopharmacology 118, pages 110013.
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Chuanfeng Tang, Qiaona Wang, Jingyan Shen, Congying Wang, Hong Ding, Shiyu Wen, Fan Yang, Ruiqing Jiao, Xingxin Wu, Jianmei Li & Lingdong Kong. (2023) Neuron stem cell NLRP6 sustains hippocampal neurogenesis to resist stress-induced depression. Acta Pharmaceutica Sinica B 13:5, pages 2017-2038.
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Hongyu Wang, Bo Zhang, Yanan Shang, Fei Chen, Yumei Fan & Ke Tan. (2023) A novel risk score model based on pyroptosis-related genes for predicting survival and immunogenic landscape in hepatocellular carcinoma. Aging.
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Guanghao Wu, Biying Chen, Junjie Jiang, Yiran Chen, Yanyan Chen & Haiyong Wang. (2022) Identification of a pyroptosis‐based model for predicting clinical outcomes from immunotherapy in patients with metastatic melanoma. Cancer Medicine 12:4, pages 4921-4937.
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Zhanzhan Li, Lin Shen, Yanyan Li, Liangfang Shen & Na Li. (2022) Identification of pyroptosis‐related gene prognostic signature in head and neck squamous cell carcinoma. Cancer Medicine 11:24, pages 5129-5144.
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Xinrui Rao, Xiaoshu Zhou, Geng Wang, Xiaohua Jie, Biyuan Xing, Yingzhuo Xu, Yunshang Chen, Jun Li, Kuikui Zhu, Zilong Wu, Gang Wu, Chuangyan Wu & Rui Zhou. (2022) NLRP6 is required for cancer-derived exosome-modified macrophage M2 polarization and promotes metastasis in small cell lung cancer. Cell Death & Disease 13:10.
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Runzhi Li, Yang Zan, Kaiwen Sui & Shu Zhu. (2022) The latest breakthrough on NLRP6 inflammasome. Precision Clinical Medicine 5:3.
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Tianhao Zhou, Tao Wang, Kai Zeng, Rui Qin, Yuan Jin, Pang Chen & Gaoda Ju. (2022) A nomogram based on a three pyroptosis gene model and clinical parameters for predicting prognosis of hepatocellular carcinoma. Gene 819, pages 146243.
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Feng Zhang, Yan Deng, Dong Wang & Shuai Wang. (2022) Construction and validation of a pyroptosis-related gene signature associated with the tumor microenvironment in uveal melanoma. Scientific Reports 12:1.
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Shuqiao Zhang, Xinyu Li, Xiang Zhang, Shijun Zhang, Chunzhi Tang & Weihong Kuang. (2022) The Pyroptosis-Related Gene Signature Predicts the Prognosis of Hepatocellular Carcinoma. Frontiers in Molecular Biosciences 8.
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Ruby Dawson & Brendan J. Jenkins. 2021. Research and Clinical Applications of Targeting Gastric Neoplasms. Research and Clinical Applications of Targeting Gastric Neoplasms 43 90 .
Xinyue Wang, Xuewen Wu, Qingqing Wang, Yue Zhang, Chunmei Wang & Jinlian Chen. (2020) NLRP6 suppresses gastric cancer growth via GRP78 ubiquitination. Experimental Cell Research 395:1, pages 112177.
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Yiming Zhao, Lingling Chen, Zongshan Shen, Junda Li, Shuheng Huang, Runfu Wang, Zhengmei Lin & Zhi Song. (2020) Expression of nucleotide-binding oligomerization domain-like receptor family pyrin domain containing 6 in human dental pulp tissues and cells. Archives of Oral Biology 117, pages 104794.
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Xiaoyu Ji, Lili Li, Panpan Lu, Xin Li, Dean Tian & Mei Liu. (2020) NLRP6 exerts a protective role via NF-kB with involvement of CCL20 in a mouse model of alcoholic hepatitis. Biochemical and Biophysical Research Communications 528:3, pages 485-492.
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Silke Neumann, Estelle M. Peyroux, Matt J. Woodall, Nick J. Shields, Sarah L. Young & Sharon T. Pattison. 2020. Current Cancer Treatment. Current Cancer Treatment.
Yunlei Bai & Sheng Li. (2019) Long noncoding RNA OIP5‐AS1 aggravates cell proliferation, migration in gastric cancer by epigenetically silencing NLRP6 expression via binding EZH2. Journal of Cellular Biochemistry 121:1, pages 353-362.
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Xinyu Cao & Jia Xu. (2019) Insights into inflammasome and its research advances in cancer. Tumori Journal 105:6, pages 456-464.
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Min Gao, Peng Zhang, Li Huang, Hua Shao, Shuyin Duan, Chunyang Li, Qiao Zhang, Wei Wang, Yongjun Wu, Jing Wang, Hong Liu & Feifei Feng. (2019) Is NLRP3 or NLRP6 inflammasome activation associated with inflammation-related lung tumorigenesis induced by benzo(a)pyrene and lipopolysaccharide?. Ecotoxicology and Environmental Safety 185, pages 109687.
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