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Cancer Management and Research Volume 11, 2019 - Issue
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Original Research

DCZ0814 induces apoptosis and G0/G1 phase cell cycle arrest in myeloma by dual inhibition of mTORC1/2

Yuanyuan Kong1 Department of Hematology, Shanghai Tenth People’s Hospital, Tongji University Cancer Center, Tongji University School of Medicine, Shanghai 200072, People’s Republic of China
,
Bo Li2 CAS Key Laboratory of Receptor Research, Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, People’s Republic of China
,
Shuaikang Chang1 Department of Hematology, Shanghai Tenth People’s Hospital, Tongji University Cancer Center, Tongji University School of Medicine, Shanghai 200072, People’s Republic of China
,
Lu Gao1 Department of Hematology, Shanghai Tenth People’s Hospital, Tongji University Cancer Center, Tongji University School of Medicine, Shanghai 200072, People’s Republic of China
,
Zhijian Xu2 CAS Key Laboratory of Receptor Research, Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, People’s Republic of China
,
Wan He1 Department of Hematology, Shanghai Tenth People’s Hospital, Tongji University Cancer Center, Tongji University School of Medicine, Shanghai 200072, People’s Republic of China
,
Guang Yang1 Department of Hematology, Shanghai Tenth People’s Hospital, Tongji University Cancer Center, Tongji University School of Medicine, Shanghai 200072, People’s Republic of China
,
Bingqian Xie1 Department of Hematology, Shanghai Tenth People’s Hospital, Tongji University Cancer Center, Tongji University School of Medicine, Shanghai 200072, People’s Republic of China
,
Gege Chen1 Department of Hematology, Shanghai Tenth People’s Hospital, Tongji University Cancer Center, Tongji University School of Medicine, Shanghai 200072, People’s Republic of China
,
Liangning Hu1 Department of Hematology, Shanghai Tenth People’s Hospital, Tongji University Cancer Center, Tongji University School of Medicine, Shanghai 200072, People’s Republic of China
,
Kang Lu1 Department of Hematology, Shanghai Tenth People’s Hospital, Tongji University Cancer Center, Tongji University School of Medicine, Shanghai 200072, People’s Republic of China
,
Yingcong Wang1 Department of Hematology, Shanghai Tenth People’s Hospital, Tongji University Cancer Center, Tongji University School of Medicine, Shanghai 200072, People’s Republic of China
,
Xiaosong Wu1 Department of Hematology, Shanghai Tenth People’s Hospital, Tongji University Cancer Center, Tongji University School of Medicine, Shanghai 200072, People’s Republic of China
,
Weiliang Zhu2 CAS Key Laboratory of Receptor Research, Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, People’s Republic of ChinaCorrespondence[email protected]
&
Jumei Shi1 Department of Hematology, Shanghai Tenth People’s Hospital, Tongji University Cancer Center, Tongji University School of Medicine, Shanghai 200072, People’s Republic of ChinaCorrespondence[email protected]
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Pages 4797-4808 | Published online: 27 May 2019

Citations (2)

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Read on this site (1)

Yaqi Xu, Xiaoli Feng, Qian Zhou, Wen Jiang, Yibo Dai, Yang Jiang, Xiaoli Liu, Shuo Li, Yongjing Wang, Fang Wang, Ai Li & Chengyun Zheng. (2020) Novel Small Molecular Compound AE-848 Potently Induces Human Multiple Myeloma Cell Apoptosis by Modulating the NF-κB and PI3K/Akt/mTOR Signaling Pathways. OncoTargets and Therapy 13, pages 13063-13075.
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Articles from other publishers (1)

Fanny Pojero, Paola Poma, Virginia Spanò, Alessandra Montalbano, Paola Barraja & Monica Notarbartolo. (2019) Targeting multiple myeloma with natural polyphenols. European Journal of Medicinal Chemistry 180, pages 465-485.
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