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Original Research

Identifying risk factors for high-dose methotrexate-induced toxicities in children with acute lymphoblastic leukemia

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Pages 6265-6274 | Published online: 05 Jul 2019

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

Wenshu Li, Jiayi Mo, Zhilin Yang, Zhigang Zhao & Shenghui Mei. (2024) Risk factors associated with high-dose methotrexate induced toxicities. Expert Opinion on Drug Metabolism & Toxicology 0:0, pages 1-12.
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Min Zhan, Ze-bin Chen, Chang-cai Ding, Qiang Qu, Guo-qiang Wang, Sixi Liu & Fei-qiu Wen. (2021) Machine learning to predict high-dose methotrexate-related neutropenia and fever in children with B-cell acute lymphoblastic leukemia. Leukemia & Lymphoma 62:10, pages 2502-2513.
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Rizal Husaini Razali, Mohd Nur Fakhruzzaman Noorizhab, Hisyam Jamari, Richard Johari James, Kok Hoi Teh, Hishamshah Mohd Ibrahim, Lay Kek Teh & Mohd Zaki Salleh. (2020) Association of ABCC2 with levels and toxicity of methotrexate in Malaysian Childhood Acute Lymphoblastic Leukemia (ALL). Pediatric Hematology and Oncology 37:3, pages 185-197.
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Articles from other publishers (12)

Meixiang Wang, Jia Fang, Xiaoyan Hu, Tingting Cai, Fulei Wu & Yan Lin. (2024) Chemotherapy-related symptoms in children with leukemia: application of latent profile analysis and network analysis. Supportive Care in Cancer 32:3.
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Randal K. Buddington, Thomas Wong, Karyl K. Buddington, Torben S. Mikkelsen, Xueyuan Cao & Scott C. Howard. (2023) Early clinical indicators of acute kidney injury caused by administering high-dose methotrexate therapy to juvenile pigs. Frontiers in Nephrology 3.
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Rachel D. Harris, Melanie Brooke Bernhardt, Mark C. Zobeck, Olga A. Taylor, Maria Monica Gramatges, Eric S. Schafer, Philip J. Lupo, Karen R. Rabin, Michael E. Scheurer & Austin L. Brown. (2023) Ethnic‐specific predictors of neurotoxicity among patients with pediatric acute lymphoblastic leukemia after high‐dose methotrexate. Cancer 129:8, pages 1287-1294.
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Rim Rakez, Wiem Boufrikha, Areej Cheffaï, Sarra Boukhriss & Mohamed Adnene Laatiri. (2022) High-dose methotrexate-related pneumonitis in a child with acute lymphoblastic leukemia. Journal of Oncology Pharmacy Practice 29:2, pages 506-510.
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Somayeh Shahani, Nasrin Mehraban, Fereshteh Talebpour Amiri, Seyed Mohammad Abedi, Zohreh Noaparast & Salam Mohammadinia. (2022) Melissa Officinalis L. aqueous extract pretreatment decreases methotrexate-induced hepatotoxicity at lower dose and increases 99mTc-phytate liver uptake, as a probe of liver toxicity assessment, in rats. Annals of Nuclear Medicine 37:3, pages 166-175.
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Shaimaa Barakat, Hala Assem, Mostafa Salama, Neveen Mikhael & Yasmine El Chazli. (2022) Is hypoalbuminemia a risk factor for high-dose methotrexate toxicity in children with acute lymphoblastic leukemia?. Journal of the Egyptian National Cancer Institute 34:1.
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Shota Kadomura, Shungo Imai, Kenji Momo, Yuki Sato, Hitoshi Kashiwagi, Tatsuya Itoh, Mitsuru Sugawara & Yoh Takekuma. (2021) Effects of piperacillin/tazobactam or cefepime on folinate dose in patients receiving high-dose methotrexate: A retrospective cohort study using Japanese administrative claims data. Journal of Oncology Pharmacy Practice 28:7, pages 1534-1542.
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Sanjeev Khera, Gaurav Sharma, Vandana Negi & Subhash Chandra Shaw. (2022) Hypoalbuminemia and not undernutrition predicts high‐dose methotrexate‐induced nephrotoxicity in children with acute lymphoblastic leukemia in resource‐constrained centers. Pediatric Blood & Cancer 69:9.
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Haixiao Wu, Guijun Xu, Zhijun Li, Yao Xu, Yile Lin, Vladimir P. Chekhonin, Karl Peltzer, Jun Wang, Shu Li, Huiyang Li, Jin Zhang, Yuan Xue, Wenjuan Ma, Xin Wang & Chao Zhang. (2022) Nomogram predicting leukopenia in osteosarcoma after high-dose methotrexate chemotherapy. Aging 14:12, pages 5023-5033.
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Marc Ghannoum, Darren M. Roberts, David S. Goldfarb, Jesper Heldrup, Kurt Anseeuw, Tais F. Galvao, Thomas D. Nolin, Robert S. Hoffman, Valery Lavergne, Paul Meyers, Sophie Gosselin, Tudor Botnaru, Karine Mardini & David M. Wood. (2022) Extracorporeal Treatment for Methotrexate Poisoning. Clinical Journal of the American Society of Nephrology 17:4, pages 602-622.
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Ian J. Cohen. (2021) Folinic acid over rescue of high dose methotrexate: How problematic citations conserve discredited concepts. Medical Hypotheses 146, pages 110467.
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Richa Rathore, Katharine E. Caldwell, Charles Schutt, Caitlyn B. Brashears, Bethany C. Prudner, William R. Ehrhardt, Cheuk Hong Leung, Heather Lin, Najat C. Daw, Hannah C. Beird, Abigail Giles, Wei-Lien Wang, Alexander J. Lazar, John S.A. Chrisinger, J. Andrew Livingston & Brian A. Van Tine. (2021) Metabolic compensation activates pro-survival mTORC1 signaling upon 3-phosphoglycerate dehydrogenase inhibition in osteosarcoma. Cell Reports 34:4, pages 108678.
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