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Cancer Management and Research Volume 11, 2019 - Issue
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Original Research

Baohuoside I Inhibits the Proliferation of Pancreatic Cancer Cells via mTOR/S6K1-Caspases/Bcl2/Bax Apoptotic Signaling

Fubiao Ni1 Key Laboratory of Diagnosis and Treatment of Severe Hepato-Pancreatic Diseases of Zhejiang Province, Zhejiang Provincial Top Key Discipline in Surgery, First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, People’s Republic of ChinaORCID Iconhttps://orcid.org/0000-0002-2698-9705
ORCID Icon,
Hengjie Tang1 Key Laboratory of Diagnosis and Treatment of Severe Hepato-Pancreatic Diseases of Zhejiang Province, Zhejiang Provincial Top Key Discipline in Surgery, First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, People’s Republic of China
,
Cheng Wang1 Key Laboratory of Diagnosis and Treatment of Severe Hepato-Pancreatic Diseases of Zhejiang Province, Zhejiang Provincial Top Key Discipline in Surgery, First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, People’s Republic of China
,
Hewei Zhang1 Key Laboratory of Diagnosis and Treatment of Severe Hepato-Pancreatic Diseases of Zhejiang Province, Zhejiang Provincial Top Key Discipline in Surgery, First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, People’s Republic of ChinaORCID Iconhttps://orcid.org/0000-0003-1784-4026
ORCID Icon,
Chenlei Zheng1 Key Laboratory of Diagnosis and Treatment of Severe Hepato-Pancreatic Diseases of Zhejiang Province, Zhejiang Provincial Top Key Discipline in Surgery, First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, People’s Republic of China
,
Ning Zhang2 First School of Clinical Medicine, Wenzhou Medical University, Wenzhou, Zhejiang 325000, People’s Republic of China
,
Bicheng Chen1 Key Laboratory of Diagnosis and Treatment of Severe Hepato-Pancreatic Diseases of Zhejiang Province, Zhejiang Provincial Top Key Discipline in Surgery, First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, People’s Republic of China
&
Linxiao Sun1 Key Laboratory of Diagnosis and Treatment of Severe Hepato-Pancreatic Diseases of Zhejiang Province, Zhejiang Provincial Top Key Discipline in Surgery, First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, People’s Republic of ChinaCorrespondence[email protected] [email protected]
ORCID Iconhttps://orcid.org/0000-0001-5849-4881
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Pages 10609-10621 | Published online: 19 Dec 2019

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Zhong Zhang & Hai-Jun Zhang. (2021) Glycometabolic rearrangements–aerobic glycolysis in pancreatic ductal adenocarcinoma (PDAC): roles, regulatory networks, and therapeutic potential. Expert Opinion on Therapeutic Targets 25:12, pages 1077-1093.
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Articles from other publishers (6)

Xudong Ao, Chao Luo, Mengni Zhang, Lisha Liu & Shunlin Peng. (2023) The efficacy of natural products for the treatment of nasopharyngeal carcinoma. Chemical Biology & Drug Design 103:1.
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Yi Lu, Qiulan Luo, Xiaobin Jia, James P. Tam, Huan Yang, Yuping Shen & Xin Li. (2023) Multidisciplinary strategies to enhance therapeutic effects of flavonoids from Epimedii Folium: Integration of herbal medicine, enzyme engineering, and nanotechnology. Journal of Pharmaceutical Analysis 13:3, pages 239-254.
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Lizhen Chen, Dayun Yu, Shuang Ling & Jin-Wen Xu. (2022) Mechanism of tonifying-kidney Chinese herbal medicine in the treatment of chronic heart failure. Frontiers in Cardiovascular Medicine 9.
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Shan Lu, Kang Zou, Biying Guo, Jianjun Pei, Zhenzhong Wang, Wei Xiao & Linguo Zhao. (2022) One-step purification and immobilization of thermostable β-glucosidase on Na-Y zeolite based on the linker and its application in the efficient production of baohuoside I from icariin. Bioorganic Chemistry 121, pages 105690.
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Yanyi Xiao, Yilong Liu, Zhiwei Gao, Xian Li, Min Weng, Chenghao Shi, Cheng Wang & Linxiao Sun. (2021) Fisetin inhibits the proliferation, migration and invasion of pancreatic cancer by targeting PI3K/AKT/mTOR signaling. Aging 13:22, pages 24753-24767.
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Fei Xu, Qiaolan Wu, Lei Li, Jie Gong, Ran Huo & Wenqiang Cui. (2021) Icariside II: Anticancer Potential and Molecular Targets in Solid Cancers. Frontiers in Pharmacology 12.
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