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Original Research

CircFLNA Acts as a Sponge of miR-646 to Facilitate the Proliferation, Metastasis, Glycolysis, and Apoptosis Inhibition of Gastric Cancer by Targeting PFKFB2

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Pages 8093-8103 | Published online: 07 Sep 2020

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Shuangquan Lin, Lei Wang, Zimin Shi, Anyi Zhu, Gan Zhang, Zhengdong Hong & Cheng Cheng. (2021) Circular RNA circFLNA inhibits the development of bladder carcinoma through microRNA miR-216a-3p/BTG2 axis. Bioengineered 12:2, pages 11376-11389.
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Articles from other publishers (13)

Juan Sun, Jie Li, Yixuan He, Weiming Kang & Xin Ye. (2024) Identification and Validation of Protein Biomarkers for Predicting Gastrointestinal Stromal Tumor Recurrence. Computational and Structural Biotechnology Journal.
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Jiankun Ren, Songwei Zhao & Junyu Lai. (2024) Triptolide restrains the growth, invasion, stemness, and glycolysis of non‐small cell lung cancer cells by PFKFB2 ‐mediated PI3K / AKT pathway . Chemical Biology & Drug Design 103:1.
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Yuntian Hong, Baoxiang Chen, Chun Wang, Rui Gui, Xiang Zhai, Qun Qian, Xianghai Ren, Xiaoyu Xie & Congqing Jiang. (2023) circPPP2R4 promotes colorectal cancer progression and reduces ROS production through the miR‐646/FOXK1 axis. Molecular Carcinogenesis 63:1, pages 106-119.
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Maaike Schilperoort, David Ngai, Santosh R. Sukka, Kleopatra Avrampou, Hongxue Shi & Ira Tabas. (2023) The role of efferocytosis‐fueled macrophage metabolism in the resolution of inflammation. Immunological Reviews 319:1, pages 65-80.
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Maaike Schilperoort, David Ngai, Marina Katerelos, David A. Power & Ira Tabas. (2023) PFKFB2-mediated glycolysis promotes lactate-driven continual efferocytosis by macrophages. Nature Metabolism 5:3, pages 431-444.
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Ze-Rong Cai, Yan Hu, Kun Liao, Hao Li, Dong-Liang Chen & Huai-Qiang Ju. (2023) Circular RNAs: Emerging regulators of glucose metabolism in cancer. Cancer Letters 552, pages 215978.
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Xingjie Shen, Xiaoyan Zhu, Peixin Hu, Tingting Ji, Ying Qin & Jingyu Zhu. (2022) Knockdown circZNF131 Inhibits Cell Progression and Glycolysis in Gastric Cancer Through miR-186-5p/PFKFB2 Axis. Biochemical Genetics 60:5, pages 1567-1584.
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Jianing Yan, Yongfu Shao, Haoxuan Lu, Qihua Ye, Guoliang Ye & Junming Guo. (2021) Hsa_circ_0001020 Serves as a Potential Biomarker for Gastric Cancer Screening and Prognosis. Digestive Diseases and Sciences 67:8, pages 3753-3762.
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Hang Li, Lixin Chai, Zujun Ding & Huabo He. (2022) CircCOL1A2 Sponges MiR-1286 to Promote Cell Invasion and Migration of Gastric Cancer by Elevating Expression of USP10 to Downregulate RFC2 Ubiquitination Level. Journal of Microbiology and Biotechnology 32:7, pages 938-948.
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Limin Miao, Guanying Feng & Hua Yuan. (2021) CircRNAs: a family number of miRNA regulatory transcriptome in laryngeal carcinoma. Journal of Clinical Laboratory Analysis 35:11.
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Yu Sun, Guangtao Ma, Hongtao Xiang, Xiaomin Wang, Hanmei Wang, Yan Zhang, Fuzhong Qie & Chenlong Li. (2021) circFLNA promotes glioblastoma proliferation and invasion by negatively regulating miR‑199‑3p expression. Molecular Medicine Reports 24:5.
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Xiwu Ouyang, Lemeng Feng, Lei Yao, Yao Xiao, Xianyu Hu, Gewen Zhang, Guodong Liu & Zhiming Wang. (2021) Testicular orphan receptor 4 (TR4) promotes papillary thyroid cancer invasion via activating circ-FNLA/miR-149-5p/MMP9 signaling. Molecular Therapy - Nucleic Acids 24, pages 755-767.
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Bo Wang, Ye Lu & Eryan Feng. (2021) hsa_circ_0001610 knockdown modulates miR‐646‐STAT3 axis to suppress endometrial carcinoma progression. The Journal of Gene Medicine 23:6.
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