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Original Research

Lymphocyte-to-Monocyte Ratio is Associated with the Poor Prognosis of Breast Cancer Patients Receiving Neoadjuvant Chemotherapy

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Pages 1571-1580 | Published online: 16 Feb 2021

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Xin Hua, Fangfang Duan, Wenyu Zhai, Chenge Song, Chang Jiang, Li Wang, Jiajia Huang, Huanxin Lin & Zhongyu Yuan. (2022) A Novel Inflammatory-Nutritional Prognostic Scoring System for Patients with Early-Stage Breast Cancer. Journal of Inflammation Research 15, pages 381-394.
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Yuye Chen, Zheming Guan & Guo Shen. (2022) Naples Prognostic Score: A Novel Predictor of Survival in Patients with HER2-Positive Breast Cancer. Future Oncology 18:21, pages 2655-2665.
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Hong-Yu Wu, Chin-Yao Lin, Yen-Dun Tzeng, Chih-Chiang Hung, Shiuh-Inn Liu, Chun-Hao Yin, Jin-Shuen Chen, Yao-Shen Chen & Jie-Ru Yang. (2023) Preoperative systemic inflammation response index: Clinicopathologic predictor of pathological complete response in HER2-positive breast cancer patients receiving neoadjuvant systemic therapy. Journal of the Chinese Medical Association 87:2, pages 226-235.
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Sonar Soni Panigoro, Arga Patrianagara, Ninik Sukartini, Trevino Aristarkus Pakasi & Samuel Johny Haryono. (2024) Inflammatory indicators as a prognostic factor of clinical response in locally advanced breast cancer (LABC) patients receiving neoadjuvant chemotherapy (NAC). Revista de Senología y Patología Mamaria 37:1, pages 100553.
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Stefanos Ioannis Moukas, Sabine Kasimir-Bauer, Mitra Tewes, Hans-Christian Kolberg, Oliver Hoffmann, Rainer Kimmig & Corinna Keup. (2023) Ratios of monocytes and neutrophils to lymphocytes in the blood predict benefit of CDK4/6 inhibitor treatment in metastatic breast cancer. Scientific Reports 13:1.
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Atlal Abusanad. (2023) Utilizing peripheral blood inflammatory biomarker (PBIB) to predict response to systemic therapy in patients with breast cancer. Journal of Family Medicine and Primary Care 12:12, pages 3368-3373.
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Jiaqiang Xie, Zhenxi Guo, Yijing Zhu, Mingde Ma & Guangwei Jia. (2023) Peripheral blood inflammatory indexes in breast cancer: A review. Medicine 102:48, pages e36315.
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Corinna Keup, Rainer Kimmig & Sabine Kasimir-Bauer. (2023) The Diversity of Liquid Biopsies and Their Potential in Breast Cancer Management. Cancers 15:22, pages 5463.
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Xue Qi, Jia Chen, Sheng Wei, Jingyi Ni, Li Song, Conghui Jin, Lei Yang & Xunlei Zhang. (2023) Prognostic significance of platelet-to-lymphocyte ratio (PLR) in patients with breast cancer treated with neoadjuvant chemotherapy: a meta-analysis. BMJ Open 13:11, pages e074874.
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Gerard Feeney, Ronan Waldron, Nicola Miller, Carmel Malone, Karl Sweeney, Raymond McLaughlin, Aoife Lowery, Kevin Barry & Michael Kerin. (2023) Association of clinical biomarkers and response to neoadjuvant therapy in breast cancer. Irish Journal of Medical Science (1971 -).
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Hakan Balbaloglu, Ilhan TasdovenGuldeniz Karadeniz Cakmak. (2023) Can inflammatory indices predict sentinel lymph node status in patients with early-stage breast cancer?. Medicine 102:33, pages e34808.
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Chuangye Qiu, Shizhen Liu, Xingai Li, Wenxia Li, Guoqiang Hu & Fanna Liu. (2023) Prognostic value of monocyte-to-lymphocyte ratio for 90-day all-cause mortality in type 2 diabetes mellitus patients with chronic kidney disease. Scientific Reports 13:1.
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Natalia S. Sergeeva, Tatiana A. Karmakova, Marianna A. Polyak & Igor I. Alentov. (2023) Systemic Inflammatory Response as a Prognostic Factor in Breast Cancer. Part II. Hematological Markers of Inflammation. Annals of the Russian academy of medical sciences 77:6, pages 408-419.
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Pauline Rottier, George Emile, Alison Johnson, Christelle Levy, Djelila Allouache, Ioana Hrab, Carine Segura, Adeline Morel, Maud Villemin, Coraline Dubot-Poitelon, Louis Boismoreau, François Cherifi, Justine Lequesne & Angélique Da Silva. (2023) Pretreatment neutrophil to lymphocyte ratio as prognostic factor in metastatic breast cancer treated with cyclin dependent kinase 4/6 inhibitors. Frontiers in Oncology 12.
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Burcu Tunay, Omer Fatih Olmez, Ahmet Bilici, Ayberk Bayramgil, Gunes Dorukhan Cavusoglu & Huseyin Oz. (2023) The modified Glasgow prognostic score (MGPS) and the mortality prediction model II (MPM II) can predict mortality in patients with breast cancer admitted to intensive care: A retrospective cohort study. Journal of Surgery and Medicine 7:1, pages 6-10.
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Yajiao Liu, Li Sheng, Haiying Hua, Jingfen Zhou, Ying Zhao & Bei Wang. (2023) An Externally Validated Nomogram for Predicting the Overall Survival of Patients With Diffuse Large B-Cell Lymphoma Based on Clinical Characteristics and Systemic Inflammatory Markers. Technology in Cancer Research & Treatment 22.
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Xiao-Yu Chen, Zhi-Qing Long, Han-Ying Huang, Wen Wen, Fei Lin, Ling Guo & Huan-Xin Lin. (2023) Predicting Survival of Patients with Nonmetastatic Breast Cancer Based on Fibrinogen-to-Albumin Ratio and Lymphocyte-to-Monocyte Ratio: A Nomogram-Based Assessment. Breast Care 18:5, pages 374-389.
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Caterina Gianni, Michela Palleschi, Filippo Merloni, Sara Bleve, Chiara Casadei, Marianna Sirico, Giandomenico Di Menna, Samanta Sarti, Lorenzo Cecconetto, Marita Mariotti & Ugo De Giorgi. (2022) Potential Impact of Preoperative Circulating Biomarkers on Individual Escalating/de-Escalating Strategies in Early Breast Cancer. Cancers 15:1, pages 96.
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Haa-Na Song, Ju Yeon Kim, Jae Myung Kim, Ki Mun Kang, Hoon Sik Choi, Jin Hee Jeong, In Bong HaBae-Kwon Jeong. (2022) Sarcopenia using pectoralis muscle area and lymphocyte-to-monocyte ratio (LMR) are independent prognostic factors in patients for nonmetastatic breast cancer. Medicine 101:49, pages e32229.
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Elisabet Rodríguez-Tomàs, Meritxell Arenas, Gerard Baiges-Gaya, Johana Acosta, Pablo Araguas, Bárbara Malave, Helena Castañé, Andrea Jiménez-Franco, Rocío Benavides-Villarreal, Sebastià Sabater, Rosa Solà-Alberich, Jordi Camps & Jorge Joven. (2022) Gradient Boosting Machine Identified Predictive Variables for Breast Cancer Patients Pre- and Post-Radiotherapy: Preliminary Results of an 8-Year Follow-Up Study. Antioxidants 11:12, pages 2394.
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Sabine Kasimir-Bauer, Ebru Karaaslan, Olaf Hars, Oliver Hoffmann & Rainer Kimmig. (2022) In Early Breast Cancer, the Ratios of Neutrophils, Platelets and Monocytes to Lymphocytes Significantly Correlate with the Presence of Subsets of Circulating Tumor Cells but Not with Disseminated Tumor Cells. Cancers 14:14, pages 3299.
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Eda Tanrıkulu Şimşek, Batuhan Bayram, Alev Yıldırım & Ahmet Emre Eşkazan. (2022) Is it possible to predict the pCR with CBC? A commentary on “correlation analysis of lymphocyte-monocyte ratio with pathological complete response and clinical prognosis of neoadjuvant chemotherapy in patients with breast cancer” by Meng et al.. Translational Oncology 20, pages 101403.
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Dooreh Kim, Soong June Bae, Sung Gwe Ahn, Joon Jeong, Seho Park, Woo-Chan Park, Goeun Park, Sujee Lee & Chang Ik Yoon. (2022) RT-induced dynamic changes in the lymphocyte-to-monocyte ratio in patients with breast cancer indicate poor prognosis. Breast Cancer Research and Treatment 193:3, pages 637-647.
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Agnieszka Pikuła, Magdalena Skórzewska, Zuzanna Pelc, Radosław Mlak, Katarzyna Gęca, Katarzyna Sędłak, Bogumiła Ciseł, Magdalena Kwietniewska, Karol Rawicz-Pruszyński & Wojciech P. Polkowski. (2022) Prognostic Value of Systemic Inflammatory Response Markers in Patients Undergoing Neoadjuvant Chemotherapy and Gastrectomy for Advanced Gastric Cancer in the Eastern European Population. Cancers 14:8, pages 1997.
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Zihan Zhang, Qian Lin, Yi Chen, Chenlin Su, Wuye Lin, Daoyu Wei, Litu Zhang & Haizhou Liu. (2022) Prognostic Evaluation of Metastasis-Related Lymphocyte/Monocyte Ratio in Stage Ⅰ-Ⅲ Breast Cancer Receiving Chemotherapy. Frontiers in Oncology 11.
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珊 高. (2022) Research Progress on the Relationship between Hematological Inflammatory Indexes and Prognosis of Breast Cancer. Advances in Clinical Medicine 12:12, pages 11867-11872.
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Ahmet Bilgehan Şahin, Erdem Cubukcu, Birol Ocak, Adem Deligonul, Sibel Oyucu Orhan, Sahsine Tolunay, Mustafa Sehsuvar Gokgoz, Sibel Cetintas, Gorkem Yarbas, Kazım Senol, Mehmet Refik Goktug, Zeki Burak Yanasma, Ulviyya Hasanzade & Turkkan Evrensel. (2021) Low pan-immune-inflammation-value predicts better chemotherapy response and survival in breast cancer patients treated with neoadjuvant chemotherapy. Scientific Reports 11:1.
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