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Review

RUNX2 as a promising therapeutic target for malignant tumors

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Pages 2539-2548 | Published online: 16 Mar 2021

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Dhrubo Ahmed Khan, Tonmoy Adhikary, Mst. Tania Sultana & Imran Ahamed Toukir. (2023) A comprehensive identification of potential molecular targets and small drugs candidate for melanoma cancer using bioinformatics and network-based screening approach. Journal of Biomolecular Structure and Dynamics 0:0, pages 1-21.
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Amir Abbas Hamidi, Malihe Zangoue, Daniel Kashani, Amir Sadra Zangouei, Hamid Reza Rahimi, Mohammad Reza Abbaszadegan & Meysam Moghbeli. (2022) MicroRNA-217: a therapeutic and diagnostic tumor marker. Expert Review of Molecular Diagnostics 22:1, pages 61-76.
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Articles from other publishers (14)

Shuai Gong, Yi Zhang, Lina Pang, Liye Wang & Wei He. (2023) A novel CircRNA Circ_0001722 regulates proliferation and invasion of osteosarcoma cells through targeting miR-204-5p/RUNX2 axis. Journal of Cancer Research and Clinical Oncology 149:14, pages 12779-12790.
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Milena Krajnović, Bojana Kožik, Ana Božović & Snežana Jovanović-Ćupić. (2023) Multiple Roles of the RUNX Gene Family in Hepatocellular Carcinoma and Their Potential Clinical Implications. Cells 12:18, pages 2303.
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Hamidreza Montazeri Aliabadi, Arthur Manda, Riya Sidgal & Co Chung. (2023) Targeting Breast Cancer: The Familiar, the Emerging, and the Uncharted Territories. Biomolecules 13:9, pages 1306.
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Gisella Bermúdez, Camila Bernal, Andrea Otalora, Paula Sanchez, Gino Nardocci, Alejandra Cañas, Liliana Lopez-Kleine, Martín Montecino & Adriana Rojas. (2023) Long Noncoding RNA TALAM1 Is a Transcriptional Target of the RUNX2 Transcription Factor in Lung Adenocarcinoma. Current Issues in Molecular Biology 45:9, pages 7075-7086.
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Vivien Hild, Kevin Mellert, Peter Möller & Thomas F. E. Barth. (2023) Giant Cells of Various Lesions Are Characterised by Different Expression Patterns of HLA-Molecules and Molecules Involved in the Cell Cycle, Bone Metabolism, and Lineage Affiliation: An Immunohistochemical Study with a Review of the Literature. Cancers 15:14, pages 3702.
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Lawrence P. McKinney, Rajesh Singh, I. King Jordan, Sooryanarayana Varambally, Eric B. Dammer & James W. LillardJr.Jr.. (2023) Transcriptome Analysis Identifies Tumor Immune Microenvironment Signaling Networks Supporting Metastatic Castration-Resistant Prostate Cancer. Onco 3:2, pages 81-95.
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Beihui Huang, Huixin Liu, Szehoi Chan, Junru Liu, Jingli Gu, Meilan Chen, Lifen Kuang, Xiaozhe Li, Xingding Zhang & Juan Li. (2023) RUNX2 promotes the suppression of osteoblast function and enhancement of osteoclast activity by multiple myeloma cells. Medical Oncology 40:4.
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Ping Wang, Jiajia Zhang, Hui Zhang & Fang Zhang. (2022) The role of MACF1 on acute myeloid leukemia cell proliferation is involved in Runx2-targeted PI3K/Akt signaling. Molecular and Cellular Biochemistry 478:3, pages 433-441.
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NINGYU LI, XIAOFANG CHEN, SUXIA GENG, PEILONG LAI, LISI HUANG, MINMING LI, XIN HUANG, CHENGXIN DENG, YULIAN WANG, JIANYU WENG & XIN DU. (2023) miR-103-3p regulates the differentiation of bone marrow mesenchymal stem cells in myelodysplastic syndrome. BIOCELL 47:1, pages 133-141.
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Nicolas Thomas Iannozzi, Valentina Marchica, Denise Toscani, Jessica Burroughs Garcìa, Nicola Giuliani & Paola Storti. (2022) Molecular Features of the Mesenchymal and Osteoblastic Cells in Multiple Myeloma. International Journal of Molecular Sciences 23:24, pages 15448.
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Camila Bernal, Andrea Otalora, Alejandra Cañas, Alfonso Barreto, Karol Prieto, Martin Montecino & Adriana Rojas. (2022) Regulatory Role of the RUNX2 Transcription Factor in Lung Cancer Apoptosis. International Journal of Cell Biology 2022, pages 1-13.
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Manuel Joaquín Romero-López, Hilda Jiménez-Wences, Merlin Itsel Cruz-De la Rosa, Ilce Valeria Román-Fernández & Gloria Fernández-Tilapa. (2022) miR-23b-3p, miR-124-3p and miR-218-5p Synergistic or Additive Effects on Cellular Processes That Modulate Cervical Cancer Progression? A Molecular Balance That Needs Attention. International Journal of Molecular Sciences 23:21, pages 13551.
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Li Zeng, Hong He, Mingjie Sun, Xinyi Gong, Mengqi Zhou, Yaya Hong, Yongjia Wu, Xuepeng Chen & Qianming Chen. (2022) Runx2 and Nell-1 in dental follicle progenitor cells regulate bone remodeling and tooth eruption. Stem Cell Research & Therapy 13:1.
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Merlin Itsel Cruz-De la Rosa, Hilda Jiménez-Wences, Judit Alarcón-Millán, Manuel Joaquín Romero-López, Carlos Alberto Castañón-Sánchez, Eric Genaro Salmerón-Bárcenas & Gloria Fernández-Tilapa. (2022) miR-218-5p/RUNX2 Axis Positively Regulates Proliferation and Is Associated with Poor Prognosis in Cervical Cancer. International Journal of Molecular Sciences 23:13, pages 6993.
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