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Original Research

Fine-particulate matter aggravates cigarette smoke extract–induced airway inflammation via Wnt5a–ERK pathway in COPD

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Pages 979-994 | Published online: 09 May 2019

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Weifeng Zou, Xiaoqian Wang, Ruiting Sun, Jinxing Hu, Dong Ye, Ge Bai, Sha Liu, Wei Hong, Meihua Guo & Pixin Ran. (2021) PM2.5 Induces Airway Remodeling in Chronic Obstructive Pulmonary Diseases via the Wnt5a/β-Catenin Pathway. International Journal of Chronic Obstructive Pulmonary Disease 16, pages 3285-3295.
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Stéphanie Alkoussa, Sébastien Hulo, Dominique Courcot, Sylvain Billet & Perrine J. Martin. (2020) Extracellular vesicles as actors in the air pollution related cardiopulmonary diseases. Critical Reviews in Toxicology 50:5, pages 402-423.
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Weifeng Zou, Xiaoqian Wang, Wei Hong, Fang He, Jinxing Hu, Qing Sheng, Tao Zhu & Pixin Ran. (2020) PM2.5 Induces the Expression of Inflammatory Cytokines via the Wnt5a/Ror2 Pathway in Human Bronchial Epithelial Cells. International Journal of Chronic Obstructive Pulmonary Disease 15, pages 2653-2662.
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Articles from other publishers (13)

Abhinav Singla, Sebastian Reuter, Christian Taube, Marcus Peters & Karin Peters. (2023) The molecular mechanisms of remodeling in asthma, COPD and IPF with a special emphasis on the complex role of Wnt5A. Inflammation Research 72:3, pages 577-588.
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Qian Huang, Maocuo Peng, Yiya Gu, Jixing Wu, Yuan Zhan, Zhesong Deng, Shanshan Chen, Ruonan Yang, Jinkun Chen & Jungang Xie. (2022) Metabolism-Related Gene TXNRD1 Regulates Inflammation and Oxidative Stress Induced by Cigarette Smoke through the Nrf2/HO-1 Pathway in the Small Airway Epithelium. Oxidative Medicine and Cellular Longevity 2022, pages 1-16.
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Jixing Wu, Qian Huang, Qinghai Li, Yiya Gu, Yuan Zhan, Ting Wang, Jinkun Chen, Zhilin Zeng, Yongman Lv, Jianping Zhao, Jie Xia & Jungang Xie. (2022) Increased Methyl-CpG-Binding Domain Protein 2 Promotes Cigarette Smoke-Induced Pulmonary Hypertension. Frontiers in Oncology 12.
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Yinglin Wu, Shiyu Zhang, Bingting Zhuo, Miao Cai, Zhengmin Min Qian, Michael G. Vaughn, Stephen Edward McMillin, Zilong Zhang & Hualiang Lin. (2022) Global burden of chronic obstructive pulmonary disease attributable to ambient particulate matter pollution and household air pollution from solid fuels from 1990 to 2019. Environmental Science and Pollution Research 29:22, pages 32788-32799.
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Ching Leng Tan, Yinghan Chan, Mayuren Candasamy, Jestin Chellian, Thiagarajan Madheswaran, Lakshmana Prabu Sakthivel, Vyoma K. Patel, Amlan Chakraborty, Ronan MacLoughlin, Deepak Kumar, Nitin Verma, Vamshikrishna Malyla, Piyush Kumar Gupta, Niraj Kumar Jha, Lakshmi Thangavelu, Hari Prasad Devkota, Shvetank Bhatt, Parteek Prasher, Gaurav Gupta, Monica Gulati, Sachin Kumar Singh, Keshav Raj Paudel, Philip M. Hansbro, Brian G. Oliver, Kamal Dua & Dinesh Kumar Chellappan. (2022) Unravelling the molecular mechanisms underlying chronic respiratory diseases for the development of novel therapeutics via in vitro experimental models. European Journal of Pharmacology 919, pages 174821.
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Vegard Sæter Grytting, Prem Chand, Marit Låg, Johan Øvrevik & Magne Refsnes. (2022) The pro-inflammatory effects of combined exposure to diesel exhaust particles and mineral particles in human bronchial epithelial cells. Particle and Fibre Toxicology 19:1.
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Jian Zhou, Chuanzong Qi, Xin Fang, Zihao Wang, Shuyi Zhang, Dalang Li & Jue Song. (2021) DJ-1 modulates Nrf2-mediated MRP1 expression by activating Wnt3a/β-catenin signalling in A549 cells exposed to cigarette smoke extract and LPS. Life Sciences 276, pages 119089.
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Rui Ye, Cuihong Wang, Pengbo Sun, Shuang Bai & Li Zhao. (2021) AGR3 Regulates Airway Epithelial Junctions in Patients with Frequent Exacerbations of COPD. Frontiers in Pharmacology 12.
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Faxue Zhang, Yuanyuan Zhang, Linjiong Liu, Anqi Jiao, Dieyi Chen, Qianqian Xiang, Jiaying Fang, Zan Ding & Yunquan Zhang. (2021) Assessing PM2.5-associated risk of hospitalization for COPD: an application of daily excessive concentration hours. Environmental Science and Pollution Research 28:23, pages 30267-30277.
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Yixuan Zhang, Lu Wang, Gökhan M. Mutlu & Hua Cai. (2021) More to Explore: Further Definition of Risk Factors for COPD – Differential Gender Difference, Modest Elevation in PM2.5, and e-Cigarette Use. Frontiers in Physiology 12.
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Yang Lan, Cheng Teng Ng, Choon Nam Ong, Liya E. Yu & Boon Huat Bay. (2021) Transcriptomic analysis identifies dysregulated genes and functional networks in human small airway epithelial cells exposed to ambient PM2.5. Ecotoxicology and Environmental Safety 208, pages 111702.
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Eun Suk Son, Jeong-Woong Park, Yu Jin Kim, Sung Hwan Jeong, Jeong Hee Hong, Se-Hee Kim & Sun Young Kyung. (2020) Effects of antioxidants on oxidative stress and inflammatory responses of human bronchial epithelial cells exposed to particulate matter and cigarette smoke extract. Toxicology in Vitro 67, pages 104883.
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Jing Wang, Ya Li, Peng Zhao, Yange Tian, Xuefang Liu, Huihui He, Rui Jia, Brian G. Oliver & Jiansheng Li. (2020) Exposure to Air Pollution Exacerbates Inflammation in Rats with Preexisting COPD. Mediators of Inflammation 2020, pages 1-12.
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