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Clinical Trial Report

Clinical Significance of Bronchodilator Responsiveness Evaluated by Forced Vital Capacity in COPD: SPIROMICS Cohort Analysis

Igor Z Barjaktarevic1 Department of Medicine, University of California, Los Angeles, Los Angeles, CA, USA

Russell G Buhr1 Department of Medicine, University of California, Los Angeles, Los Angeles, CA, USA;2 Department of Health Policy and Management, Fielding School of Public Health, University of California, Los Angeles, Los Angeles, CA, USA

https://orcid.org/0000-0001-6159-7435

Xiaoyan Wang3 Department of General Internal Medicine and Health Services Research, University of California, Los Angeles, Los Angeles, CA, USA

Scott Hu1 Department of Medicine, University of California, Los Angeles, Los Angeles, CA, USA

David Couper4 Department of Medicine, University of North Carolina, Chapel Hill, NC, USA

https://orcid.org/0000-0002-4313-9235

Wayne Anderson4 Department of Medicine, University of North Carolina, Chapel Hill, NC, USA

Richard E Kanner5 Department of Medicine, University of Utah, Salt Lake City, UT, USA

https://orcid.org/0000-0001-6915-599X

Robert Paine III5 Department of Medicine, University of Utah, Salt Lake City, UT, USA

Surya P Bhatt6 Division of Pulmonary, Allergy and Critical Care Medicine, University of Alabama at Birmingham, Birmingham, AL, USA

https://orcid.org/0000-0002-8418-4497

Nirav R Bhakta7 Department of Medicine, University of California, San Francisco, San Francisco, CA, USA

https://orcid.org/0000-0002-2135-7012

Mehrdad Arjomandi7 Department of Medicine, University of California, San Francisco, San Francisco, CA, USA

https://orcid.org/0000-0002-0116-9217

Robert J Kaner8 Department of Medicine, Weill Cornell Weill Cornell Medical Center, New York, NY, USA

https://orcid.org/0000-0003-0527-576X

Cheryl S Pirozzi5 Department of Medicine, University of Utah, Salt Lake City, UT, USA

https://orcid.org/0000-0002-1533-1916

Jeffrey L Curtis9 Department of Medicine, University of Michigan, Ann Arbor, MI, USA;10 Medicine Service, VA Ann Arbor Healthcare System, Ann Arbor, MI, USA

https://orcid.org/0000-0001-5191-4847

Wanda K O’Neal4 Department of Medicine, University of North Carolina, Chapel Hill, NC, USA

Prescott G Woodruff7 Department of Medicine, University of California, San Francisco, San Francisco, CA, USA

MeiLan K Han9 Department of Medicine, University of Michigan, Ann Arbor, MI, USA

Fernando J Martinez8 Department of Medicine, Weill Cornell Weill Cornell Medical Center, New York, NY, USA

https://orcid.org/0000-0002-2412-3182

Nadia Hansel11 Department of Medicine, John Hopkins University, Baltimore, MD, USA

James Michael Wells6 Division of Pulmonary, Allergy and Critical Care Medicine, University of Alabama at Birmingham, Birmingham, AL, USA

Victor E Ortega12 Department of Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA

Eric A Hoffman13 Department of Medicine, University of Iowa, Iowa City, IA, USA

https://orcid.org/0000-0001-8456-9437

Claire M Doerschuk4 Department of Medicine, University of North Carolina, Chapel Hill, NC, USA

Victor Kim14 Department of Thoracic Medicine and Surgery, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA

https://orcid.org/0000-0002-1385-1571

Mark T Dransfield6 Division of Pulmonary, Allergy and Critical Care Medicine, University of Alabama at Birmingham, Birmingham, AL, USA

M Bradley Drummond4 Department of Medicine, University of North Carolina, Chapel Hill, NC, USA

https://orcid.org/0000-0002-6968-4610

Russell Bowler15 Department of Medicine, National Jewish Health Systems, Denver, CO, USA

Gerard Criner14 Department of Thoracic Medicine and Surgery, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA

Stephanie A Christenson7 Department of Medicine, University of California, San Francisco, San Francisco, CA, USA

Bonnie Ronish5 Department of Medicine, University of Utah, Salt Lake City, UT, USA

Stephen P Peters12 Department of Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA

https://orcid.org/0000-0003-4176-7999

Jerry A Krishnan16 Department of Medicine, University of Illinois at Chicago, Chicago, IL, USA

https://orcid.org/0000-0001-5525-4778

Donald P Tashkin1 Department of Medicine, University of California, Los Angeles, Los Angeles, CA, USA

Christopher B Cooper1 Department of Medicine, University of California, Los Angeles, Los Angeles, CA, USACorrespondence[email protected]

& On behalf of the NHLBI SubPopulations and InteRmediate Outcome Measures In COPD Study (SPIROMICS) show all

Clinical Significance of Bronchodilator Responsiveness Evaluated by Forced Vital Capacity in COPD: SPIROMICS Cohort Analysis

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Clinical Significance of Bronchodilator Responsiveness Evaluated by Forced Vital Capacity in COPD: SPIROMICS Cohort Analysis

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