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International Journal of Chronic Obstructive Pulmonary Disease Volume 15, 2020 - Issue
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Review

Nebulized Therapies in COPD: Past, Present, and the Future

Igor Z Barjaktarevic1 Division of Pulmonary and Critical Care Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USAORCID Iconhttps://orcid.org/0000-0002-8096-0858
ORCID Icon &
Aaron P Milstone2 Williamson Medical Center, Franklin, TN, USACorrespondence[email protected]
Pages 1665-1677 | Published online: 12 Jul 2020

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James F Donohue, Tara Rheault, Margot MacDonald-Berko, Thomas Bengtsson & Kathleen Rickard. (2023) Ensifentrine as a Novel, Inhaled Treatment for Patients with COPD. International Journal of Chronic Obstructive Pulmonary Disease 18, pages 1611-1622.
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Seda ŞAHAN, Sevil GÜLER & Eliz GEÇTAN. (2023) Hemşireler, Hasta ve Hasta Yakınlarının Nebulizatör ile İlaç Uygulamalarında Yaptıkları Hataların BelirlenmesiDetermination of the Errors Made by Nurses, Patients, and Patients’ Relatives in Drug Administration with Nebulizers. Sağlık Bilimleri Üniversitesi Hemşirelik Dergisi 5:1, pages 7-16.
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Xiufeng Wu, Zhaoliu Cao, Jiang Ni, Xiaoyuan Zheng, Lizhen Zhu, Xin wang, Juan Lv, Shijun Zhou, Yongjuan Ding & Ruirong Wu. (2023) Compatibility and aerosol characteristics of beclomethasone mixed with N-acetylcysteine. Heliyon 9:4, pages e15357.
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Russell A. Acevedo, Wendy Fascia, Jennifer Pedley, Robert Pikarsky & Viren Kaul. (2023) How to Create a Primary Respiratory Care Model. Chest 163:4, pages 902-910.
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Michael Troy, Joseph Van Vleet, Donald Tashkin & Igor Barjaktarevic. (2023) Recent advances predict a bright future for nebulizers. Current Opinion in Pulmonary Medicine 29:2, pages 123-132.
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Michael Y.T. Chow, Harry W. Pan, Han Cong Seow & Jenny K.W. Lam. (2023) Inhalable neutralizing antibodies – promising approach to combating respiratory viral infections. Trends in Pharmacological Sciences 44:2, pages 85-97.
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Karolina Knap, Konrad Kwiecień, Katarzyna Reczyńska-Kolman & Elżbieta Pamuła. (2023) Inhalable microparticles as drug delivery systems to the lungs in a dry powder formulations. Regenerative Biomaterials 10.
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Hezhi Wang, Lu Qin, Xin Zhang, Jian Guan & Shirui Mao. (2022) Mechanisms and challenges of nanocarriers as non-viral vectors of therapeutic genes for enhanced pulmonary delivery. Journal of Controlled Release 352, pages 970-993.
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Jiayi Li, Sibo Ma, Ying Sun, Ruxiao Song, Baoli Cai, Hao Li, Ying Chen, Xin Zhang, Jian Guan & Shirui Mao. (2022) Predicting in vitro lung deposition behavior of combined dry powder inhaler via rheological properties. European Journal of Pharmaceutics and Biopharmaceutics 181, pages 195-206.
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Raj Kumar, Piyush Mehta, Konathala Ravi Shankar, Manju A. K. Rajora, Yogendra Kumar Mishra, Ebrahim Mostafavi & Ajeet Kaushik. (2022) Nanotechnology-Assisted Metered-Dose Inhalers (MDIs) for High-Performance Pulmonary Drug Delivery Applications. Pharmaceutical Research 39:11, pages 2831-2855.
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N. S. Yubitskaya, M. V. Antonyuk & T. A. Gvozdenko. (2022) Possibilities of respiratory rehabilitation in correction of small airway dysfunction. Bulletin Physiology and Pathology of Respiration:85, pages 131-142.
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Dhananjay Yadav, Peninah M. Wairagu, Minseok Kwak & Jun-O Jin. (2022) Nanoparticle-Based Inhalation Therapy for Pulmonary Diseases. Current Drug Metabolism 23:11, pages 882-896.
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William B. Feldman, Doni Bloomfield, Reed F. Beall & Aaron S. Kesselheim. (2022) Brand-name market exclusivity for nebulizer therapy to treat asthma and COPD. Nature Biotechnology 40:9, pages 1319-1325.
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David M. G. Halpin & Donald A. Mahler. (2022) A Systematic Review of Published Algorithms for Selecting an Inhaled Delivery System in Chronic Obstructive Pulmonary Disease. Annals of the American Thoracic Society 19:7, pages 1213-1220.
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Rashmi S & Nanditha Krishna. (2022) IoT Enabled Therapeutical Assistance Unit for COPD Patient Drug Delivery and Management. IoT Enabled Therapeutical Assistance Unit for COPD Patient Drug Delivery and Management.
Zia Ul Mustafa, Muhammad Salman, Irsa Jamal, Mahpara Kanwal, Muhammad Bilal Riaz, Syed Shahzad Hasan & Amer Hayat Khan. (2022) A pharmacist-led educational intervention to improve nebulization-related knowledge and practices of nursing staff: a pre–post interventional study from Pakistan. Drugs & Therapy Perspectives 38:4, pages 194-200.
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Qomariyatus Sholihah, Dewi Hardiningtyas, Kumoro Lenggono, Stephan Adriansyah Hulukati, Wahyudi Kuncoro & Eko Tri Wisuda. (2022) Usability Prototype Smart Portable Nebulizer for Self-care with Respiratory Disorders at Home. Open Access Macedonian Journal of Medical Sciences 10:E, pages 171-176.
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Mohamed Talaat, Xiuhua Si & Jinxiang Xi. (2022) Effect of MDI Actuation Timing on Inhalation Dosimetry in a Human Respiratory Tract Model. Pharmaceuticals 15:1, pages 61.
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Timothy Nguyen & Maureen George. (2021) Antimuscarinic Medications for Chronic Obstructive Pulmonary Disease. The Journal for Nurse Practitioners 17:7, pages 894-895.
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Maria F. Acosta, Michael D. Abrahamson, David Encinas-Basurto, Jeffrey R. Fineman, Stephen M. Black & Heidi M. Mansour. (2020) Inhalable Nanoparticles/Microparticles of an AMPK and Nrf2 Activator for Targeted Pulmonary Drug Delivery as Dry Powder Inhalers. The AAPS Journal 23:1.
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Maria F. Acosta, Priya Muralidharan, Carissa L. Grijalva, Michael D. Abrahamson, Don HayesJr.Jr., Jeffrey R. Fineman, Stephen M. Black & Heidi M. Mansour. (2021) Advanced therapeutic inhalation aerosols of a Nrf2 activator and RhoA/Rho kinase (ROCK) inhibitor for targeted pulmonary drug delivery in pulmonary hypertension: design, characterization, aerosolization, in vitro 2D/3D human lung cell cultures, and in vivo efficacy . Therapeutic Advances in Respiratory Disease 15, pages 175346662199824.
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Maria F. Acosta, Priya Muralidhran, Michael D. Abrahamson, Carissa L. Grijalva, Megan Carver, Haiyang Tang, Christina Klinger, Jeffrey R. Fineman, Stephen M. Black & Heidi M. Mansour. (2020) Comparison of l-Carnitine and l-Carnitine HCL salt for targeted lung treatment of pulmonary hypertension (PH) as inhalation aerosols: Design, comprehensive characterization, in vitro 2D/3D cell cultures, and in vivo MCT-Rat model of PH. Pulmonary Pharmacology & Therapeutics 65, pages 101998.
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