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International Journal of Chronic Obstructive Pulmonary Disease Volume 16, 2021 - Issue
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Original Research

Nemiralisib in Patients with an Acute Exacerbation of COPD: Placebo-Controlled, Dose-Ranging Study

William A Fahy1 Discovery Medicine, GlaxoSmithKline R&D, GSK House, Brentford, UKCorrespondence[email protected]
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Farshid Homayoun-Valiani2 Global Clinical Operations, GlaxoSmithKline, GSK House, Brentford, UKView further author information
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Anthony Cahn3 Discovery Medicine, GlaxoSmithKline, Stevenage, UKView further author information
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Jon Robertson4 Biostatistics, GlaxoSmithKline R&D, Stevenage, UKView further author information
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Alison Templeton4 Biostatistics, GlaxoSmithKline R&D, Stevenage, UKView further author information
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Wilhelmine H Meeraus5 Respiratory Epidemiology, Value Evidence and Outcomes, GlaxoSmithKline R&D, GSK House, Brentford, UKORCID Iconhttps://orcid.org/0000-0001-7476-8061View further author information
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Robert Wilson3 Discovery Medicine, GlaxoSmithKline, Stevenage, UKView further author information
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Mike Lowings6 Regulatory Affairs, GlaxoSmithKline, GSK House, Brentford, UKView further author information
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Miriam Marotti7 Safety and Medical Governance, GlaxoSmithKline R&D, GSK House, Brentford, UKView further author information
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Sarah L West2 Global Clinical Operations, GlaxoSmithKline, GSK House, Brentford, UKView further author information
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Maggie Tabberer8 Value Evidence and Outcomes, GlaxoSmithKline R&D, GSK House, Brentford, UKView further author information
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Edith M Hessel9 Refractory Respiratory Inflammation Discovery Performance Unit, GlaxoSmithKline, Stevenage, UKORCID Iconhttps://orcid.org/0000-0002-2339-4482View further author information
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Pages 1637-1646 | Published online: 03 Jun 2021

Citations (9)

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Read on this site (2)

Mario Cazzola, Nicola A Hanania, Clive P Page & Maria Gabriella Matera. (2023) Novel Anti-Inflammatory Approaches to COPD. International Journal of Chronic Obstructive Pulmonary Disease 18, pages 1333-1352.
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Peng Guo, Rui Li, Tie Hua Piao, Chun Lan Wang, Xiao Lu Wu & Hong Yan Cai. (2022) Pathological Mechanism and Targeted Drugs of COPD. International Journal of Chronic Obstructive Pulmonary Disease 17, pages 1565-1575.
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Articles from other publishers (7)

Malcolm Begg, Augustin Amour, Emily Jarvis, Teresa Tang, Sara Santos Franco, Andrew Want, Misba Beerahee, Disala Fernando, Yakshitha Karkera, Clare Sander, Thomas Southworth, Dave Singh, Jonathan Clark, Sergey Nejentsev, Klaus Okkenhaug, Alison Condliffe, Anita Chandra, Anthony Cahn & Edward Banham Hall. (2023) An open label trial of nemiralisib, an inhaled PI3 kinase delta inhibitor for the treatment of Activated PI3 kinase Delta Syndrome. Pulmonary Pharmacology & Therapeutics 79, pages 102201.
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Nathaniel McClean, Jeffery D. Hasday & Paul Shapiro. 2023. Pulmonary Pharmacology. Pulmonary Pharmacology 145 178 .
Kun Pang, Wei Wang, Jia‐Xin Qin, Zhen‐Duo Shi, Lin Hao, Yu‐Yang Ma, Hao Xu, Zhuo‐Xun Wu, Deng Pan, Zhe‐Sheng Chen & Cong‐Hui Han. (2022) Role of protein phosphorylation in cell signaling, disease, and the intervention therapy. MedComm 3:4.
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Sarah Diver, Chris E. Brightling & Neil J. Greening. (2022) Novel Therapeutic Strategies in Asthma-Chronic Obstructive Pulmonary Disease Overlap. Immunology and Allergy Clinics of North America 42:3, pages 671-690.
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Isabel UWAGBOE, Ian M. ADCOCK, Federica LO BELLO, Gaetano CARAMORI & Sharon MUMBY. (2022) New drugs under development for COPD. Minerva Medica 113:3.
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Jean Piero Margaria, Lucia Moretta, Jose Carlos Alves-Filho & Emilio Hirsch. (2022) PI3K Signaling in Mechanisms and Treatments of Pulmonary Fibrosis Following Sepsis and Acute Lung Injury. Biomedicines 10:4, pages 756.
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E. Fagone, M. Fruciano, E. Gili, G. Sambataro & Carlo Vancheri. 2022. PI3K and AKT Isoforms in Immunity. PI3K and AKT Isoforms in Immunity 437 466 .

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